全文获取类型
收费全文 | 1158篇 |
免费 | 106篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 19篇 |
儿科学 | 89篇 |
妇产科学 | 60篇 |
基础医学 | 136篇 |
口腔科学 | 192篇 |
临床医学 | 109篇 |
内科学 | 194篇 |
皮肤病学 | 37篇 |
神经病学 | 50篇 |
特种医学 | 91篇 |
外科学 | 110篇 |
综合类 | 26篇 |
一般理论 | 1篇 |
预防医学 | 61篇 |
眼科学 | 9篇 |
药学 | 47篇 |
中国医学 | 1篇 |
肿瘤学 | 38篇 |
出版年
2023年 | 6篇 |
2022年 | 13篇 |
2021年 | 29篇 |
2020年 | 14篇 |
2019年 | 22篇 |
2018年 | 23篇 |
2017年 | 22篇 |
2016年 | 28篇 |
2015年 | 44篇 |
2014年 | 38篇 |
2013年 | 50篇 |
2012年 | 74篇 |
2011年 | 65篇 |
2010年 | 68篇 |
2009年 | 49篇 |
2008年 | 64篇 |
2007年 | 46篇 |
2006年 | 48篇 |
2005年 | 51篇 |
2004年 | 47篇 |
2003年 | 35篇 |
2002年 | 16篇 |
2001年 | 15篇 |
2000年 | 16篇 |
1999年 | 24篇 |
1998年 | 32篇 |
1997年 | 38篇 |
1996年 | 37篇 |
1995年 | 28篇 |
1994年 | 20篇 |
1993年 | 18篇 |
1992年 | 15篇 |
1991年 | 8篇 |
1990年 | 15篇 |
1989年 | 17篇 |
1988年 | 23篇 |
1987年 | 23篇 |
1986年 | 13篇 |
1985年 | 17篇 |
1984年 | 5篇 |
1983年 | 6篇 |
1982年 | 7篇 |
1981年 | 11篇 |
1980年 | 4篇 |
1979年 | 3篇 |
1977年 | 6篇 |
1976年 | 6篇 |
1969年 | 2篇 |
1954年 | 1篇 |
1927年 | 1篇 |
排序方式: 共有1270条查询结果,搜索用时 15 毫秒
61.
Leonice Fumiko Sato Kurebayashi Maria Júlia Paes da Silva 《Revista latino-americana de enfermagem》2014,22(3):371-378
Objective
this randomized single blind clinical study aimed to evaluate the efficacy of auriculotherapy with and without a protocol for reducing stress levels among nursing staff.Method
a total of 175 nursing professionals with medium and high scores according to Vasconcelos'' Stress Symptoms List were divided into 3 groups: Control (58), Group with protocol (58), Group with no protocol (59). They were assessed at the baseline, after 12 sessions, and at the follow-up (30 days).Results
in the analysis of variance, statistically significant differences between the Control and Intervention groups were found in the two evaluations (p<0.05) with greater size of effect indices (Cohen) for the No protocol group. The Yang Liver 1 and 2, Kidney, Brain Stem and Shen Men were the points most used.Conclusion
individualized auriculotherapy, with no protocol, could expand the scope of the technique for stress reduction compared with auriculotherapy with a protocol. NCT: 01420835 相似文献62.
Karina Morais Faria Thais Bianca Brandão Ana Carolina Prado Ribeiro Adriele Ferreira Gouvêa Vasconcellos Icaro Thiago de Carvalho Fernando Freire de Arruda Gilberto Castro Junior Vanessa Cristina Gross Oslei Paes Almeida Marcio Ajudarte Lopes Alan Roger Santos-Silva 《Journal of endodontics》2014
Introduction
Teeth are often included in the radiation field during head and neck radiotherapy, and recent clinical evidence suggests that dental pulp is negatively affected by the direct effects of radiation, leading to impaired sensitivity of the dental pulp. Therefore, this study aimed to investigate the direct effects of radiation on the microvasculature, innervation, and extracellular matrix of the dental pulp of patients who have undergone head and neck radiotherapy.Methods
Twenty-three samples of dental pulp from patients who finished head and neck radiotherapy were analyzed. Samples were histologically processed and stained with hematoxylin-eosin for morphologic evaluation of the microvasculature, innervation, and extracellular matrix. Subsequently, immunohistochemical analysis of proteins related to vascularization (CD34 and smooth muscle actin), innervation (S-100, NCAM/CD56, and neurofilament), and extracellular matrix (vimentin) of the dental pulp was performed.Results
The morphologic study identified preservation of the microvasculature, nerve bundles, and components of the extracellular matrix in all studied samples. The immunohistochemical analysis confirmed the morphologic findings and showed a normal pattern of expression for the studied proteins in all samples.Conclusions
Direct effects of radiotherapy are not able to generate morphologic changes in the microvasculature, innervation, and extracellular matrix components of the dental pulp in head and neck cancer patients. 相似文献63.
John Lennon Silva-Cunha Israel Leal Cavalcante Caio Csar da Silva Barros Fernanda Arago Felix Luan Borges Venturi Larissa Santos Amaral Rolim Csar Luis Porpino Santos da Silva-Júnior Emanuel Mendes Sousa ricka Janine Dantas da Silveira Michelle Agostini Mrio Jos Romanach Oslei Paes de Almeida Sílvia Ferreira de Sousa Bruno Augusto Benevenuto de Andrade 《Medicina oral, patología oral y cirugía bucal》2022,27(1):e35
64.
65.
Paul Tieu Bosco Paes Afrah Ahmed Davide Matino Anthony Chan Mihir Bhatt 《Pediatric blood & cancer》2020,67(4)
Neonatal inferior vena cava syndrome (IVCS), though uncommon, is associated with significant morbidity and mortality. Information on risk factors, diagnosis, treatment, and outcomes is limited. This review comprised 61 neonates across 33 reports. Thrombosis occurred in 98% and 42% involved a central venous catheter. Diagnosis was mainly established by ultrasound in 82%. Therapeutically, heparin was employed in 36% and thrombolysis in 18% of the cases. The overall mortality was 23%. An algorithm of clinical signs, investigation, and management is presented. Well‐designed prospective studies are needed to establish a concrete investigational approach to neonatal IVCS and institute safe, evidence‐based treatment. 相似文献
66.
Ana Maria Betim Paes Leme Vera Maria Cury Salemi Robert G. Weiss Jose Rodrigues Parga Bárbara Maria Ianni Charles Mady Roberto Kalil-Filho 《Journal of cardiac failure》2013,19(7):454-460
BackgroundThe influence of exercise on cardiac metabolic response in patients with Chagas disease is incompletely understood.Methods and ResultsChanges in cardiac energetic metabolism were investigated in Chagas disease patients before and during isometric handgrip exercise with 31P magnetic resonance spectroscopy (MRS). Twenty-eight patients (10 with systolic dysfunction: group I; 10 with normal systolic function and electrocardiogram (ECG) abnormalities: group II; and 8 asymptomatic without ECG abnormalities: group III) and 8 healthy control subjects (group C) were evaluated by electrocardiogram, echocardiogram, functional tests for coronary artery disease, and image-selected localized cardiac 31P-MRS. The myocardial phosphocreatine to [β-phosphate]adenosine triphosphate ratio (PCr/β-ATP) was measured at rest and during isometric handgrip exercise. Exercise testing or 99mTc–sestamibi scintigraphy were negative for myocardial ischemia in all individuals. At rest, cardiac PCr/β-ATP was decreased in all Chagas groups (1.23 ± 0.37) versus group C (1.88 ± 0.08; P < .001) and was lower in group I (0.89 ± 0.24) versus groups II (1.44 ± 0.23) and III (1.40 ± 0.37; P < .001). There was no stress-induced change in cardiac PCr/β-ATP (1.88 ± 0.08 at rest vs 1.89 ± 0.08 during exercise; P = NS) in group C. Mean cardiac PCr/β-ATP was 0.89 ± 0.24 and 0.56 ± 0.21 at rest and during exercise, respectively, in group I (37% decrease; P < .001). In group II, PCr/β-ATP was 1.44 ± 0.23 at rest and 0.97 ± 0.37 during exercise (33% decrease; P < .001). In group III, PCr/β-ATP was 1.40 ± 0.37 at rest and 0.60 ± 0.19 during exercise (57% decrease; P < .001).ConclusionsMyocardial high-energy phosphates are reduced at rest in Chagas heart disease patients, and the reduction is greater in patients with left ventricular dysfunction. Regardless of left ventricular function, Chagas patients exhibit an exercise-induced decline in cardiac high-energy phosphates consistent with myocardial ischemia, suggesting the possibility that this metabolic approach may offer a tool to probe new interventions in Chagas disease patients. 相似文献
67.
68.
69.
70.
A Ascari‐Raccagni A Dondas MG Righini G Trevisan 《Journal of the European Academy of Dermatology and Venereology》2010,24(8):926-929
Background The repair of an alar nasal defect is a frequent challenge for dermatologic surgeons for reasons of the high rate of non‐melanoma cancers in the area. Objective Our aim was to describe the use of an east–west cheek‐based flap (horizontal advancement flap) to repair a surgical defect on the nose ala. Methods Benefits and limits of this surgical procedure are evaluated. Result The resulting S‐shaped scar was well‐camouflaged among the natural skin lines (melolabial fold and melonasal junction). No architectural distortion of the nose resulted from the procedure. Conclusion In selected patients with small‐to‐medium‐size defects of the nasal ala, the horizontal advancement flap is a simple, reliable and aesthetic reconstruction option. 相似文献