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A radiographic study of the ligamentous anatomy of the ankle 总被引:1,自引:0,他引:1
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Isolauri E Ouwehand AC Laitinen K 《Acta paediatrica (Oslo, Norway : 1992). Supplement》2005,94(449):110-114
The increased prevalence of atopic diseases, i.e. atopic eczema, allergic rhinitis and asthma, has been described as the epidemic of the 21st century in Western societies. New approaches in the fight against allergic diseases are clearly called for, the target being the persistence of the allergic responder pattern beyond infancy. The advantage afforded by elimination diets lies in the silencing of specific allergic inflammation induced by an offending food. Novel nutritional approaches, beyond the treatment of food allergies, have recently attracted research interest subsequent to the identification of the immunomodulatory potential of specific dietary compounds. Dietary lipids as immunomodulators may prevent allergic sensitization by down-regulating inflammatory response whilst protecting the epithelial barrier. Probiotic bacteria have been shown to reinforce the different lines of gut defence: immune exclusion, immune elimination and immune regulation. On this basis, the strategy against allergic disease proposed here is based on the administration of tolerogenic gut-processed peptide fragments of a specific protein, in addition to the use of specific dietary compounds such as fatty acids and antioxidants, and introducing a microbial stimulus for the immature immune system by means of cultures of beneficial live micro-organisms characteristic of the healthy infant gut microbiota. 相似文献
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The Dutch Alcohol and Drug Information System (LADIS) has been operational since 1986 and covers 95% of all alcohol and drug treatment out-patient services in the Netherlands. From 1994 it has been operating as a population-based register in which contact episodes of individual clients can be linked over time with a unique code made anonymous by encryption methods. With the acceptance of the welfare law in 1998, the flow of various categories of data (diagnostic, demographic, treatment and evaluation) and the continuity of LADIS have been secured. Data capture, processing and quality control are highly automated. The information from LADIS concerns annual reports as well as numerous profiles of various groups of clients. The implementation of LADIS and the high degree of standardisation of the data collected have been strongly facilitated by the use of the underlying institutional application ADDICTIS. Within the LADIS framework, almost 95% of the (European) Treatment Demand Indicator Protocol data set on drugs can be collected. 相似文献
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Coralline hydroxyapatite bone graft substitutes: preliminary report of radiographic evaluation 总被引:1,自引:0,他引:1
A new bone graft substitute made by conversion of the calcium carbonate exoskeleton of reef-building sea coral into hydroxyapatite has recently become clinically available. The normal radiographic appearance of two forms of this material is described. In the immediate postoperative period, the exoskeletal architecture of these implants is readily appreciated. With graft incorporation over the ensuing months, their intrinsic structure is gradually lost in association with poor marginal definition. Evolving radiographic findings reflect the biocompatible nature of these implants, which provides the potential for ingrowth of native bone with preservation of the coralline scaffold, resulting in enhanced biomechanical properties. 相似文献
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A M Kootte A R Janssens D K Ouwehand A M van Leeuwen 《Nederlands tijdschrift voor geneeskunde》2001,145(48):2340-2343
In a 68-year-old woman with severe chronic hepatitis an extensive investigation revealed no other cause than the use of sotalol for 10 months due to atrial fibrillation. Once the use of the medication had been discontinued the patient's symptoms quickly disappeared and the liver function disorders normalised within 5 months. Sotalol is a beta-adrenergic receptor blocking and anti-arrhythmic agent. It is widely used in patients with supraventricular and ventricular arrhythmias. An adverse effect in terms of liver damage is not known. The pathogenesis of the observed hepatitis remained an enigma because sotalol is a hydrophilic substance which is not metabolized by the liver and is cleared by the kidneys unchanged. 相似文献