A novel genital human papillomavirus (HPV), HPV type 74, found in immunosuppressed patients.

The genome of a novel human papillomavirus (HPV) type, HPV74, was cloned from an iatrogenically immunosuppressed woman with persisting low-grade vaginal intraepithelial neoplasia. HPV74 was found to be phylogenetically related to the low-risk HPV types 6, 11, 44, and 55. HPV74 or a variant of this type was found in specimens from three additional immunosuppressed women but not in about 3,000 anogenital specimens from immunocompetent patients.     

Surgical therapy of acute cholecystitis--advantages of early operation]

229 patients with an acute cholecystitis were operated on at the Surgical University Hospital of Ulm between 3/1982 and 6/1990. 42.3% of the patients were older than 70 years, the mean age being 64.3 years. 51.5% suffered from a complicated form of the disease. Intercurrent diseases were preoperatively found in 76%. Intraoperative complications of a technical nature occurred in 3.1%. The overall postoperative morbidity rate was 54%, with 9.4% of local problems, and showed a clear dependency on age and the number of preexisting risk factors. 31% had to undergo reoperation. The overall mortality rate was 2.6%, with a 0% mortality for patients under 65 years. The number of preexisting risk factors clearly correlated the period of hospitalisation, which was 16.1 days on average. In symptomatic gallstone diseases an early elective cholecystectomy should be strongly considered, especially in aged and multimorbid patients.     

Comparisons of craniofacial features of English children with Angle Class II division 1 and Angle Class I occlusions

This study was based on a cephalometric analysis of 68 English children composed of two groups: one group exhibiting Angle Class II division 1 occlusion and the other with Angle Class I occlusion.

The object of this study was to investigate differences in the dimensions of the craniofacial complex between the Class II division 1 group and the Class I group.

It was found that the only significant differences between the Class II division 1 and Class I groups with regard to craniofacial dimensions were a shorter mandible, a higher maxillary-mandibular plane angle, and a marked proclination of the upper incisor teeth in the former group.