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81.
Deniz O Aygül R Kotan D Ozdemir G Odabaş FO Kaya MD Ulvi H 《Rheumatology international》2012,32(5):1285-1290
The aim of this study was to evaluate the efficacy of steroid injection for the treatment of the carpal tunnel syndrome (CTS),
with F-wave parameters and sympathetic skin response (SSR). Seventeen hands of 10 women patients were treated with local steroid
injection with 2-month follow-up. All patients underwent single injection into the carpal tunnel. Response to injection was
measured nerve conduction studies (NCSs), median nerve F waves, and SSR before and after treatment. To determine the normal
values, 42 hands of 21 healthy women were also studied. There was a significant improvement of sensory and motor nerve conduction
values when compared to baseline values (P < 0.01). At the end of follow-up period, the median sensory distal latency and the sensory latency differences between the
median and the ulnar nerve were improved 35 and 65%, respectively. The maximum, mean F-wave amplitudes and chronodispersion
showed a slight improvement with respect to baseline values and controls, but statistical significance was not achieved after
treatment. Although no statistically significant improvements were observed in SSR parameters, slightly decreased amplitudes
and increased habituation of SSR were noted at the end of the treatment. The present study shows that the local steroid injection
results in improvement in NCSs values, but the F-wave parameters were not effectual in short-term outcome of CTS treatment.
These findings suggest that the sensory latency differences between the median and the ulnar wrist-to-digit 4 are better parameters
in the median nerve recovery after treatment than the median sensory distal latency. Furthermore, the SSR does not seem to
be a sensitive method in follow-up of CTS treatment. 相似文献
82.
Background
Cancer cachexia is a devastating condition leading to loss of function and independence, decreased performance status, decreased quality of life, and poor prognosis. Adipokines play a role in a wide variety of physiological or pathological processes, including immunity and inflammation, in addition to having significant effects on metabolism and lipogenesis. The objective of the present study was to investigate the relationship of adipokines and systemic inflammation in weight-losing advanced-stage non-small-cell lung cancer (NSCLC) patients. 相似文献83.
Oguz Ozan PhD Kaan Orhan PhD Secil Aksoy DDS Murat Icen DDS Burak Bilecenoglu PhD Bayram Ufuk Sakul PhD 《Journal of prosthodontics》2013,22(1):42-48
Purpose: The aim of this study was to compare vertical and horizontal mandibular alveolar bone resorption by measuring bone morphological variation in Kennedy Class II removable partial denture (RPD) wearers and non‐wearers using cone‐beam computed tomography (CBCT). Materials and Methods: In total, 124 sites in the CBCT scans of 62 (29 RPD non‐wearers, 33 RPD wearers) Kennedy Class II patients were analyzed retrospectively. Three‐dimensional representations of the mandible with superimposed cross‐sectional slices were developed with the CBCT scans to evaluate the mandibular alveolar height and width by measuring distances between the mandibular canal, mylohyoid ridge, alveolar crest, and lower border of the mandible in four regions (eight sites) of Kennedy Class II non‐wearers and wearers of RPDs. Results: Mandibular alveolar bone height and width were significantly lower in edentulous sites when compared with dentate sites in both Kennedy Class II non‐wearers and wearers of RPDs (p < 0.05). Additionally, mean vertical and horizontal mandibular bone resorption was significantly higher in RPD wearers than in non‐wearers (p < 0.05). Conclusions: Vertical and horizontal alveolar bone resorption was found to be higher in the RPD wearing patients when comparing the dentate and edentulous sites. 相似文献
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Selim Kayaci Yusuf Sukru Caglar Orhan Bas Mehmet Faik Ozveren 《Clinical neurology and neurosurgery》2013
Objective
The purpose of this study is to examine the perforating arteries (PAs) in the proximal part of the posterior inferior cerebellar artery (PICA) for surgical approaches to the brain stem and fourth ventricle, and to stress their importance in microsurgical procedures.Methods
Twenty-six adult cadaver obtained from routine autopsies were used. During the examination, the PAs and the segmental structure of the proximal part of the PICAs and their relation to the neighbouring anatomical structures were demonstrated.Results
We classified the PICAs into 4 types on the basis of the distance of the middle point of the width of the caudal loop to the midline, and their presence or absence as Group A (symmetrical, anterior medullary type: 26.9%), Group B (lateral medullary type: 15.4%), Group C (asymmetrical type: 38.5%), and Group D (unilateral type: 19.2%). The number of the PAs in the tonsillomedullary segment and the caudal loop was higher than those originating from the other segments.Conclusions
Approaches to the medial or lateral of the PICA should be made in a way that protects the PAs (avoiding retraction of the PICA). Otherwise the PAs will be damaged and as a result brain stem ischaemia may occur, which can have serious clinical outcomes. 相似文献87.
İlker Ertuğrul Sinem Akgül Orhan Derman Tevfik Karagöz Nuray Kanbur 《Eating disorders》2013,21(3):289-296
ABSTRACTStudies have shown that a prolonged P-wave dispersion is a risk factor for the development of atrial fibrillation. The aim of this study was to evaluate P-wave dispersion in adolescents with anorexia nervosa at diagnosis. We evaluated electrocardiographic findings, particularly the P-wave dispersion, at initial assessment in 47 adolescents with anorexia nervosa. Comparison of P-wave dispersion between adolescents with anorexia nervosa and controls showed a statistically significant higher P-wave dispersion in patients with anorexia nervosa (72 ± 16.3 msec) when compared to the control group (43.8 ± 9.5 msec). Percent of body weight lost, lower body mass index, and higher weight loss rate in the patients with anorexia nervosa had no effect on P-wave dispersion. Due to the fact that anorexia nervosa has a high mortality rate we believe that cardiac pathologies such as atrial fibrillation must also be considered in the medical evaluation. 相似文献
88.
A platinum blue complex exerts its cytotoxic activity via DNA damage and induces apoptosis in cancer cells 下载免费PDF全文
Zelal Adiguzel Seniz Ozalp‐Yaman Gokalp Celik Safia Salem Tugba Bagci‐Onder Filiz Senbabaoglu Yüksel Cetin Ceyda Acilan 《Chemical biology & drug design》2017,90(2):210-224
Here, we describe the characteristics of a Pt‐blue complex [Pt4(2‐atp)8(H2O)(OH)] (2‐atp: 2‐aminothiophenol) as a prodrug for its DNA‐binding properties and its use in cancer therapy. The nature of the interaction between the Pt‐blue complex and DNA was evaluated based on spectroscopic measurements, the electronic absorption spectra, thermal behavior, viscosity, fluorometric titration, and agarose gel electrophoresis. Our results suggested that the compound was able to partially intercalate DNA and appeared to induce both single‐ and double‐stranded breaks (DBS) on DNA in vitro, but no DSBs in cells. The ability of the compound to induce DNA damage was dependent on reactive oxygen species (ROS) in vitro. There was also elevated formation of ROS and SOD expression in response to drug treatment in cell culture. The complex was found to be more cytotoxic to cancer cells in comparison with noncancer controls using WST‐1 assay. The mean of cell death was determined to be apoptosis as assessed via biochemical, morphological, and molecular observations, including DNA condensation/fragmentation analysis, live cell imaging microscopy, TUNEL analyses, and increase in the levels of pro‐apoptotic genes such as Bag3, Bak, Bik, Bmf, and Hrk. Hence, the Pt‐blue complex under study grants premise for further studies. 相似文献
89.
Sezer Eda Can Demirden Birsen Demirkaya eref Bulut Giray Akkulak Merve Evin Emre Adal Orhan 《Neurological sciences》2022,43(4):2611-2620
Neurological Sciences - Patients with multiple sclerosis (MS) have significantly lower vitamin D levels. Cholesterol is known to be the precursor for vitamin D synthesis, and cholesterol removal is... 相似文献
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