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111.
High concordance between clinical diagnosis of epidermolysis bullosa and immunofluorescence with a small,well‐matched antibody panel
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![点击此处可从《The Australasian journal of dermatology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
112.
Michal Stein Shelly Lipman-Arens Kfir Oved Asi Cohen Ellen Bamberger Roy Navon Olga Boico Tom Friedman Liat Etshtein Meital Paz Tanya M. Gottlieb Or Kriger Yura Fonar Ester Pri-Or Renata Yacobov Yaniv Dotan Amit Hochberg Moti Grupper Adi Klein 《Diagnostic microbiology and infectious disease》2018,90(3):206-213
Bacterial and viral lower respiratory tract infections (LRTIs) are often clinically indistinguishable, leading to antibiotic overuse. We compared the diagnostic accuracy of a new assay that combines 3 host-biomarkers (TRAIL, IP-10, CRP) with parameters in routine use to distinguish bacterial from viral LRTIs. Study cohort included 184 potentially eligible pediatric and adult patients. Reference standard diagnosis was based on adjudication by an expert panel following comprehensive clinical and laboratory investigation (including respiratory PCRs). Experts were blinded to assay results and assay performers were blinded to reference standard outcomes. Evaluated cohort included 88 bacterial and 36 viral patients (23 did not fulfill inclusion criteria; 37 had indeterminate reference standard outcome). Assay distinguished bacterial from viral LRTI patients with sensitivity of 0.93 ± 0.06 and specificity of 0.91 ± 0.09, outperforming routine parameters, including WBC, CRP and chest x-ray signs. These findings support the assay's potential to help clinicians avoid missing bacterial LRTIs or overusing antibiotics. 相似文献
113.
José Tiago Sequeira Lopes da Silva Olga González Casas Verónica Bejarano Moguel Maria Lobo Pascua Antonio López-Santamaría Redondo Remigio Cordero Torres 《Gastroenterologia y hepatologia》2013
Somatostatin and somatostatin analogues are considered very useful for the treatment of hormone producing tumors and acute variceal bleeding. They have also been proposed for the treatment of acute pancreatitis and for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis although clinical trials have failed to show any efficacy. The authors report the case of a 45-year-old man, recently diagnosed of acromegaly, which developed an acute pancreatitis shortly after his first injection of lanreotide autogel. The patient developed a severe dilatation of his hypocontractile gallbladder with distension of the intra and extrahepatic biliary ducts, the choledochus and the main pancreatic duct, without lithiasis or other abnormalities at the papilla, which resolved spontaneously in a month. We consider that lanreotide most likely induced a functional spasm of the Sphincter of Oddi, with impairment of the biliary-pancreatic outflow, leading to an acute pancreatitis, and review the literature concerning this drug related pancreatitis. 相似文献
114.
Imaging the right heart pulmonary circulation unit: Insights from advanced ultrasound techniques
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![点击此处可从《Echocardiography (Mount Kisco, N.Y.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Francesco Ferrara MD PhD Luna Gargani MD PhD Ellen Ostenfeld MD Michele D'Alto MD PhD Jaroslaw Kasprzak MD Damien Voilliot MD Christine Selton‐Suty MD Olga Vriz MD Alberto M. Marra MD Paola Argiento MD Anna A. Stanziola MD PhD Antonio Cittadini MD PhD Antonello D'Andrea MD PhD Eduardo Bossone MD PhD 《Echocardiography (Mount Kisco, N.Y.)》2017,34(8):1216-1231
The right heart pulmonary circulation unit (RH‐PCU) is a key determinant of prognosis in several cardiorespiratory diseases. Although right heart catheterization is considered the gold standard for pulmonary hemodynamic assessment, a comprehensive cardiovascular ultrasound approach is an essential step in the diagnostic–prognostic clinical pathway of patients with suspect or overt pulmonary hypertension. The exponential development of advanced ultrasound techniques (strain, 3‐dimensional echocardiography and lung ultrasound) has led to new insights into the evaluation of RH‐PCU structure and function, overcoming some limitations of standard Doppler echocardiography. In the near future, exercise Doppler echocardiography may become a useful technique for detecting a latent stage of pulmonary hypertension and for evaluating right ventricular contractile reserve. 相似文献
115.
116.
Treatment and primary prevention in people who inject drugs for chronic hepatitis C infection: is elimination possible in a high‐prevalence setting?
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![点击此处可从《Addiction (Abingdon, England)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
117.
Implementing Dementia Care Mapping to develop person‐centred care: results of a process evaluation within the Leben‐QD II trial
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![点击此处可从《Journal of clinical nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
118.
Once facing the most severe HIV epidemic in Eastern Europe, Ukraine has built an elaborate Monitoring and Evaluation (M&E) system to track the response to AIDS. This system was developed using recommendations and input from multiple international expert organizations and donors and, at the current stage, serves as a best practice model in many areas. The present paper aims to provide a comprehensive overview of the evolution of the M&E system in Ukraine since its inception. Notable achievements and challenges are described and illustrated by epidemiological data and the recommendations for future development are discussed. Unique experiences and advances in M&E in Ukraine may be useful to other countries facing similar epidemiological, structural or methodological issues. 相似文献
119.
Mary M. Sweeney Olga Rass Cara DiClemente Rebecca L. Schacht Hoa T. Vo Marc J. Fishman 《Journal of child & adolescent substance abuse》2018,27(4):211-226
Adolescent cannabis use is associated with working memory impairment. The present randomized controlled trial assigned adolescents ages 14 to 21 enrolled in cannabis use treatment to receive either working memory training (experimental group) or a control training (control group) as an adjunctive treatment. Cognitive function, drug use, and other outcomes were assessed before and after training. We observed few differences in cognitive, functional, or self-reported drug use outcomes as a function of training group, although tetrahydrocannabinol (THC) urinalysis results favored the experimental group. These findings are similar to previous studies in substance users, which have shown limited transfer effects for working memory training. 相似文献
120.
Risk of Active Tuberculosis among Index Case of Householders—A Long‐Term Assessment after the Conventional Contacts Study
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![点击此处可从《Public health nursing (Boston, Mass.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)