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11.
Techniques for measuring sulcal/gyral patterns in the brain as visualized through magnetic resonance scanning: BRAINPLOT and BRAINMAP. 总被引:1,自引:0,他引:1 下载免费PDF全文
N C Andreasen G Harris T Cizadlo S Arndt D S O''Leary V Swayze M Flaum 《Proceedings of the National Academy of Sciences of the United States of America》1994,91(1):93-97
A method for measuring sulcal and gyral patterns, using data derived from magnetic resonance (MR) scanning, is described. This method can be applied through two newly developed computer programs, BRAINPLOT and BRAINMAP. These programs provide quantitative measures of brain surface pattern. The method has been validated with postmortem brains, phantoms, and human MR data. The method is robust to detecting differences in brain surface anatomy between atrophic and nonatrophic brains. It appears to offer an efficient, fully automated, and accurate method for analyzing the large amounts of information generated through in vivo neuroimaging techniques. 相似文献
12.
13.
我科近3年来对21例眼球摘除患者均Ⅰ期行自体游离真皮脂肪瓣眼窝填充以矫正眼窝塌陷,追踪观察1~2年,未发现填充物脱出、移位及缝线崩开,义眼活动度良好,眼睑外观饱满,现报道如下。
1 临床资料
本组21例,男13例,女8例。年龄最大52岁,最小16岁。眼球破裂伤9例,慢性眼内炎(视力丧失)7例,先天性眼球萎缩2例,角膜葡萄肿3例。本组病例均为Ⅰ期眼球摘除联合眶内游离真皮脂肪瓣填入术,效果满意。 相似文献
14.
W. ZONDAG I. C. M. MOS D. CREEMERS‐SCHILD A. D. M. HOOGERBRUGGE O. M. DEKKERS J. DOLSMA M. EIJSVOGEL L. M. FABER H. M. A. HOFSTEE M. M. C. HOVENS G. J. P. M. JONKERS K. W. van KRALINGEN M. J. H. A. KRUIP T. VLASVELD M. J. M. DE VREEDE M. V. HUISMAN ON BEHALF OF THE HESTIA STUDY INVESTIGATORS 《Journal of thrombosis and haemostasis》2011,9(8):1500-1507
Summary. Background: Traditionally, patients with pulmonary embolism (PE) are initially treated in the hospital with low molecular weight heparin (LMWH). The results of a few small non‐randomized studies suggest that, in selected patients with proven PE, outpatient treatment is potentially feasible and safe. Objective: To evaluate the efficacy and safety of outpatient treatment according to predefined criteria in patients with acute PE. Patients and Methods: A prospective cohort study of patients with objectively proven acute PE was conducted in 12 hospitals in The Netherlands between 2008 and 2010. Patients with acute PE were triaged with the predefined criteria for eligibility for outpatient treatment, with LMWH (nadroparin) followed by vitamin K antagonists. All patients eligible for outpatient treatment were sent home either immediately or within 24 h after PE was objectively diagnosed. Outpatient treatment was evaluated with respect to recurrent venous thromboembolism (VTE), including PE or deep vein thrombosis (DVT), major hemorrhage and total mortality during 3 months of follow‐up. Results: Of 297 included patients, who all completed the follow‐up, six (2.0%; 95% confidence interval [CI] 0.8–4.3) had recurrent VTE (five PE [1.7%] and one DVT [0.3%]). Three patients (1.0%, 95% CI 0.2–2.9) died during the 3 months of follow‐up, none of fatal PE. Two patients had a major bleeding event, one of which was fatal intracranial bleeding (0.7%, 95% CI 0.08–2.4). Conclusion: Patients with PE selected for outpatient treatment with predefined criteria can be treated with anticoagulants on an outpatient basis. (Dutch Trial Register No 1319; http://www.trialregister.nl/trialreg/index.asp ). 相似文献
15.
Scattering of diffuse photon density waves by spherical inhomogeneities within turbid media: analytic solution and applications. 总被引:2,自引:0,他引:2 下载免费PDF全文
D A Boas M A O''Leary B Chance A G Yodh 《Proceedings of the National Academy of Sciences of the United States of America》1994,91(11):4887-4891
We present an analytic solution for the scattering of diffuse photon density waves by spherical inhomogeneities within turbid media. The analytic result is compared to experimental measurements. Close agreement between theory and experiment permits the use of the theory to determine the properties of unknown sphere-like objects embedded in turbid media. The analytic solution is extended to encompass several problems of practical interest in imaging, including the influence of multiple sources, multiple objects, and boundaries on the characterization of spherical inhomogeneities. We also extend the solution to encompass time-domain measurements. 相似文献
16.
Impact of the Right Ventricular Lead Position on Clinical End Points in CRT Recipients—A Subanalysis of the Multicenter Randomized SPICE Trial 下载免费PDF全文
STEFAN ASBACH M.D. CARSTEN LENNERZ M.D. VERENA SEMMLER M.D. CHRISTIAN GREBMER M.D. ULRICH SOLZBACH M.D. AXEL KLOPPE M.D. NORBERT KLEIN M.D. ISTVAN SZENDEY M.D. GEORGE ANDRIKOPOULOS M.D. STYLIANOS TZEIS M.D. CHRISTOPH BODE M.D. CHRISTOF KOLB M.D. †; ON BEHALF OF THE SPICE STUDY INVESTIGATORS 《Pacing and clinical electrophysiology : PACE》2016,39(3):261-267
17.
J. HARENBERG A. KAKKAR† D. BERGQVIST‡ T. BARROWCLIFFE§ B. CASU¶ J. FAREED P. MISMETTI†† F. A. OFOSU‡‡ W. RAAKE§§ M. SAMAMA¶¶ S. SCHULMAN ON BEHALF OF THE SUBCOMMITTEE ON CONTROL OF ANTICOAGULATION OF THE SSC OF THE ISTH 《Journal of thrombosis and haemostasis》2009,7(7):1222-1225
Summary. Based on the results of large clinical trials, several low-molecular-weight heparins (LMWHs) have been approved for prophylaxis and the treatment of venous and arterial thromboembolism. As a result of expiration or pending expiration of patent protection of the originator LMWHs, many generic or biosimilar LMWHs have been approved in some countries and more are likely to be approved elsewhere. Their greater availability may reduce the treatment costs. The Working Party on Requirements for Development of Biosimilar LMWHs of the Subcommittee on Control of Anticoagulation, Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis has reached a consensus on recommendations to ensure the quality of biosimilar LMWHs as compared with the originator LMWHs. 相似文献
18.
我院在1985年1月-1994年12月共收治慢性肾功能衰竭(CRF)患者185例,其中老年患者(≥60岁)53例(占28.6%),与同期住院的非老年患者(<60岁)132例(占71.4%)进行对比分析,发现老年人CRF在其基础疾病,临床表现,实验室检查,并发症及伴发病方面均有许多特点,并对老年人CRF的治疗及与预后有关的因素略加讨论。 相似文献
19.
PREMEDICATION IS A NECESSARY PART OF PEDIATRIC ANESTHESIA: ABRAHAM ROSENBAUM MD ZEEV N. KAIN MD †‡ PREMEDICATION IN PEDIATRIC ANESTHESIA SHOULD BE INDIVIDUALIZED THE CHOICE OF PHARMACOLOGIC AGENT SHOULD BE RECONSIDERED: PETER LARSSON MD PER-ARNE LÖNNQVIST MD DEAA FRCA PHD † MODERATOR: ANDREW R. WOLF MD FRCA 《Paediatric anaesthesia》2009,19(9):817-828
Behind the multiple arguments for and against the use of premedication, sedative drugs in children is a noble principle that of minimizing psychological trauma related to anesthesia and surgery. However, several confounding factors make it very difficult to reach didactic evidence-based conclusions. One of the key confounding issues is that the nature of expectations and responses for both parent and child vary greatly in different environments around the world. Studies applicable to one culture and to one hospital system (albeit multicultural) may not apply elsewhere. Moreover, the study of hospital-related distress begins at the start of the patient's journey and ends long after hospital discharge; it cannot be focused completely on just the moment of anesthetic induction. Taking an example from actual practice experience, the trauma caused by the actual giving of a premedication to a child who absolutely does not want it and may struggle may not be recorded in a study but could form a significant component of overall effect and later psychological pathology. Clearly, attitudes by health professionals and parents to the practice of routine pediatric premedication, vary considerably, often provoking strong opinions. In this pro–con article we highlight two very different approaches to premedication. It is hoped that this helps the reader to critically re-evaluate a practice, which was universal historically and now in many centers is more selective. 相似文献
20.
The management of moderate to severe atopic dermatitis in adults with topical fluticasone propionate
Van Der Meer Glazenburg Mulder Eggink & Coenraads ON BEHALF OF THE NETHERLANDS ADULT ATOPIC DERMATITIS STUDY GROUP 《The British journal of dermatology》1999,140(6):1115-1121
This study was designed to investigate a long-term therapeutic strategy for the management of recurring atopic dermatitis (AD) in adults using fluticasone propionate (FP) ointment (CutivateTM ) whereby FP could help to prevent a relapse of AD once symptoms were under control. Adult patients with chronic, moderate to severe AD entered this multicentre study. All patients were initially treated with FP 0.005% (g/g) ointment in two different regimens. Patients whose AD had been completely healed by these treatments then entered a long-term treatment phase applying FP or placebo ointment once daily, two times per week for 16 weeks to 'known' healed lesions. By the end of the initial treatment period, mean SCORAD values had significantly ( P < 0.0005) improved from baseline. Patients who entered the maintenance phase and were treated with intermittent FP for up to 16 weeks, demonstrated its superior efficacy ( P = 0.018) over placebo, maintaining the improvements achieved after the initial treatment phase, reducing risk of relapse and delaying time to relapse ( P = 0.013). No significant changes were detected in either treatment group in serum cortisol levels or in skin thickness measurements. Intermittent FP applied two times per week maintained a significant level of control, and delayed relapse of AD by comparison with placebo. 相似文献