全文获取类型
收费全文 | 32063篇 |
免费 | 2095篇 |
国内免费 | 126篇 |
专业分类
耳鼻咽喉 | 333篇 |
儿科学 | 441篇 |
妇产科学 | 316篇 |
基础医学 | 3088篇 |
口腔科学 | 7214篇 |
临床医学 | 1701篇 |
内科学 | 6143篇 |
皮肤病学 | 485篇 |
神经病学 | 2104篇 |
特种医学 | 1221篇 |
外科学 | 4906篇 |
综合类 | 121篇 |
一般理论 | 1篇 |
预防医学 | 967篇 |
眼科学 | 602篇 |
药学 | 1860篇 |
中国医学 | 34篇 |
肿瘤学 | 2747篇 |
出版年
2023年 | 441篇 |
2022年 | 249篇 |
2021年 | 415篇 |
2020年 | 342篇 |
2019年 | 342篇 |
2018年 | 615篇 |
2017年 | 644篇 |
2016年 | 744篇 |
2015年 | 823篇 |
2014年 | 914篇 |
2013年 | 1117篇 |
2012年 | 1313篇 |
2011年 | 1442篇 |
2010年 | 1047篇 |
2009年 | 1156篇 |
2008年 | 1351篇 |
2007年 | 1453篇 |
2006年 | 1493篇 |
2005年 | 1402篇 |
2004年 | 1416篇 |
2003年 | 1349篇 |
2002年 | 1308篇 |
2001年 | 1128篇 |
2000年 | 1118篇 |
1999年 | 990篇 |
1998年 | 602篇 |
1997年 | 490篇 |
1996年 | 472篇 |
1995年 | 373篇 |
1994年 | 370篇 |
1993年 | 322篇 |
1992年 | 709篇 |
1991年 | 615篇 |
1990年 | 606篇 |
1989年 | 558篇 |
1988年 | 516篇 |
1987年 | 504篇 |
1986年 | 468篇 |
1985年 | 476篇 |
1984年 | 323篇 |
1983年 | 266篇 |
1982年 | 156篇 |
1981年 | 131篇 |
1979年 | 203篇 |
1978年 | 138篇 |
1977年 | 136篇 |
1975年 | 110篇 |
1973年 | 106篇 |
1972年 | 104篇 |
1970年 | 112篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
31.
Katsumi Shigemura Soichi Arakawa Kunito Yamanaka Nobuo Kataoka Keiji Yuien Masato Fujisawa 《International journal of urology》2007,14(10):935-938
OBJECTIVES: Lateral biopsies are thought to have a better cancer detection rate compared with standard sextant biopsies. This study aimed to determine whether lateral peripheral zone biopsies in Japanese men who underwent transrectal ultrasound-guided prostate biopsies provided a significantly higher cancer detection rate than sextant biopsies. METHODS: Between 1999 and 2004, data were collected from 461 men who underwent prostate biopsy and had enough data regarding the performance of lateral biopsies for statistical analysis. There were two categories in this study: (i) patients who underwent sextant prostate biopsies; and (ii) patients who underwent sextant biopsies plus lateral biopsies. RESULTS: Prostate cancer was detected in 141 (30.6%) of 461 patients. It was detected in 24 (22.2%) of 108 patients who underwent sextant biopsies and 117 (33.1%) of 353 patients who underwent sextant plus lateral biopsies. Lateral biopsies were not associated with a statistically higher rate of positive biopsy findings; however, we found a significantly higher ratio of patients with positive findings in those with prostate specific antigen (PSA) levels 10 ng/mL (one of 71, 1.4%) among those who had positive cores only in lateral biopsy samples (P < 0.0001). CONCLUSIONS: Lateral biopsies did not show a significantly higher detection ratio of prostate cancer compared to sextant biopsies. However, lateral biopsies were more effective than sextant biopsies in patients with lower PSA levels. Our findings might be useful for the establishment of biopsy strategies to detect prostate cancer, especially in patients with lower PSA levels. 相似文献
32.
33.
Neslihan Eminkahyagil DDS MSc PhD ; Selim Erkut DDS PhD 《Journal of prosthodontics》2006,15(5):316-320
Immediate chairside replacement of an extracted anterior tooth may contribute to a patient's comfort, treatment acceptance, and expectations of treatment; however, fabrication of a custom restoration in the anterior region of the mouth may result in an esthetic compromise for patients during the fabrication period. Chairside tooth replacement is an excellent application of fiber-reinforced composite resin technology. This article presents an innovative, affordable chairside procedure in which Ribbond Multi-Purpose Bondable Reinforcement Ribbon is used to replace a single extracted anterior tooth using the patient's own tooth. 相似文献
34.
Jessica Swoboda DDS H. Asuman Kiyak MA PhD Rigmor E. Persson DDS MSD G. Rutger Persson DDS PhD David K. Yamaguchi PhD Michael I. MacEntee LDS FRCD© PhD Christopher C.L. Wyatt BSc DMD MSc 《Special care in dentistry》2006,26(4):137-144
There is limited information regarding oral health status and other predictors of oral health‐related quality of life. An association between oral health status and perceived oral health‐related quality of life (OHQOL) might help clinicians motivate patients to prevent oral diseases and improve the outcome of some dental public health programs. This study evaluated the relationship between older persons' OHQOL and their functional dentition, caries, periodontal status, chronic diseases, and some demographic characteristics. A group of 733 low‐income elders (mean age 72.7 ISD=4.71, 55.6% women, 55.1% members of ethnic minority groups in the U.S. and Canada) enrolled in the TEETH clinical trial were interviewed and examined as part of their fifth annual visit for the trial. OHQOL was measured by the Geriatric Oral Health Assessment Index (GOHAI); oral health and occlusal status by clinical exams and the Eichner Index; and demographics via interviews. Elders who completed the four‐year assessment had an average of 21.5 teeth (SD=6.9). with 8.5 occluding pairs (SD=4.6), and 32% with occlusal contacts in all four occluding zones. Stepwise multiple regressions were conducted to predict total GOHAI and its subscores (Physical, Social, and Worry). Functional dentition was a less significant predictor than ethnicity and being foreign‐bom. These variables, together with gender, years since immigrating, number of carious roots, and periodontal status, could predict 32% of the variance in total GOHAI, 24% in Physical, 27% in Social, and 21 % in the Worry subscales. These findings suggest that functional dentition and caries influence older adults' OHQOL, but that ethnicity and immigrant status play a larger role. 相似文献
35.
36.
37.
David W. Farley DDS John D. Jones DDS Robert J. Cronin DDS MS 《Journal of prosthodontics》1998,7(2):84-90
Phonetics, esthetics, function, and comfort form the foundation of a successful dental prosthesis. A review of the mechanics of speech as well as common speech problems encountered with a removable maxillary prosthesis are presented. The use of a palatogram to aid the clinician in the assessment and resolution of speech problems associated with a maxillary denture is demonstrated. 相似文献
38.
M Yamashita K Inoue A Yamashita Y Fujita 《Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology》1990,81(4):554-560
Intravesical instillation of anti-cancer drugs for superficial urinary bladder cancer is generally carried out with the aim of prophylaxis against recurrence and chemotherapy against tumor. But since sensitivity of tumor cells to each anti-cancer drug differs individually, the anti-cancer drug to be used should also be decided individually. We selected a new sensitivity test, ATP-sensitivity-assay, which measures intracellular adenosine triphosphate (ATP) volume by Luciferin-Luciferase reaction, for the decision of the anti-cancer drug. In this paper, we evaluated the direct anti-tumor activity of the drugs that were decided by ATP-sensitivity-assay of intravesical chemotherapy. Six drugs, that are Doxorubicin (ADM), Mitomycin C (MMC), Pirarubicin (THP-ADM), Cytarabine (Ara-C), Bleomycin (BLM) and Cisplatin (CDDP) were tested in this research and size of tumors of six patients reduced to 34-93% after 6 times' installation. A woman got cystitis induced by ADM after 3 times' instillation but instillation was completed. ATP-sensitivity-assay is useful for deciding the anti-cancer drugs for intravesical chemotherapy and prophylaxis for superficial bladder cancer. 相似文献
39.
Histamine-type 2 antagonists (H2-blockers) as represented by cimentidine have been shown to adversely affect renal allograft function, particularly when coadministered
with cyclosporine, currently a major immunosuppressant. To determine whether or not a newer and more powerful H2-blocker, famotidine, would produce similar adverse effects, we assessed seven cyclosporine-treated renal allograft recipients
with regard to changes in their renal function on or off the H2-blocker over a one-week period. Neither the administration nor withdrawal of famotidine (20–40 mg/day) resulted in any significant
changes in serum creatine, BUN, urine output or cyclosporine trough levels, suggesting that famotidine can be safely administered
as an H2-blocker to cyclosporine-treated renal allograft recipients. 相似文献
40.
K Nakayama Y Nemoto Y Inoue T Mochizuki S B Soares Jr K Ohata J Katsuyama Y Onoyama K Wakasa 《AJNR. American journal of neuroradiology》1997,18(2):331
Cranial malignant fibrous histiocytomas are rare tumors. Most are hypervascular, destructive masses that are similar to other malignant lesions and to malignant fibrous histiocytomas found elsewhere in the body. We describe a myxoid malignant fibrous histiocytoma of the temporal bone, possibly of dural origin, with features that more closely resembled a meningioma at CT, MR imaging, and angiography. 相似文献