全文获取类型
收费全文 | 15629篇 |
免费 | 946篇 |
国内免费 | 88篇 |
专业分类
耳鼻咽喉 | 100篇 |
儿科学 | 363篇 |
妇产科学 | 368篇 |
基础医学 | 1922篇 |
口腔科学 | 314篇 |
临床医学 | 1520篇 |
内科学 | 3606篇 |
皮肤病学 | 219篇 |
神经病学 | 1736篇 |
特种医学 | 692篇 |
外科学 | 2301篇 |
综合类 | 66篇 |
一般理论 | 6篇 |
预防医学 | 1092篇 |
眼科学 | 312篇 |
药学 | 896篇 |
中国医学 | 33篇 |
肿瘤学 | 1117篇 |
出版年
2024年 | 22篇 |
2023年 | 192篇 |
2022年 | 285篇 |
2021年 | 502篇 |
2020年 | 383篇 |
2019年 | 449篇 |
2018年 | 529篇 |
2017年 | 411篇 |
2016年 | 496篇 |
2015年 | 492篇 |
2014年 | 670篇 |
2013年 | 848篇 |
2012年 | 1400篇 |
2011年 | 1374篇 |
2010年 | 715篇 |
2009年 | 601篇 |
2008年 | 1068篇 |
2007年 | 1031篇 |
2006年 | 896篇 |
2005年 | 921篇 |
2004年 | 795篇 |
2003年 | 680篇 |
2002年 | 622篇 |
2001年 | 97篇 |
2000年 | 77篇 |
1999年 | 106篇 |
1998年 | 135篇 |
1997年 | 76篇 |
1996年 | 89篇 |
1995年 | 63篇 |
1994年 | 50篇 |
1993年 | 56篇 |
1992年 | 55篇 |
1991年 | 43篇 |
1990年 | 33篇 |
1989年 | 38篇 |
1988年 | 36篇 |
1987年 | 23篇 |
1986年 | 22篇 |
1985年 | 32篇 |
1984年 | 20篇 |
1983年 | 29篇 |
1982年 | 14篇 |
1981年 | 20篇 |
1979年 | 11篇 |
1972年 | 14篇 |
1971年 | 19篇 |
1970年 | 10篇 |
1969年 | 10篇 |
1968年 | 20篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
Paolo Calabresi Emesto Fedele Antonio Pisani Giovanni Fontana Nicola B. Mercuri Giorgio Bernardi Maurizio Raiteri 《The European journal of neuroscience》1995,7(9):1889-1894
Using a corticostriatal slice preparation, we have recently shown that tetanic stimulation of the corticostriatal pathway produces long-term depression (LTD) of striatal excitatory synaptic transmission. In the present study we have analysed the relationship between LTD and the striatal release of different endogenous transmitters. Samples of perfusate were collected via a small cannula placed just above the surface of the striatal slice close to the recording electrode, and were analysed by HPLC. The high-frequency stimulation (100 Hz, three trains, 3 s duration, 20 s intervals) used to induce LTD caused a significant but transient increase in the release of both excitatory (aspartate and glutamate) and inhibitory (glycine and GABA) amino acid transmitters. Tetanic stimulation also produced a significant, but transient increase in the release of endogenous dopamine. We conclude that the tetanic stimulation of the corticostriatal pathway is able to induce a large but transient release of excitatory amino acids and of dopamine, whose participation in the induction of striatal LTD has been demonstrated previously. Moreover, the maintenance of this form of synaptic plasticity does not seem to require a sustained change in transmitter release. 相似文献
22.
23.
24.
Antonio Giorgio M.D. Luciano Tarantino Giampiero Francica Nicola Mariniello Antonio Nuzzo Luca del Viscovo Antonio Rotondo 《Cardiovascular and interventional radiology》1996,19(1):27-31
Purpose: To verify the efficacy of ultrasound (US)-guided injection of large amounts of ethanol into large or multiple liver lesions,
in a single session under general anesthesia (one-shot PEI) for percutaneous ablation of hepatic tumors.
Methods: Twenty-nine patients (27 with 51 hepatocellular carcinoma (HCC) nodules on cirrhosis, diameter range 1.0<+>–<+>9.0 cm; two
patients with a single metastasis from the gastroenteric tract, 5.0 and 9.0 cm, respectively, in diameter) were treated with
one-shot PEI.
Results: The total volume of alcohol delivered per patient ranged from 16 to 210 ml. Mean ethanol volume in all patients was 49 ml.
Dynamic computed tomography (CT) examination showed complete necrosis in 41 of 50 lesions. Two patients died of hypovolemic
shock due to massive upper gastrointestinal bleeding, 3 and 7 days, respectively, after the interventional procedure. All
the remaining patients are alive (follow-up 5<+>–<+>14 months) except one who died of liver failure 5 months after. New HCC
nodules occurred in six patients within 6 months and one intralesional relapse was recorded.
Conclusion: In this preliminary experience, one-shot PEI is as effective in inducing liver tumor necrosis as traditional PEI; its advantages
are shorter treatment time and the capability of treating larger and multiple liver lesions. 相似文献
25.
26.
Salvatore Metafora Gianfranco Peluso Gianpietro Ravagnan Magda Marchese Michele di Pietro Aldo Mancini Nicola Panza Antonio Fusco Raffaele Porta 《Medical oncology (Northwood, London, England)》1988,5(4):223-231
Transglutaminase (TGase) activity was reduced in intact mitogen-stimulated human peripheral blood lymphocytes (PBL) when compared to intact resting PBL. Moreover, a treatment of the same quiescent immunocompetent cells with purified liver TGase and Ca2+ completely suppressed the mitogen-induced blast transformation. A decrease in TGase activity in neoplastically transformed seminal vesicle epithelial cells with respect to their normal parent counterpart was also observed. Our data support the notion of a possible implication of TGase in cell proliferation and transformation. 相似文献
27.
A novel role for shuttling SR proteins in mRNA translation 总被引:15,自引:1,他引:15
28.
29.
30.