全文获取类型
收费全文 | 1631篇 |
免费 | 168篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 118篇 |
妇产科学 | 11篇 |
基础医学 | 209篇 |
口腔科学 | 15篇 |
临床医学 | 162篇 |
内科学 | 442篇 |
皮肤病学 | 9篇 |
神经病学 | 187篇 |
特种医学 | 170篇 |
外科学 | 127篇 |
综合类 | 30篇 |
一般理论 | 1篇 |
预防医学 | 114篇 |
眼科学 | 88篇 |
药学 | 71篇 |
肿瘤学 | 41篇 |
出版年
2021年 | 13篇 |
2018年 | 20篇 |
2017年 | 24篇 |
2016年 | 17篇 |
2015年 | 26篇 |
2014年 | 34篇 |
2013年 | 50篇 |
2012年 | 51篇 |
2011年 | 55篇 |
2010年 | 52篇 |
2009年 | 54篇 |
2008年 | 52篇 |
2007年 | 53篇 |
2006年 | 30篇 |
2005年 | 34篇 |
2004年 | 48篇 |
2003年 | 46篇 |
2002年 | 32篇 |
2001年 | 42篇 |
2000年 | 42篇 |
1999年 | 42篇 |
1998年 | 39篇 |
1997年 | 33篇 |
1996年 | 34篇 |
1995年 | 35篇 |
1994年 | 35篇 |
1993年 | 26篇 |
1992年 | 26篇 |
1991年 | 34篇 |
1990年 | 27篇 |
1989年 | 35篇 |
1988年 | 39篇 |
1987年 | 49篇 |
1986年 | 40篇 |
1985年 | 41篇 |
1984年 | 29篇 |
1983年 | 33篇 |
1982年 | 42篇 |
1981年 | 28篇 |
1980年 | 24篇 |
1979年 | 18篇 |
1978年 | 18篇 |
1977年 | 19篇 |
1976年 | 22篇 |
1975年 | 19篇 |
1974年 | 13篇 |
1973年 | 22篇 |
1972年 | 17篇 |
1971年 | 15篇 |
1970年 | 13篇 |
排序方式: 共有1801条查询结果,搜索用时 15 毫秒
61.
Ohne Zusammenfassung 相似文献
62.
T. Tadmor J. Bejar D. Attias E. Mischenko E. Sabo G. Neufeld Z. Vadasz 《American journal of hematology》2013,88(5):355-358
Myeloproliferative neoplasms (MPNs) are malignant disorders originating from clonal expansion of a single neoplastic stem cell and characteristically show an increase in bone marrow reticulin fibers. Lysyl oxidases (LOXs) are copper‐dependent amine oxidases that play a critical role in the biogenesis of connective tissue by crosslinking extracellular matrix proteins, collagen and elastin. Expression of LOX gene family members is increased in disorders associated with increased fibrosis. To evaluate involvement of LOX gene family in various MPNs. In‐situ hybridization was used to detect Lysyl‐Oxidase family members in bone marrow biopsies from patients with different MPNs. We compared normal bone marrows and those from patients with polycythemia vera, essential thrombocythemia, chronic myeloid leukemia, and primary myelofibrosis (PMF). Serum levels of lysyl‐oxidase from patients with PMF and healthy controls were also examined. LOX gene family was not detected in normal bone marrows. All members of the LOX gene family were over expressed in PMF. In other MPNs a differential pattern of expression was observed. Differences in gene expression were statistically significant (P < 0.010). The medianserum LOX levels in normal controls was 28.4 ± 2.5 ng\ml and 44.6 ± 9.44 ng\ml in PMF (P = 0.02). The varying pattern of expression of LOX genes may reflect differences in the pathophysiology of bone marrow fibrosis in these MPNs. These observations could be used as the basis for future targeted therapy directed against bone marrow fibrosis. Am. J. Hematol. 88:355–358, 2013. © 2013 Wiley Periodicals, Inc. 相似文献
63.
64.
65.
66.
67.
68.
69.
EJ Horn S Domm HI Katz M Lebwohl U Mrowietz K Kragballe for the International Psoriasis Council 《Journal of the European Academy of Dermatology and Venereology》2010,24(2):119-124
Corticosteroids are a mainstay of topical therapy for psoriasis. While efficacious and relatively safe when used carefully, the potential for side effects, notably skin atrophy and adrenal suppression, have been associated with excesses in potency, prolonged or widespread use. The International Psoriasis Council Working Group on Topical Therapy has reviewed the efficacy and safety of topical corticosteroids and recommends strategies for safe, long‐term use of these agents. 相似文献
70.
Felicia Trachtenberg Dru Foote Marie Martin Susan Carson Thomas Coates Owen Beams Olivia Vega Manuela Merelles‐Pulcini Patricia J. Giardina Dorothy A. Kleinert Janet Kwiatkowski Alexis A. Thompson Ellis J. Neufeld Leann Schilling Vivek Thayalasuthan Zahra Pakbaz Robert Yamashita For The Thalassemia Clinical Research Network 《American journal of hematology》2010,85(5):367-370