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521.
Ryan S. Cousins David J. Dexter Sadaf S. Ahanchi Brandon C. Cain Obie M. Powell Sarah B. Ongstad Niraj M. Parikh Jean M. Panneton 《Journal of vascular surgery》2018,67(3):838-847
Objective
The objective of this study was to determine the natural progression of popliteal artery aneurysms (PAAs) and clinical variables associated with their accelerated growth.Methods
Retrospective chart review of 224 patients with encounters between January 2008 and May 2016 and with at least one PAA was conducted. From this group, 65 asymptomatic patients had either unilateral (n = 43) or bilateral (n = 22) PAAs that were observed for at least 1 year of medical management before intervention. We divided these aneurysms into two groups based on whether their overall growth rate was above or below the eventual mean. Aneurysm diameter was taken from duplex ultrasound and computed tomography angiography.Results
There were 87 aneurysms evaluated among 65 patients. Mean age at diagnosis was 70.9 years (standard deviation [SD], 9.39 years), and 64 patients were male (98%); 50 (77%) were white and 7 (11%) were African American. The average body mass index was 27.69 (SD, 4.90). At or before initial diagnosis, 61 (94%) patients had a concomitant lower extremity or abdominal aortic aneurysm; 51 (78%) patients were current or former smokers; and 16 (25%) had atrial fibrillation. The average growth rate of all aneurysms was 1.22 mm/y (SD, 1.93 mm). The mean surveillance time from initial diagnosis to last follow-up or intervention was 3.12 years (SD, 1.66 years). Of 87 aneurysms, 25 (29%) were repaired; 18 (21%) were repaired because of size criteria, 2 (2%) because of symptom criteria (claudication or acute limb ischemia), and 5 (6%) because of both criteria. During our study window, 62 aneurysms (71%) remained asymptomatic or did not undergo an intervention. The mean initial diameter at diagnosis was 16.9 mm (SD, 5.32 mm). Within the study, 50 (57%) aneurysms presented with or developed mural thrombus. Univariate analysis identified larger initial diameter (19.2 vs 14.7 mm; P = .020), atrial fibrillation (35% vs 16%; P = .042), and mural thrombus (38% vs 20%; P < .001) as predictors of diameter expansion greater than the mean. Multivariable analysis of the significant univariate factors determined that only initial diameter (odds ratio, 5.53; P = .007) and the presence or development of mural thrombus (odds ratio, 4.00; P = .008) maintained significance.Conclusions
Patients presenting with a PAA at 20 mm or >20 mm in diameter, presence of luminal thrombus, or atrial fibrillation may need to be observed at more frequent scanning intervals than those without these risk factors. Further studies are required to validate these predictive growth factors. 相似文献522.
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Nazia Parveen Saeed Ronney Bernardes Panerai Thompson Gordon Robinson 《Ultrasound in medicine & biology》2013
Temporal insonation is not always possible for the middle cerebral artery (MCA) for blood flow velocity (BFV) measurements, to estimate cerebral autoregulation. We compared BFV and cerebral autoregulation estimates from the common-carotid (CCA) and internal-carotid arteries (ICA) with the MCA. BFV was measured at the CCA, ICA and MCA, synchronously with blood pressure, heart rate and end-tidal CO2 and was recorded onto a data acquisition system. The autoregulation index (ARI) estimated using the Tiecks model. Eleven healthy volunteers (7 women, 33 ± 9 years old) were recruited. BFVs in the MCA, CCA and ICA were 60.3 ± 8.9, 64.4 ± 6.5 and 69.2 ± 4.8 cm/s, respectively. ARI estimates were not significantly different (5.6 ± 0.8, 6.0 ± 1.1 and 5.9 ± 0.5, respectively). Good reproducibility over repeated measurements was evidenced by low coefficient of variation of standard error of measurement for BFV and ARI. The CCA and ICA are alternatives to the MCA, where insonation is impossible, because of an absent trans-temporal window or where it cannot be tolerated, such as in patients with head injury. 相似文献
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Suhail Amin Patigaroo Nazia Mehfooz Fozia Amin Patigaroo Masood H. Kirmani Arafat Waheed Shakura Bhat 《European archives of oto-rhino-laryngology》2012,269(7):1747-1754
The aims of the article were to study the clinical characteristic of patients with pseudocysts and to compare different common modalities of treatment and introduce the concept of observation in pseudocyst management. Twenty-eight patients were diagnosed with pseudocyst of the auricle between June 2009 and June 2011 in a medical college hospital. The patients were divided into four groups each of seven patients on the basis of primary treatment offered. Four primary treatments offered were simple aspiration, aspiration with intralesional steroid, incision and drainage with removal of anterior cartilage leaflet with buttoning, and lastly, simple observation and reassurance. All 28 patients were male with involvement of right side more than left and no one had bilateral involvement. Adults in the age group of 30–40 were commonly affected. Most of the patients had history of significant trauma by security forces. Most common site of involvement was scaphoid and triangular fossa. The best form of treatment with minimum recurrence was incision and drainage with removal of anterior cartilage leaflet with buttoning. Simple observation as a treatment option was found to be as good as intralesional steroids. Pseudocyst of the pinna is a benign condition of unknown etiology affecting the pinna, commonly encountered in middle-aged men. It is a rare condition and is hardly encountered in routine ENT practice. Bilateral diseases are uncommon. Most common site of occurrence is triangular and scaphoid fossa. Many modalities of treatment have been recommended in literature with varied recurrence and failure rates. The best treatment is surgical deroofing followed by buttoning with minimum recurrences. An option of simple observation for 2–3?months should be discussed with each patient and was found to be as good as intralesional steroids. 相似文献
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