Combined use of tuberculin and hydrocortisone in the complex treatment of pulmonary tuberculosis

The paper deals with the results of treatment of 50 active pulmonary tuberculosis patients who at the early terms were given tuberculin in combination with hydrocortisone phonophoresis locally applied on the lesion. The method effectiveness rises in closure of destruction cavities. Tuberculin has an immunomodulatory action and stimulates antibody formation.     

Disturbances and restoration of function in the hind legs of puppies following deafferentation

Summary Long-term experiments were performed on puppies, aged 2–4 months, in which the left hind leg was deafferentated.This operation was performed by the section of the posterior roots and extirpation of the spinal ganglia. The number of roots which were divided varied from 3 to 8. It was established that deafferentation caused deep disturbances of the locomotor function and sensitivity of the deafferentated extremity both in puppies and in adult dogs. This differed from manifestations caused by affection of the Interocentral paths.Presented by Active Member Acad. Med. Sci. USSR V.V. Parin     

Effect of catecholaminergic drugs on systems of reward and punishment in experiments on cats

Injection of amantadine or DOPA produced inhibition of both self-stimulation and negative-reinforcing effects of stimulation of the hypothalamus. After injections of 1-DOPA in cats pretreated with Ro 4-4602, an inhibitor of peripheral decarboxylase, or disulfiram, a dopamine-β-hydroxylase inhibitor, the inhibitory action on the reinforcing system was enhanced. Amphetamine activated both reward and punishment systems. This data supports an inhibitory function of dopamine in systems of reinforcement and of an activating function of noradrenaline in these systems.