利用Server-U实现校园网数据的异地备份

阐述了校园网数据异地备份的必要性，在分析常见数据存贮及备份方法的基础上，构建了利用Server-U实现校园网数据异地备份的应用系统。同时指出该系统具有操作方便、运行稳定、容错性好等优点，能较好实现对校园网应用服务器数据的异地备份。     

放射治疗肺癌脊椎转移的临床研究

为探讨肺癌脊柱转移放射治疗的时间剂量分割方法及其疗效,将肺癌脊柱转移64例患者随机分为治疗组和对照组,治疗组每次3Gy,每周5次,共30Gy;对照组每次2Gy,每周5次,共50Gy;两组均使用6mVX线照射.分别比较疼痛缓解率、止痛起效时间、及脊髓压迫缓解率.结果显示治疗组和对照组的疼痛缓解率分别为87.5%和81.3%,无显著性差异(P＞0.05);平均止痛起效时间分别为8±2.2天和15±3.2天,差异性显著(P＜0.01);脊髓压迫缓解率分别为85.0%和81.8%,无显著性差异(P＞0.05).结果表明放射治疗肺癌脊柱转移疗效好,起效快,建议使用30Gy/10f/2W的时间剂量分割模式.     

Acute ischemia of the hand as a complication of radial artery catheterization. Apropos of 2 cases following abdominal sarcoma surgery

Arterial catheterization is a simple technique that yields great benefits, such as continuous monitoring of arterial pressure and the possibility of taking repeated samples for analysis. However, it is not free of complications, the main ones being limb ischemia and gas embolism. To reduce the risk of complications, guidelines for insertion and maintenance of arterial catheters have been established. We report two cases of acute hand ischemia secondary to arterial catheterization. Both patients were undergoing surgery for sarcoma-type abdominal cancer and developed acute ischemia of the hand lasting several hours. The predisposing factor in both cases was the existence of a highly advanced sarcoma-type abdominal tumor, probably related to a state of hypercoagulability.     

宫颈癌细胞中与UTF1相互作用的蛋白分析

【摘要】目的 探讨宫颈癌细胞中与转录辅激活因子（UTF1）相互作用的蛋白。方法 构建稳定表达FLAG HA 双标签标记的UTF1蛋白的SiHa 细胞株,利用FLAG HA 串联亲和纯化( TAP) 双标签纯化实验,对目的条带进行质谱分析。结果 成功构建稳定表达FLAG HA 双标签标记的UTF1 细胞株。通过质谱分析得到UTF1相互作用的蛋白数据,结果显示UTF1 捕获蛋白参与DNA修复、代谢、核糖体、细胞连接、细胞因子相互作用、吞噬等多种生物学过程,以及Jak STAT、MAPK、mTOR、VEGF、 wnt 等多条信号通路,并与系统性红斑狼疮、帕金森症、阿尔兹海默症、自身免疫性疾病等的发病相关。结论 UTF1 捕获蛋白参与细胞多种生理及病理过程,为进一步了解UTF1在肿瘤发病机制中的作用提供了新的线索。     

Assessment of optic nerve and optic tract alterations in patients with orbital space-occupying lesions using probabilistic diffusion tractography

AIM: To investigate the diffusion changes in both the optic nerve and optic tract in orbital space-occupying lesion patients with decreased visual acuity, and its clinical significance using probabilistic diffusion tractography (PDT). METHODS: Twenty patients with orbital space-occupying lesions and 25 age- and gender-matched healthy persons were included. All patients and controls underwent routine orbital magnetic resonance imaging and diffusion tensor imaging (DTI), using a 3.0T magnetic resonance scanner (Trio Tim Siemens). After the image data were preprocessed, each DTI parameters of the optic nerve and optic tract was obtained by PDT, including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD). The asymmetry index (AI) of each parameter was calculated. Compared the parameters of the affected side optic nerve and ipsilateral optic tract with the contralateral side by paired sample t-test; compared AI of parameters of optic nerve and optic tract between the patient group and the control group by independent sample t-test. Patients were divided into three subgroups according to the low vision grade standard of WHO, compared the FA and AI of FA between the three subgroups by single factor variance analysis. RESULTS: The affected side optic nerve presented significantly decreased FA, increased MD, AD, and RD values compared to the unaffected side (P<0.05). The AI of FA, MD, AD, and RD of optic nerve in the patients was significantly higher than that of the controls (P<0.05). The comparison results of the optic tract showed that there was no significant difference between the patient group and control group in terms of the bilateral optic tracts in patients (P>0.05). The AIs of the FA value of the optic nerve in the eyesight <0.1 subgroup was significantly higher than that in the other groups (P<0.05). CONCLUSION: FA, MD, AD, and RD of the affected side optic nerve of the orbital space-occupying lesions have significantly changed, the FA value is the most sensitive. The PDT could be a useful tool to provide valid quantitative markers of optic nerve injuries and evaluate the severity of orbital diseases, which other examinations cannot be acquired.     

缺氧缺血性脑病79例临床分析

目的总结分析新生儿缺氧缺血性脑病(HIE)发病的相关因素及临床特征。方法对79例临床诊断为HIE新生儿的发病相关因素、CT表现等进行分析。结果羊水污染占56%,胎膜早破占42%,脐带绕颈占39%,妊高征占30%,母贫血占13%,其中存在两种因素占30%。全部病例中CT检查76例有异常表现,阳性率96%,合并蛛网膜下腔出血占61%,合并脑室出血占15%,脑室内出血羊水Ⅲ度污染占58%,重度窒息占67%,分析颅内出血的发病因素,其中有两种异常因素占50%。早产儿有71%存在脑室内出血。结论羊水污染是HIE发生的首要因素,脑室出血与羊水Ⅲ度污染及重度窒息关系密切,早产儿易合并脑室出血。要加强围产期预防,对产科异常因素,临床有症状的新生儿,颅脑CT应作为常规检查手段。     

失效模式与效应分析在低能X线术中放疗的应用

目的:探讨失效模式与效应分析(FMEA)在低能X线术中放疗(IORT)中的应用,分析其在IORT中的潜在风险,初步探讨FMEA优化IORT管理、减少潜在风险发生的可行性。方法:由IORT团队(1名放疗科医生、1名放疗科物理师、2名外科医生、2名护士)成立FMEA工作小组,应用FMEA方法开展系统风险评估。确立流程模块,...