全文获取类型
收费全文 | 618篇 |
免费 | 33篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 30篇 |
妇产科学 | 1篇 |
基础医学 | 52篇 |
口腔科学 | 33篇 |
临床医学 | 56篇 |
内科学 | 124篇 |
皮肤病学 | 17篇 |
神经病学 | 16篇 |
特种医学 | 99篇 |
外科学 | 61篇 |
综合类 | 24篇 |
预防医学 | 34篇 |
眼科学 | 21篇 |
药学 | 72篇 |
中国医学 | 1篇 |
肿瘤学 | 15篇 |
出版年
2021年 | 16篇 |
2020年 | 4篇 |
2019年 | 1篇 |
2018年 | 7篇 |
2017年 | 4篇 |
2016年 | 11篇 |
2015年 | 11篇 |
2014年 | 12篇 |
2013年 | 28篇 |
2012年 | 28篇 |
2011年 | 14篇 |
2010年 | 31篇 |
2009年 | 30篇 |
2008年 | 14篇 |
2007年 | 16篇 |
2006年 | 28篇 |
2005年 | 15篇 |
2004年 | 12篇 |
2003年 | 21篇 |
2002年 | 19篇 |
2001年 | 13篇 |
2000年 | 12篇 |
1999年 | 23篇 |
1998年 | 35篇 |
1997年 | 25篇 |
1996年 | 22篇 |
1995年 | 13篇 |
1994年 | 22篇 |
1993年 | 25篇 |
1992年 | 7篇 |
1991年 | 6篇 |
1990年 | 5篇 |
1989年 | 13篇 |
1988年 | 15篇 |
1987年 | 9篇 |
1986年 | 14篇 |
1985年 | 7篇 |
1984年 | 8篇 |
1983年 | 6篇 |
1982年 | 9篇 |
1981年 | 12篇 |
1980年 | 12篇 |
1978年 | 4篇 |
1977年 | 5篇 |
1976年 | 9篇 |
1975年 | 2篇 |
1974年 | 1篇 |
1957年 | 1篇 |
1955年 | 1篇 |
排序方式: 共有658条查询结果,搜索用时 8 毫秒
601.
Mice lacking both macrophage- and granulocyte-macrophage colony- stimulating factor have macrophages and coexistent osteopetrosis and severe lung disease 总被引:11,自引:5,他引:6
Lieschke GJ; Stanley E; Grail D; Hodgson G; Sinickas V; Gall JA; Sinclair RA; Dunn AR 《Blood》1994,84(1):27-35
Mice deficient in granulocyte-macrophage colony-stimulating factor (GM- CSF) and macrophage colony-stimulating factor (M-CSF, CSF-1) were generated by interbreeding GM-CSF-deficient mice generated by gene targeting (genotype GM-/-) with M-CSF-deficient osteopetrotic mice (genotype M-/-, op/op). Mice deficient in both GM-CSF and M-CSF (genotype GM-/-M-/-) are viable and have coexistent features corresponding to mice deficient in either factor alone. Like M-CSF- deficient mice, they have osteopetrosis and are toothless because of failure of incisor eruption. Like GM-CSF-deficient mice, they have a characteristic alveolar-proteinosis-like lung pathology, but it is more severe than that of GM-CSF-deficient mice and is often fatal. In particular, in GM-/-M-/- mice the accumulation of lipo-proteinaceous alveolar material is more marked, and bacterial pneumonic infections are more prevalent and more extensive, particularly involving Gram- negative bacteria. Neutrophilia consistently accompanies pulmonary infections, and some older GM-/-M-/- mice have polycythemia. Survival of GM-/-M-/- mice is significantly reduced compared with mice deficient in either factor alone, and all GM-/-M-/- mice have broncho- or lobar- pneumonia at death. These observations indicate that in vivo, M-CSF is involved in modulating the consequences of GM-CSF deficiency in the lung. Interestingly, GM-/-M-/- mice have circulating monocytes at levels comparable with those in M-CSF-deficient mice and the diseased lungs of all GM-/-M-/- mice contain numerous phagocytically active macrophages, indicating that in addition to GM-CSF and M-CSF, other factors can be used for macrophage production and function in vivo. 相似文献
602.
603.
604.
605.
606.
Robert AR Bywater Nick J. Spencer Rose Fida Grahame S. Taylor 《Clinical and experimental pharmacology & physiology》1998,25(10):857-861
1. Movements of the gastrointestinal tract are required for the digestion of food and the expulsion of waste products. 2. The present paper will discuss the nature of electrical rhythms underlying some intestinal motility patterns. 3. The rhythms are generated by pacemakers with cycle rates appropriate to controlling individual contractions, motor pat-ternings or switching between different motor programmes. 4. Electrical rhythms are discussed with periods of the order of seconds, minutes and hours. 5. Particular discussion is centred on rhythms recorded from the small and large intestine of the mouse. 相似文献
607.
608.
609.
Neonatal ovarian cysts: sonographic-pathologic correlation 总被引:4,自引:0,他引:4
The authors reviewed the prenatal (11 infants) and postnatal (17 infants) sonograms and the clinical, surgical, and pathologic findings in 17 infants with an ovarian cyst to determine the sonographic features and natural history of neonatal ovarian cysts. An uncomplicated cyst (nontwisted, nonhemorrhagic) was completely anechoic and the cyst wall was imperceptible with sonography (five cases). A twisted or hemorrhagic cyst was cystic with a fluid-debris level, cystic with a retracting clot, septated with or without internal echoes, or solid (12 cases). These complicated cysts contained liquid and/or organized hematoma. Eleven of the 12 complicated cysts had a thin, highly echogenic wall. Cyst torsion commonly occurred in utero and could be diagnosed on prenatal sonograms by a typical sonographic appearance (eight cases). All of these infants were asymptomatic after birth. Four infants with hemorrhagic or twisted cysts were symptomatic. All cysts except one that resolved spontaneously were treated surgically, including three twisted cysts that showed no change in size over a 1-8-month interval. All of the cysts were of follicular origin. 相似文献
610.