全文获取类型
收费全文 | 96篇 |
免费 | 7篇 |
国内免费 | 2篇 |
专业分类
儿科学 | 7篇 |
基础医学 | 9篇 |
口腔科学 | 5篇 |
临床医学 | 12篇 |
内科学 | 15篇 |
皮肤病学 | 8篇 |
神经病学 | 1篇 |
特种医学 | 24篇 |
外科学 | 13篇 |
综合类 | 5篇 |
预防医学 | 2篇 |
眼科学 | 1篇 |
药学 | 1篇 |
肿瘤学 | 2篇 |
出版年
2021年 | 1篇 |
2020年 | 1篇 |
2019年 | 4篇 |
2018年 | 4篇 |
2017年 | 1篇 |
2016年 | 3篇 |
2015年 | 4篇 |
2013年 | 6篇 |
2012年 | 3篇 |
2011年 | 2篇 |
2010年 | 7篇 |
2009年 | 8篇 |
2008年 | 1篇 |
2007年 | 2篇 |
2006年 | 1篇 |
2005年 | 1篇 |
2004年 | 7篇 |
2003年 | 3篇 |
2002年 | 2篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1998年 | 3篇 |
1997年 | 2篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1994年 | 3篇 |
1993年 | 2篇 |
1992年 | 1篇 |
1990年 | 1篇 |
1989年 | 2篇 |
1988年 | 3篇 |
1987年 | 3篇 |
1986年 | 2篇 |
1985年 | 3篇 |
1984年 | 2篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1981年 | 2篇 |
1980年 | 3篇 |
1979年 | 2篇 |
1976年 | 1篇 |
1975年 | 1篇 |
排序方式: 共有105条查询结果,搜索用时 15 毫秒
71.
72.
73.
74.
Release of cytokines, soluble cytokine receptors, and interleukin-1 receptor antagonist after intravenous immunoglobulin administration in vivo 总被引:6,自引:3,他引:6
Aukrust P; Froland SS; Liabakk NB; Muller F; Nordoy I; Haug C; Espevik T 《Blood》1994,84(7):2136-2143
We investigated the in vivo effects of one bolus injection (400 mg/kg) of intravenous immunoglobulin (IVIG) on a number of cytokines, soluble cytokine receptors, and interleukin-1 receptor antagonist (IL-1Ra) in plasma in 12 patients with primary hypogammaglobulinemia. A significant and rapid increase in plasma levels of IL-6, IL-8, and tumor necrosis factor alpha (TNF alpha) was seen within 1 hour after IVIG infusion. This increase was accompanied by a more prolonged elevation in levels of both types of soluble TNF receptors (sTNFRs), which remained elevated throughout the study period (44 hours) although they reached peak levels within 1 hour. After an initial increase in the ratio between TNF alpha and sTNFRs, this ratio decreased to values significantly lower than baseline values 20 and 44 hours postinfusion with approximately 600-fold molar excess of sTNFRs to TNF alpha (trimer). Although only a modest but statistically significant increase in plasma levels of IL-1 beta was seen, IVIG infusion was followed by a marked increase in plasma levels of IL-1Ra with 1,000-fold molar excess of IL-1Ra to IL-1 beta in some patients. The demonstrated effects of IVIG infusion on the cytokine network, particularly the induction of IL- 1Ra and sTNFRs release, might be important for the therapeutic effects of IVIG in several immune-mediated disorders. 相似文献
75.
Yajnesh Kidiyoor MBBS Post Graduate Student Vinod C. Nayak MD Assistant Professor Vasudha Devi MD Assistant Professor Shankar M. Bakkannavar MD Assistant Professor G. Pradeep Kumar MD Professor Head Ritesh G. Menezes MD Diplomate NB Assistant Professor 《Journal of Forensic and Legal Medicine》2009,16(8):472-474
Organophosphorus poisoning occurs very commonly in southern India where farmers form a significant proportion of the population who commonly use organophosphorus compounds like parathion as insecticides. Awareness of the complications caused by parathion poisoning is essential for proper monitoring and treatment. We report a case of suicidal parathion poisoning in a farmer who was treated with atropine and oximes. He subsequently developed myocardial infarction, to the treatment of which, he showed no response and succumbed. In conclusion, myocardial infarction is a rare complication of parathion poisoning. Awareness of this complication of parathion poisoning, proper monitoring and treatment could prevent fatalities. 相似文献
76.
77.
NB Sánchez IF Canedo PE García-Patos P de Unamuno Pérez AV Benito AM Pascual 《Journal of the European Academy of Dermatology and Venereology》2004,18(6):731-735
The association between vasculitis and cancer has been widely reviewed in recent decades. The existence of malignancies in patients with vasculitis has been estimated at about 4.5-8%, haematological neoplasms being the most frequently observed. The haematological malignancies most frequently described are lymphoproliferative diseases such as hairy cell leukaemia and lymphomas. On the contrary, the incidence of paraneoplastic vasculitis in patients with myeloma is low; up to now, we have found nine cases reported on this subject. We report the case of a 73-year-old woman who in 1 year showed three outbreaks of acutely painful, purpuric and ulceronecrotic lesions, localized on the lower extremities. Histopathological study demonstrated thrombosis in the arterioles and leucocytoclastic vasculitis. Complementary tests revealed the presence of multiple myeloma. 相似文献
78.
79.
80.
Wings TY Loo Lijian Jin Mary NB Cheung Min Wang Louis WC Chow 《Journal of translational medicine》2010,8(1):110