Lexical attrition in younger and older bilingual adults

Healthy monolingual older adults experience changes in their lexical abilities. Bilingual individuals immersed in an environment in which their second language is dominant experience lexical changes, or attrition, in their first language. Changes in lexical skills in the first language of older individuals who are bilinguals, therefore, can be attributed to the typical processes accompanying older age, the typical processes accompanying first-language attrition in bilingual contexts, or both. The challenge, then, in understanding how lexical skills change in bilingual older individuals, lies in dissociating these processes. This paper addresses the difficulty of teasing apart the effects of ageing and attrition in older bilinguals and proposes some solutions. It presents preliminary results from a study of lexical processing in bilingual younger and older individuals. Processing differences were found for the older bilingual participants in their first language (L1), but not in their second language (L2). It is concluded that the lexical behaviour found for older bilinguals in this study can be attributed to L1 attrition and not to processes of ageing. These findings are discussed in the context of previous reports concerning changes in lexical skills associated with typical ageing and those associated with bilingual L1 attrition.     

Spread of Cryptococcus gattii into Pacific Northwest Region of the United States

Cryptococcus gattii has emerged as a human and animal pathogen in the Pacific Northwest. First recognized on Vancouver Island, British Columbia, Canada, it now involves mainland British Columbia, and Washington and Oregon in the United States. In Canada, the incidence of disease has been one of the highest worldwide. In the United States, lack of cryptococcal species identification and case surveillance limit our knowledge of C. gattii epidemiology. Infections in the Pacific Northwest are caused by multiple genotypes, but the major strain is genetically novel and may have emerged recently in association with unique mating or environmental changes. C. gattii disease affects immunocompromised and immunocompetent persons, causing substantial illness and death. Successful management requires an aggressive medical and surgical approach and consideration of potentially variable antifungal drug susceptibilities. We summarize the study results of a group of investigators and review current knowledge with the goal of increasing awareness and highlighting areas where further knowledge is required.     

Effects of hydrostatic pressure on sensory discharge in frog semicircular canals.

The effects of endolymphatic and perilymphatic pressure changes on resting and mechanically evoked responses were studied in isolated posterior semicircular canals of the frog. The results demonstrated that ampullar receptors are extremely sensitive to hydrostatic pressure changes (0.25 mm H2O were sufficient to produce distinct changes), being inhibited by endolymphatic pressure increases and facilitated by perilymphatic ones. Intracellular recordings from single afferent axons showed that the effects of hydrostatic pressure result from a modified transmitter release from the synaptic pole of the hair cells. Unlike resting activity, mechanically evoked activity was always depressed in the presence of a hydrostatic pressure. This indicates that the sensitivity of ampullar receptors to mechanical stimuli, i.e. the gain of the conversion process, is maximal when no pressure is present between the inner and the outer fluid. The possible action of hydrostatic pressure on vestibular receptors is discussed.     

Education in stroke: strategies to improve stroke patient care

'Stroke units save lives', but organized care requires expert staff and regular training to be effective. However, the quality of inpatient care for stroke remains poor, and stroke education is often fragmented between the health-care professions. This review describes some national and local strategies aimed at ensuring that all patients are cared for by expert staff.