全文获取类型
收费全文 | 5010篇 |
免费 | 200篇 |
国内免费 | 33篇 |
专业分类
耳鼻咽喉 | 19篇 |
儿科学 | 128篇 |
妇产科学 | 44篇 |
基础医学 | 700篇 |
口腔科学 | 35篇 |
临床医学 | 314篇 |
内科学 | 1643篇 |
皮肤病学 | 44篇 |
神经病学 | 400篇 |
特种医学 | 160篇 |
外科学 | 782篇 |
综合类 | 35篇 |
预防医学 | 135篇 |
眼科学 | 19篇 |
药学 | 241篇 |
中国医学 | 22篇 |
肿瘤学 | 522篇 |
出版年
2023年 | 21篇 |
2022年 | 48篇 |
2021年 | 67篇 |
2020年 | 40篇 |
2019年 | 48篇 |
2018年 | 50篇 |
2017年 | 62篇 |
2016年 | 59篇 |
2015年 | 69篇 |
2014年 | 125篇 |
2013年 | 128篇 |
2012年 | 213篇 |
2011年 | 278篇 |
2010年 | 160篇 |
2009年 | 143篇 |
2008年 | 253篇 |
2007年 | 316篇 |
2006年 | 313篇 |
2005年 | 327篇 |
2004年 | 355篇 |
2003年 | 320篇 |
2002年 | 342篇 |
2001年 | 119篇 |
2000年 | 109篇 |
1999年 | 130篇 |
1998年 | 129篇 |
1997年 | 116篇 |
1996年 | 79篇 |
1995年 | 79篇 |
1994年 | 75篇 |
1993年 | 68篇 |
1992年 | 61篇 |
1991年 | 42篇 |
1990年 | 44篇 |
1989年 | 46篇 |
1988年 | 53篇 |
1987年 | 35篇 |
1986年 | 26篇 |
1985年 | 22篇 |
1984年 | 25篇 |
1983年 | 22篇 |
1982年 | 13篇 |
1981年 | 19篇 |
1980年 | 13篇 |
1978年 | 18篇 |
1977年 | 9篇 |
1976年 | 11篇 |
1975年 | 14篇 |
1934年 | 8篇 |
1932年 | 8篇 |
排序方式: 共有5243条查询结果,搜索用时 15 毫秒
81.
Zusammenfassung Das Lyssavirus, das mit Ultraschallwellen inaktiviert wurde, erzeugt bei intraspinaler Injektion an Kaninchen eine Immunitätskraft gegen Wutvirus. Ausführliche Mitteilung wird in einer Fachzeitschrift erscheinen. 相似文献
82.
Prof. Dr. Michio Kasahara Yoshito Nishizawa Hitoshi Horie Shigeo Hirao 《Journal of molecular medicine (Berlin, Germany)》1938,17(36):1260-1263
Ohne Zusammenfassung 相似文献
83.
84.
Tomoki Kuge Kiyoharu Fukushima Yuki Matsumoto Haruko Saito Yuko Abe Eri Akiba Kako Haduki Tadayoshi Nitta Akira Kawano Michio Tanaka Yumi Hattori Takahiro Kawasaki Takanori Matsuki Takayuki Shiroyama Daisuke Motooka Kazuyuki Tsujino Keisuke Miki Masahide Mori Seigo Kitada Shota Nakamura Tetsuya Iida Atsushi Kumanogoh Hiroshi Kida 《Emerging infectious diseases》2022,28(7):1437
Unidentified Mycobacterium species are sometimes detected in respiratory specimens. We identified a novel Tsukamurella species (Tsukamurella sp. TY48, RIMD 2001001, CIP 111916T), Tsukamurella toyonakaense, from a patient given a misdiagnosis of nontuberculous mycobacterial pulmonary disease caused by unidentified mycobacteria. Genomic identification of this Tsukamurella species helped clarify its clinical characteristics and epidemiology. 相似文献
85.
86.
87.
Kazuyuki Hanajiri Hiroshi Mitsui Toshiyuki Maruyama Naoaki Hashimoto Masataka Sata Masao Omata 《Journal of gastroenterology and hepatology》2009,24(5):866-871
Background and Aim: There have so far been few reports describing echographic studies of chemically-induced carcinogenesis in rodent livers. Using echography, we observed diethylnitrosamine-induced liver tumors in rats and examined the effect of an intratumoral injection of an inhibitor of c-Jun N-terminal kinase.
Methods: Male Wistar rats were given 100 ppm of diethylnitrosamine for 6 weeks and their liver nodules were examined by echography weekly. The size of the nodules was measured and they were examined histologically. The effect of SP600125, an inhibitor of c-Jun N-terminal kinase, on the growth of rat hepatoma cell line McA-RH7777 was tested in vitro . Thereafter, SP600125 was injected into the liver nodules under echographic guidance in vivo and the changes in the proliferating cell nuclear antigen expression and size of the nodules were examined.
Results: The four distinct lobes of rat livers were clearly observed by transabdominal echography. The nodules in the livers were first detected 6 weeks after the treatment began, when they were as small as 1.6 mm in diameter. The nodules thereafter became more malignant histologically as they grew larger than 4 mm. SP600125 decreased the expression of proliferating cell nuclear antigen and the growth of McA-RH7777 cells. After SP600125 was injected in vivo , the proliferating cell nuclear antigen level and the growth rate of the rat liver nodules all significantly decreased.
Conclusions: Our results indicate that echography is quite useful for follow-up studies of liver carcinogenesis in rats, and c-Jun N-terminal kinase might be another therapeutic target in liver neoplasms. 相似文献
Methods: Male Wistar rats were given 100 ppm of diethylnitrosamine for 6 weeks and their liver nodules were examined by echography weekly. The size of the nodules was measured and they were examined histologically. The effect of SP600125, an inhibitor of c-Jun N-terminal kinase, on the growth of rat hepatoma cell line McA-RH7777 was tested in vitro . Thereafter, SP600125 was injected into the liver nodules under echographic guidance in vivo and the changes in the proliferating cell nuclear antigen expression and size of the nodules were examined.
Results: The four distinct lobes of rat livers were clearly observed by transabdominal echography. The nodules in the livers were first detected 6 weeks after the treatment began, when they were as small as 1.6 mm in diameter. The nodules thereafter became more malignant histologically as they grew larger than 4 mm. SP600125 decreased the expression of proliferating cell nuclear antigen and the growth of McA-RH7777 cells. After SP600125 was injected in vivo , the proliferating cell nuclear antigen level and the growth rate of the rat liver nodules all significantly decreased.
Conclusions: Our results indicate that echography is quite useful for follow-up studies of liver carcinogenesis in rats, and c-Jun N-terminal kinase might be another therapeutic target in liver neoplasms. 相似文献
88.
89.
90.
Tetsuro Okabe Michio Fujisawa Takasi Sekiya Yaeko Ichikawa Jun Goto 《Geriatrics & Gerontology International》2007,7(2):195-197
A case of familial spinocerebellar ataxia 6 with typical symptoms is presented. A 60-year-old Japanese female suffered from gait disturbance, ataxia and dizziness. Head magnetic resonance imaging revealed a typical atrophic image in cerebellum. Genetic tests revealed an expanded allele of 22 CAG repeats at the spinocerebellar ataxia type 6 locus. She was diagnosed with spinocerebellar ataxia 6. Her mother was also diagnosed with the same disease. A mixture of 18 medicinal herbs (modified Zhengan Xifeng Tang) was given according to the differential diagnosis based on the guidelines of traditional Chinese medicine. All of the symptoms were remarkably improved after 60 days of the herbal treatment. One year after discontinuation of the treatment, she complained of gait ataxia. She was treated with the modified Zhengan Xifeng Tang for 60 days. Gait ataxia was markedly improved by the second treatment. Fifteen months after discontinuation of the second treatment, she complained of gait ataxia again. The same remedy was given for 60 days. Gait ataxia was remarkably reduced again. The results may imply therapeutic potential of the medicinal herbs for spinocerebellar ataxia 6. 相似文献