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101.
102.
Nilüfer Aylin Acet
ztürk Asli G. Dilektasli
zge AydnGülü Ezgi Demirden Funda Cokun Ahmet Ursava Mehmet Karada Esra Uzaslan 《The clinical respiratory journal》2022,16(1):49
IntroductionEosinophilic airway inflammation is a recognized inflammatory pattern in subgroups of patients with chronic obstructive pulmonary disease (COPD). However, there are still conflicting results between various studies concerning the effect of eosinophils in COPD patients. Our aim with this study was to evaluate eosinophilic inflammation and its relation to the clinical characteristics in a group of COPD patients.MethodsStable COPD patients with FEV1% predicted < 50 or with ≥ 1 exacerbation leading to hospital admission or ≥2 moderate or severe exacerbation history were consecutively enrolled from outpatient clinics.ResultsWe included 90 male COPD patients, with a mean age of 63.3 ± 9.2. Mean FEV1% predicted was 35.9 ± 11.3. Eosinophilic inflammation (eosinophil percentage ≥2%) was evident in 54 (60%) of the patients. Participants with eosinophilic inflammation were significantly older and had better FEV1 predicted % values. Eosinophilic COPD patients were characterized with better quality of life and fewer symptoms. COPD patients with noneosinophilic inflammation used supplemental long‐term oxygen therapy (LTOT) more frequently compared to patients with eosinophilic inflammation (36.1% vs. 14.8%, p = 0.01). Eosinophilic inflammation is associated with less dyspnea severity measured by mMRC (OR: 0.542 95% CI: 0.342–0.859, p = 0.009) and less LTOT use (OR: 0.334 95% CI: 0.115–0.968, p = 0.04) regardless of age, severity of airflow limitation, and having frequent exacerbation phenotype.ConclusionOur study supports the growing evidence for a potential role of eosinophilic inflammation phenotype in COPD with distinctive clinical characteristics. Eosinophilic inflammation is inversely associated with dyspnea severity measured by mMRC and LTOT use independently from age, total number of exacerbations, St. George Respiratory Questionnaire (SGRQ) total score and FEV1% predicted. 相似文献
103.
目的 探讨血清胱抑素(Cyst-C)、尿微量白蛋白/肌酐(UmAlb/UCr)对高血压患者早期肾损害的诊断价值.方法 根据肾动态显像结果将85例原发性高血压患者分为早期肾功能损害组(A组)32例和单纯高血压组(B组)53例,并选取健康体检者50例为对照组,采用酶联免疫法测定各组Cyst-C、UmAlb/UCr、血清尿素氮(BUN)、血清肌酐(Scr)含量.结果 与对照组相比,A组及B组Cyst-C、UmAlb/UCr水平显著升高,B组则高于A组,差异有统计学意义(P<0.05),而三组BUN、Scr水平比较差异无统计学意义(P>0.05).随着高血压分级的增加,Cyst-C、UmAlb/UCr水平显著上升,其中Ⅲ级组患者显著高于Ⅰ级组及Ⅱ级组,差异有统计学意义(P.<0.05).Cyst-C灵敏性、特异性、准确性分别为81.6%、82.3%、69.2%,UmAlb/UCr灵敏性、特异性、准确性分别为84.5%、83.4%、76.9%,而UmAlb/UCr+Cyst-C灵敏性、特异性、准确性分别为93.2%、91.3%、92.3%.B组Cyst-C与UmAlb/UC联合检测阳性率显著高于单纯UmAlb/UCr或Cyst-C检测,差异有统计学意义(P<0.05).结论 Cyst-C与UmAlb/UC联合检测有助于高血压患者早期肾损害的诊断. 相似文献
104.
Chemical hair removal products are available as creams, gels, powders, aerosols and roll-ons and all of these forms work in the same way by breaking chemical bonds between sulfur atoms in the protein. Currently, the common active ingredients of these products are calcium thioglycolate, potassium thioglycolate, arsenic and sulfur minerals. Sulfur and arsenic containing products are important toxic chemicals which are mainly used for removing hair in developing countries. Irritant contact dermatitis accounts for 80% of all contact dermatitis reactions which are often occupation-related. Toluene sulfonamide, formaldehyde resin, acrylates and ethylcyanoacrylate are the most common irritants. Irritant nail dermatitis with plants has been well defined with Lobelia richardii flower, Compositae family and garlic. Although allergic dermatitis, irritant dermatitis and irritant nail dermatitis have been well demonstrated with chemicals, koilonychia is unusual presentation of irritant dermatitis. Here we describe a case of nail irritant dermatitis due to application of chemical depilatory product for hair removal presented with koilonychias. To our knowledge this is the first case of such presentation with koilonychia in the English literature. 相似文献
105.
Incremental value of live/real time three‐dimensional transesophageal echocardiography over the two‐dimensional technique in the assessment of a tuberculoma involving the left atrium and appendage 下载免费PDF全文
Tuğba Kemaloğlu Öz M.D. Mahmoud Elsayed M.B.B.Ch Navin C. Nanda M.D. Koray Kalenderoğlu M.D. Şükrü Akyüz M.D. Işıl Atasoy M.D. Altuğ Ösken M.D. Tolga Onuk M.D. Mehmet Eren M.D. 《Echocardiography (Mount Kisco, N.Y.)》2016,33(9):1409-1412
Intracardiac tuberculomas are extremely rare, and cardiac involvement in tuberculosis accounts for only 0.5% of extrapulmonary tuberculosis. We report for the first time incremental value of live/real time three‐dimensional transesophageal echocardiography over two‐dimensional transesophageal echocardiography in the assessment of a tuberculoma involving the left atrium and left atrial appendage. 相似文献
106.
Mehmet Erturk Hamdi Pusuroglu Ali Kemal Kalkan Muhammet Gurdogan Ibrahim Faruk Akturk 《Clinical and experimental hypertension (New York, N.Y. : 1993)》2014,36(8):572-578
Objectives: To evaluate subclinical left ventricular and right ventricular systolic impairment in dipper and non-dipper hypertensives by using isovolumic acceleration.Methods: About 45 normotensive healthy volunteers (20 men, mean age 43?±?9 years), 45 dipper (27 men, mean age 45?±?9 years) and 45 non-dipper (25 men, 47?±?7 years) hypertensives were enrolled. Isovolumic acceleration was measured by dividing the peak myocardial isovolumic contraction velocity by isovolumic acceleration time.Results: Non-dippers indicated lower left ventricular (2.2?±?0.4?m/s2 versus 2.8?±?1.0?m/s2, p?0.01) and right ventricular isovolumic acceleration values (2.8?±?0.8?m/s2 versus 3.5?±?1.0?m/s2, p?=?0.012) compared with dippers. Left ventricular mass index (p?=?0.001), interventricular septal thickness (p?=?0.002) and myocardial performance index (p?0.001) were negatively correlated with left ventricular isovolumic acceleration. Left ventricular septal thickness (p?=?0.002), mass index (p?=?0.001) and right ventricular myocardial performance index (p?0.001) were negatively correlated with right ventricular isovolumic acceleration.Conclusion: The present study demonstrates that non-dipper hypertensives have increased left and right ventricular subclinical systolic dysfunction compared with dippers. Isovolumic acceleration is the only echocardiographic parameter in predicting this subtle impairment. 相似文献
107.
108.
Cetin Gecmen MD Gonca G. Gecmen MD Muzaffer Kahyaoglu MD Mehmet Aksut MD Nuri Havan MD Ahmet Guner MD Ender O. Cakmak MD Sukran Sarikaya MD Semih Kalkan MD Murat Rabus MD 《Echocardiography (Mount Kisco, N.Y.)》2017,34(8):1234-1235
An 83‐year‐old male patient presented to the outpatient clinic with complaint of swelling at right antecubital area. Ultrasonographic examination of the right upper extremity revealed a mass lesion within the right cephalic vein, which was consistent with thrombus. A computed tomography (CT) venography showed contrast enhancement in cephalic vein at distal arm and an aneurysmatic thrombus area displaying regular borders with a size of 28*30 mm; there was no contrast enhancement at more proximal levels at the cephalic vein. 相似文献
109.
110.