全文获取类型
收费全文 | 1829篇 |
免费 | 138篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 57篇 |
妇产科学 | 24篇 |
基础医学 | 218篇 |
口腔科学 | 63篇 |
临床医学 | 225篇 |
内科学 | 383篇 |
皮肤病学 | 29篇 |
神经病学 | 123篇 |
特种医学 | 214篇 |
外科学 | 176篇 |
综合类 | 104篇 |
预防医学 | 116篇 |
眼科学 | 21篇 |
药学 | 91篇 |
1篇 | |
中国医学 | 2篇 |
肿瘤学 | 119篇 |
出版年
2023年 | 7篇 |
2022年 | 20篇 |
2021年 | 26篇 |
2020年 | 10篇 |
2019年 | 14篇 |
2018年 | 29篇 |
2017年 | 20篇 |
2016年 | 23篇 |
2015年 | 28篇 |
2014年 | 53篇 |
2013年 | 68篇 |
2012年 | 80篇 |
2011年 | 75篇 |
2010年 | 58篇 |
2009年 | 71篇 |
2008年 | 70篇 |
2007年 | 84篇 |
2006年 | 93篇 |
2005年 | 59篇 |
2004年 | 54篇 |
2003年 | 68篇 |
2002年 | 50篇 |
2001年 | 58篇 |
2000年 | 58篇 |
1999年 | 49篇 |
1998年 | 39篇 |
1997年 | 65篇 |
1996年 | 60篇 |
1995年 | 45篇 |
1994年 | 51篇 |
1993年 | 50篇 |
1992年 | 39篇 |
1991年 | 28篇 |
1990年 | 33篇 |
1989年 | 34篇 |
1988年 | 39篇 |
1987年 | 28篇 |
1986年 | 23篇 |
1985年 | 19篇 |
1984年 | 19篇 |
1983年 | 18篇 |
1982年 | 20篇 |
1981年 | 15篇 |
1980年 | 11篇 |
1979年 | 13篇 |
1978年 | 8篇 |
1977年 | 10篇 |
1976年 | 18篇 |
1975年 | 11篇 |
1967年 | 6篇 |
排序方式: 共有1974条查询结果,搜索用时 15 毫秒
91.
Prevalence of Candida spp., xerostomia,and hyposalivation in oral lichen planus – A controlled study
Objective
To determine the frequency of Candida spp., xerostomia, and salivary flow rate (SFR) in three different groups: patients with OLP (OLP group), patients with oral mucosal lesions other than OLP (non‐OLP group), and subjects without oral mucosal lesions (control group).Material and methods
Xerostomia as well as SFR was investigated in the three groups. Samples for isolation of Candida spp. were collected from OLP lesions (38 patients), non‐OLP lesions (28 patients), and healthy subjects (32 subjects).Results
There was no statistically significant difference regarding the frequency of xerostomia and hyposalivation among the three groups (P > 0.05). A higher prevalence for colonization by Candida spp. was found in the healthy subject as compared to that of patients with OLP (P = 0.03) and non‐OLP (P = 0.02) groups. Low SFR was not a factor for colonization by Candida spp.Conclusions
Xerostomia and hyposalivation occur with similar frequency in subjects with and without oral lesions; also, the presence of oral lesions does not increase the susceptibility to colonization by Candida spp. It seems that any study implicating Candida spp. in the malignant transformation of oral lesions should be carried out mostly on a biochemical basis, that is, by testing the capability of Candida spp. to produce carcinogenic enzyme. 相似文献92.
KH Neppelenbroek RS Seó VM Urban S Silva LN Dovigo JH Jorge NH Campanha 《Oral diseases》2014,20(4):329-344
In healthy individuals, Candida species are considered commensal yeasts of the oral cavity. However, these microorganisms can also act as opportunist pathogens, particularly the so‐called non‐albicans Candida species that are increasingly recognized as important agents of human infection. Several surveys have documented increased rates of C. glabrata, C. tropicalis, C. guilliermondii, C. dubliniensis, C. parapsilosis, and C. krusei in local and systemic fungal infections. Some of these species are resistant to antifungal agents. Consequently, rapid and correct identification of species can play an important role in the management of candidiasis. Conventional methods for identification of Candida species are based on morphological and physiological attributes. However, accurate identification of all isolates from clinical samples is often complex and time‐consuming. Hence, several manual and automated rapid commercial systems for identifying these organisms have been developed, some of which may have significant sensitivity issues. To overcome these limitations, newer molecular typing techniques have been developed that allow accurate and rapid identification of Candida species. This study reviewed the current state of identification methods for yeasts, particularly Candida species. 相似文献
93.
94.
95.
Fiona Ashford Angus Best Steven J. Dunn Zahra Ahmed Henna Siddiqui Jordan Melville Samuel Wilkinson Jeremy Mirza Nicola Cumley Joanne Stockton Jack Ferguson Lucy Wheatley Elizabeth Ratcliffe Anna Casey Tim Plant The COVID- Genomics UK Consortium Joshua Quick Alex Richter Nicholas Loman Alan McNally 《Journal of clinical microbiology》2022,60(4)
96.
Anxiety sensitivity in agoraphobics 总被引:1,自引:0,他引:1
This study further validated the "Reiss-Epstein-Gursky Anxiety Sensitivity Index" (ASI) as a measure of the fear of anxiety. Agoraphobics scored high on the ASI before, but not after, behavioral treatment. Residual anxiety sensitivity, however, did not predict resurgence of agoraphobic avoidance at six months follow-up. Indeed, anxiety sensitivity continued to decline during the follow-up period. Multiple regression analyses indicated that the ASI predicted the number of fears in agoraphobics beyond that predicted by the level of general anxiety. This finding supports the hypothesis that high anxiety sensitivity enhances fear acquisition; it also suggests that the ASI measures a construct different from that measured by general anxiety scales. Empirical similarities and differences were found between the ASI and two other "fear of fear" measures: the Agoraphobic Cognitions Questionnaire and the Body Sensations Questionnaire. 相似文献
97.
Marcus Eng Hock Ong MBBS MPH Tom P. Aufderheide MD MS Graham Nichol MD MPH FRCP Bentley J. Bobrow MD Leo Bossaert MD Peter Cameron MBBS MD Judith Finn PhD RN RM ICCert FRCNA Ian Jacobs PhD FRCNA Rudolph W. Koster MD PhD Bryan McNally MD MPH Yih Yng Ng MBBS MPH MBA Sang Do Shin MD MPH PhD George Sopko MD MPH Hideharu Tanaka MD PhD Taku Iwami MD PhD Mark Hauswald MD 《Academic emergency medicine》2013,20(12):1297-1303
At the 2013 Academic Emergency Medicine global health consensus conference, a breakout session to develop a research agenda for resuscitation was held. Two articles are the result of that discussion. This second article addresses data collection, management, and analysis and regionalization of postresuscitation care, resuscitation programs, and research examples around the world and proposes a strategy to strengthen resuscitation research globally. There is a need for reliable global statistics on resuscitation, international standardization of data, and development of an electronic standard for reporting data. Regionalization of postresuscitation care is a priority area for future research. Large resuscitation clinical research networks are feasible and can give valuable data for improvement of service and outcomes. Low‐cost models of population‐based research, and emphasis on interventional and implementation studies that assess the clinical effects of programs and interventions, are needed to determine the most cost‐effective strategies to improve outcomes. The global challenge is how to adapt research findings to a developing world situation to have an effect internationally. 相似文献
98.
Ashling McNally Jan Ibbetson Shireen Sidhu 《The Australasian journal of dermatology》2017,58(1):53-57
We present three patients with azathioprine‐induced Sweet's syndrome (AISS) who attended our tertiary institution within a 12‐month period. Established associations exist between Sweet's syndrome and some medications; however, to date links to azathioprine are tentative. While there are case reports of AISS, most have occurred in patients with inflammatory bowel disease (IBD), an underlying predisposition for Sweet's syndrome. Our case series adds to the evidence that the entity of AISS truly exists independent of confounding factors such as concurrent IBD. 相似文献
99.
Clinical studies show an association between changed load patterns both in the disc and its adjacent vertebral body, with painful degenerated discs. This suggests that failure to restore the normal loading pattern on implantation of a disc replacement could be a cause of lower clinical success rate. In the present study the variations of load patterns in the vertebra after disc implantation was studied using a simplified finite element models of natural and artificial discs. The effect of implant size and presence of voids at the implant–bony endplate interface were studied, for the worst case scenario of no bone remodelling. An altered stress pattern was observed in the vertebrae of implanted segments. The use of smaller size implants and presence of voids at the interface caused localized stress concentration in the endplate and adjacent cancellous bone. The study results support the hypothesis that current implants fail to restore normal loading patterns in the vertebral body, and the localized high stress regions could be the source of pain, and the cause of low success rate of TDRs. 相似文献
100.