全文获取类型
收费全文 | 9428篇 |
免费 | 1031篇 |
国内免费 | 29篇 |
专业分类
耳鼻咽喉 | 80篇 |
儿科学 | 344篇 |
妇产科学 | 194篇 |
基础医学 | 1266篇 |
口腔科学 | 301篇 |
临床医学 | 1019篇 |
内科学 | 1773篇 |
皮肤病学 | 117篇 |
神经病学 | 903篇 |
特种医学 | 385篇 |
外科学 | 1275篇 |
综合类 | 451篇 |
一般理论 | 7篇 |
预防医学 | 1023篇 |
眼科学 | 273篇 |
药学 | 569篇 |
中国医学 | 41篇 |
肿瘤学 | 467篇 |
出版年
2022年 | 65篇 |
2021年 | 153篇 |
2020年 | 123篇 |
2019年 | 161篇 |
2018年 | 171篇 |
2017年 | 144篇 |
2016年 | 128篇 |
2015年 | 159篇 |
2014年 | 222篇 |
2013年 | 357篇 |
2012年 | 430篇 |
2011年 | 459篇 |
2010年 | 288篇 |
2009年 | 270篇 |
2008年 | 385篇 |
2007年 | 401篇 |
2006年 | 416篇 |
2005年 | 390篇 |
2004年 | 365篇 |
2003年 | 296篇 |
2002年 | 316篇 |
2001年 | 291篇 |
2000年 | 281篇 |
1999年 | 270篇 |
1998年 | 135篇 |
1997年 | 145篇 |
1996年 | 138篇 |
1995年 | 113篇 |
1994年 | 106篇 |
1993年 | 102篇 |
1992年 | 214篇 |
1991年 | 186篇 |
1990年 | 214篇 |
1989年 | 223篇 |
1988年 | 208篇 |
1987年 | 164篇 |
1986年 | 166篇 |
1985年 | 169篇 |
1984年 | 122篇 |
1983年 | 110篇 |
1982年 | 84篇 |
1981年 | 68篇 |
1979年 | 118篇 |
1978年 | 97篇 |
1977年 | 84篇 |
1976年 | 71篇 |
1974年 | 71篇 |
1973年 | 95篇 |
1972年 | 87篇 |
1971年 | 75篇 |
排序方式: 共有10000条查询结果,搜索用时 296 毫秒
41.
Septic discitis refers to a primary suppurative process involving the intervertebral disc space and occurs as a result of hematogenous invasion or contamination by pyogenic organisms. A case of septic discitis is described in a 77-year-old woman following an episode of Escherichia coli urosepsis. Despite bed rest, an orthosis, and appropriate antibiotics, the patient ultimately had to undergo surgical disc removal. The diagnosis of septic discitis is often made in the context of other diseases that share common clinical and laboratory findings. Magnetic resonance imaging appears well suited for diagnostic confirmation of septic discitis. Needle biopsy and aspiration results should be used to determine the appropriate choice of antibiotic for this disease process. 相似文献
42.
Serum ionic fluoride levels in haemodialysis and continuous ambulatory peritoneal dialysis patients 总被引:1,自引:1,他引:0
al-Wakeel JS; Mitwalli AH; Huraib S; al-Mohaya S; Abu-Aisha H; Chaudhary AR; al-Majed SA; Memon N 《Nephrology, dialysis, transplantation》1997,12(7):1420-1424
High serum fluoride (F-) in patients with chronic renal failure (CRF) and
end-stage renal disease (ESRD) is associated with risk of renal
osteodystrophy and other bone changes. This study was done to determine F-
in normal healthy controls and patients with ESRD on haemodialysis (HD) or
peritoneal dialysis (PD). Seventeen healthy controls (12 males, 5 females)
and 39 ESRD patients on dialysis (17 males, 22 females) were recruited in
the study in a community with 47.4 +/- 3.28 microM/l (range 44-51 microM/l)
of F- content in drinking water. Control subjects showed a mean serum F-
concentration of 1.08 +/- 0.350 microM/l. Males in control group showed
slightly higher F- levels (1.15 +/- 0.334, range 0.55-1.9 microM/l) than
females (0.92 +/- 0.370, range 0.6-1.5 microM/l). Mean serum F-
concentration did not correlate significantly with age and sex among
control subjects, whereas such correlation was observed in patients with
ESRD on dialysis. Mean serum F- concentration was significantly higher in
patients on dialysis (2.67 +/- 1.09, range 0.8-5.2 microM/l) than normal
controls. When grouped according to sex, the mean serum F- concentration in
males (3.05 +/- 1.04, range 1.8-5.2 microM/l) was significantly higher than
females (2.38 +/- 1.08, range 0.8-5.2 microM/l). When patients were grouped
according to age, it was observed that F- concentration was significantly
higher in patients with age groups 21-70 (2.86 +/- 1.05) than those with
age group 13-20 years (1.42 +/- 0.531). Thus F- concentration correlated
with age and sex, being higher in males and above 20 years. Despite
appreciable clearance of F- (39-90%) across the peritoneum, patients on
CAPD showed higher serum F- concentration than those on HD (3.1 +/- 1.97 vs
2.5 +/- 1.137 microM/l). Of the total 39 patients on dialysis 39% had their
serum F- concentration above 3.0 microM/l, posing the risk of renal
osteodystrophy.
相似文献
43.
Experience with the endorectal ileal pullthrough with lateral reservoir for ulcerative colitis and polyposis 总被引:3,自引:0,他引:3
E W Fonkalsrud M Stelzner N McDonald 《Archives of surgery (Chicago, Ill. : 1960)》1988,123(9):1053-1058
Since 1977, 184 patients with colitis or polyposis underwent colectomy with endorectal ileal pullthrough in two stages with a temporary ileostomy. Five had an S reservoir, three had a J reservoir, and 15 had no reservoir; 97 patients had a lateral reservoir constructed at the second operation and 64 had one constructed at the first operation. Ten patients with no reservoir and one with a J reservoir underwent conversion to a lateral reservoir because of stool frequency. Three patients with an S reservoir and six (3.5%) of 172 patients with a lateral reservoir underwent a permanent ileostomy. Over 65% of complications occurred in the first 50 patients. Late reservoir shortening was necessary in 34 patients. Of the last 110 patients, 107 are functioning well with a mean of six bowel movements per day. A short lateral reservoir (less than 15 cm) constructed at the first operation produces the fewest complications and best results. 相似文献
44.
QuickVue Influenza Test for Rapid Detection of Influenza A and B Viruses in a Pediatric Population 下载免费PDF全文
Caroline Quach Diane Newby Ghislaine Daoust Earl Rubin Jane McDonald 《Clinical and Vaccine Immunology : CVI》2002,9(4):925-926
The performance of a lateral-flow immunoassay, the QuickVue Influenza Test, for detection of influenza A and B viruses in comparison with that of cell culture was evaluated by using nasopharyngeal aspirates, in viral transport medium, from children with respiratory tract infections. The sensitivity and specificity were 79.2 and 82.6%, respectively. 相似文献
45.
46.
47.
48.
Macran S. Kind P. Collingwood J. Hull R. McDonald I. Parkinson L. 《Quality of life research》2003,12(2):177-188
This study reports on the preliminary testing of a new measure designed for use alongside EQ-5D in evaluating outcomes in podiatry: the Podiatry Health Questionnaire (PHQ). Individuals aged 18 years or more, receiving podiatry services in clinic or domicilliary locations across four NHS Trusts in Yorkshire and Humberside UK took part in a questionnaire survey. Respondents reported high levels of problems on all six PHQ dimensions. Correlations suggested that the PHQ and EQ-5D were measuring distinct constructs. The levels on each dimension were well defined in terms of self-rated morbidity on the PHQ visual analogue scale (PHQvas) and the EQ-5Dvas, although PHQvas appeared to be slightly more sensitive to changes in health on the dimensions. There was a strong relationship between clinicians' Podiatry Clinical Score rating and reported symptoms for four out of six PHQ dimensions and PHQvas. The PHQ was able to distinguish respondents in terms of their self-reported morbidity in EQ-5D and in terms of their morbidity as assessed by clinicians. It is suggested that the respondent completed PHQ appears to be a useful new measure for assessing foot-related health. However, further investigation of the psychometric properties of the measure is required. 相似文献
49.
OBJECTIVE: Clinical reports over the last 60 years suggest that the amobarbital interview is effective in relieving catatonic symptoms. This has never been substantiated with methodologically sound trials. The authors postulated that a randomized blind comparison of intravenous amobarbital and saline would demonstrate the superiority of amobarbital in relieving catatonic mutism. METHOD: The subjects were 20 inpatients with catatonic mutism. They were randomly assigned to either saline (N = 10) or a 5% amobarbital solution (N = 10), and the infusions were administered intravenously at a rate of 1 cc/min or less over 10 minutes by a blinded physician. A second blinded physician administered a semistructured interview during the infusion to control for the effect of suggestion. A third blinded physician rated patient responsiveness, reactivity, and arousal. Any patient who was unresponsive to the initial infusion was crossed over to the other infusion. Interviews were videotaped for determination of interrater reliability. RESULTS: In the initial infusions, six of 10 patients responded to amobarbital and zero of 10 responded to saline. Four of the saline nonresponders responded when given amobarbital. Response was evident by the 4th minute of the amobarbital infusion. Interrater reliability was high. The responders and nonresponders differed significantly in the variance of the weight-adjusted amobarbital dose, and the responders tended to be older and female. CONCLUSIONS: Intravenous amobarbital is superior to saline in relieving catatonic mutism, although only 50% of these patients responded. The nonresponders were distinguished from the responders by a greater variance in the weight-adjusted dose of amobarbital. 相似文献
50.
Effect of 30 per cent maternal nutrient restriction from 0.16 to 0.5 gestation on fetal baboon kidney gene expression 总被引:4,自引:1,他引:3