全文获取类型
收费全文 | 5080篇 |
免费 | 374篇 |
国内免费 | 30篇 |
专业分类
耳鼻咽喉 | 38篇 |
儿科学 | 163篇 |
妇产科学 | 180篇 |
基础医学 | 594篇 |
口腔科学 | 238篇 |
临床医学 | 527篇 |
内科学 | 917篇 |
皮肤病学 | 225篇 |
神经病学 | 345篇 |
特种医学 | 500篇 |
外科学 | 446篇 |
综合类 | 77篇 |
一般理论 | 7篇 |
预防医学 | 382篇 |
眼科学 | 92篇 |
药学 | 345篇 |
中国医学 | 49篇 |
肿瘤学 | 359篇 |
出版年
2024年 | 9篇 |
2023年 | 105篇 |
2022年 | 202篇 |
2021年 | 329篇 |
2020年 | 220篇 |
2019年 | 332篇 |
2018年 | 351篇 |
2017年 | 224篇 |
2016年 | 224篇 |
2015年 | 234篇 |
2014年 | 299篇 |
2013年 | 320篇 |
2012年 | 452篇 |
2011年 | 424篇 |
2010年 | 191篇 |
2009年 | 154篇 |
2008年 | 224篇 |
2007年 | 217篇 |
2006年 | 166篇 |
2005年 | 129篇 |
2004年 | 124篇 |
2003年 | 92篇 |
2002年 | 98篇 |
2001年 | 49篇 |
2000年 | 33篇 |
1999年 | 30篇 |
1998年 | 7篇 |
1997年 | 8篇 |
1996年 | 6篇 |
1995年 | 4篇 |
1993年 | 9篇 |
1992年 | 16篇 |
1991年 | 27篇 |
1990年 | 14篇 |
1989年 | 22篇 |
1988年 | 12篇 |
1987年 | 22篇 |
1986年 | 11篇 |
1985年 | 20篇 |
1984年 | 9篇 |
1983年 | 8篇 |
1982年 | 6篇 |
1981年 | 4篇 |
1980年 | 4篇 |
1978年 | 3篇 |
1977年 | 6篇 |
1976年 | 6篇 |
1971年 | 5篇 |
1970年 | 5篇 |
1969年 | 4篇 |
排序方式: 共有5484条查询结果,搜索用时 15 毫秒
31.
32.
Geir Bjørklund Nagwa A. Meguid Afaf El-Ansary Mona A. El-Bana Maryam Dadar Jan Aaseth Maha Hemimi Joško Osredkar Salvatore Chirumbolo 《Journal of molecular neuroscience : MN》2018,66(4):492-511
Autism spectrum disorder (ASD) is a neurodevelopmental disorder afflicting about one in every 68 children. It is behaviorally diagnosed based on a triad of symptoms, including impairment in communication, impairment in sociability and abnormal and stereotypic behavior. The subjectivity of behavioral diagnosis urges the need for clinical biomarker tests to improve and complement ASD diagnosis and treatment. Over the past two decades, researchers garnered a broad range of biomarkers associated with ASD and often correlating with the severity of ASD, which includes metabolic and genetic biomarkers or neuroimaging abnormalities. Metabolic biomarkers are either involved in key pathways such as a trans-sulfuration pathway or produced due to the derangement of these pathways in the case of oxidative stress. Recent studies reported several genetic abnormalities related to ASD, encompassing various mechanisms, from copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) to chromosomal anomalies. However, it is still premature to consider these genetic variants as true biomarkers for ASD, due to their low reproducibility and regional-specific nature. Herein, we comprehensively review state of the art about major biomarkers reported in ASD and the association of some biomarkers with ASD symptoms and severity. It is important to establish those biomarkers to be able to help in the diagnosis and to optimize the treatment of ASD. 相似文献
33.
The Interactive Whiteboard (IWB) is now a common technological artefact in Swedish preschools and schools. This study examines preschool teachers’ thinking behind the embedding of IWB in the early years’ mathematics classroom and how preschool teachers structure their mathematical activities when using IWB. Two complementary empirical studies, that is, interviews and video observations, were conducted with four preschool teachers. The findings demonstrate that (just) having a positive attitude to technological artefacts like IWB is less likely to enrich the learning environment and lead to pedagogical change. This suggests that teachers’ IWB use is mostly informed by their pedagogical knowledge. 相似文献
34.
35.
Maryam Esmaeili Martin Berry Ann Logan Zubair Ahmed 《中国神经再生研究》2014,9(18):1653-1656
The scarring response after a penetrant central nervous system injury results from the interaction between invading leptominingeal/pericyte-derived fibroblasts and endogenous reactive astrocytes about the wound margin. Extracellular matrix and scar-derived axon growth inhibitory mole- cules fill the lesion site providing both a physical and chemical barrier to regenerating axons. Dec orin, a small leucine-rich chondroitin-dermatan sulphate proteoglycan expressed by neurons and astrocytes in the central nervous system, is both anti-fibrotic and anti-inflammatory and attenu- ates the formation and partial dissolution of established and chronic scars. Here, we discuss the potential of using Decorin to antagonise scarring in the central nervous system. 相似文献
36.
37.
Maryam Farzad Fereydoun Layeghi Ali Asgari Seyed Ali Hosseini Mehdi Rassafiani 《Journal of hand and microsurgery》2014,6(1):27-34
The objective of the study is to provide information about non disease specified outcome measures which evaluate disability in patients who have impairments in hand and upper extremity and to find the extent to which they are evaluating “disability” based on ICF hand Core Set (activity limitation and participation restriction). MEDLINE, CINAHL, GOOGLE SCHOLAR , OVID and SCIENCE DIRECT databases were systematically searched for studies on non disease specified outcome measures used to evaluate upper extremity function; only studies written in English were considered. We reviewed titles and abstracts of the identified studies to determine whether the studies met predefined eligibility criteria (eg, non disease specified out come measures used in hand injured patients). All the outcome measures which had eligibility included. After full text review ,7 non disease specified outcome measures in hand were identified. Studies were extracted, and the information retrieved from them. All the outcome measures which had incuded, were linked with ICF hand core set disability part (activity and participation). All of them only linked to 16 (42 %) components of ICF hand Core Set, which were most activity and less participation from ICF. None of the non disease specified out come measures in hand injuries cover all domains of disability from the ICF Hand Core Set. 相似文献
38.
Hamidreza Pouraliakbar Maryam Pourmojib Yousef Rezaei Saeid Hosseini 《Journal of the Saudi Heart Association》2018,30(4):328-330
Pericardial patch has been used to repair cardiac defects; however, its strength as an aortoplasty patch to tolerate systemic pressure is a matter of debate. We report an aneurysmal dilatation of pericardial patch in aortoplasty. Our patient was a 56-year-old female known case of rheumatic heart disease that underwent redoes mitral and aortic valve replacements along with Manouguian aortoplasty at the age of 44?years old. After 2?months, she was readmitted with a diagnosis of endocarditis. Echocardiography revealed a small cavity in the posterior wall of the aorta. She responded to medical therapy and discharged in a good condition. Twelve years later, she was scheduled to undergo reoperation due to a severe paraprosthetic aortic valve leakage and a pericardial patch aneurysm. The leaking prosthetic aortic valve was explanted and the aneurysmal tissue was replaced with a polyethylene terephthalate patch. 相似文献
39.
Congenital aortocaval fistula between right aortic sinus of Valsalva and superior vena cava: A rare case report 下载免费PDF全文
Mozhdeh Dabirian MD Ali Ghaemian MD Maryam Nabati MD Samad Golshani MD Mojtaba Shokri MD 《Echocardiography (Mount Kisco, N.Y.)》2018,35(3):413-416
Thoracic aortocaval fistula is a very rare cause of left to right shunt. Drainage of fistula into the superior vena cava (SVC) is very uncommon. Clinical symptoms depend on the size of the shunt. We report a rare case of an asymptomatic 27‐year‐old woman with congenital aortocaval fistula to the SVC with a small amount of left to right shunt that was considered for serial medical follow‐up. 相似文献
40.
Mohamed Abd El-Aziz M. Farag Latifa Ahmad Alkandary Maryam Ibrahim Alshatti Maged Ali H. Shoukeer 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(3):873-877
Reported cases encountered difficulty in differentiating between inflammatory carcinoma and breast edema caused by congestive heart failure especially if the breast edema is unilateral. Our presented case is an elderly woman with unilateral breast edema due to congestive heart failure that was initially suspected to have breast cancer based on clinical findings. However imaging studies showed breast edema pattern with no definite underlying mass. This edema was resolved with standard treatment of heart failure. Congestive heart failure may be a possible cause of unilateral breast edema especially in a patient with background of congestive heart failure. 相似文献