全文获取类型
收费全文 | 119632篇 |
免费 | 6827篇 |
国内免费 | 731篇 |
专业分类
耳鼻咽喉 | 1153篇 |
儿科学 | 3901篇 |
妇产科学 | 2765篇 |
基础医学 | 17235篇 |
口腔科学 | 4139篇 |
临床医学 | 10822篇 |
内科学 | 27115篇 |
皮肤病学 | 3113篇 |
神经病学 | 11780篇 |
特种医学 | 2750篇 |
外国民族医学 | 1篇 |
外科学 | 10643篇 |
综合类 | 433篇 |
一般理论 | 55篇 |
预防医学 | 11766篇 |
眼科学 | 1967篇 |
药学 | 8461篇 |
中国医学 | 451篇 |
肿瘤学 | 8640篇 |
出版年
2024年 | 142篇 |
2023年 | 1191篇 |
2022年 | 2644篇 |
2021年 | 4388篇 |
2020年 | 2631篇 |
2019年 | 3600篇 |
2018年 | 4088篇 |
2017年 | 3023篇 |
2016年 | 3507篇 |
2015年 | 3895篇 |
2014年 | 5089篇 |
2013年 | 6683篇 |
2012年 | 10037篇 |
2011年 | 10364篇 |
2010年 | 5720篇 |
2009年 | 4782篇 |
2008年 | 8150篇 |
2007年 | 8136篇 |
2006年 | 7450篇 |
2005年 | 6943篇 |
2004年 | 6193篇 |
2003年 | 5503篇 |
2002年 | 4957篇 |
2001年 | 593篇 |
2000年 | 407篇 |
1999年 | 645篇 |
1998年 | 866篇 |
1997年 | 711篇 |
1996年 | 583篇 |
1995年 | 477篇 |
1994年 | 456篇 |
1993年 | 370篇 |
1992年 | 303篇 |
1991年 | 200篇 |
1990年 | 207篇 |
1989年 | 181篇 |
1988年 | 177篇 |
1987年 | 148篇 |
1986年 | 166篇 |
1985年 | 117篇 |
1984年 | 138篇 |
1983年 | 141篇 |
1982年 | 163篇 |
1981年 | 120篇 |
1980年 | 131篇 |
1979年 | 76篇 |
1978年 | 79篇 |
1977年 | 79篇 |
1976年 | 62篇 |
1974年 | 62篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
32.
Lucio Lucchin Amleto D’Amicis Maria Gabriella Gentile Nino Carlo Battistini Maria Antonia Fusco Augusta Palmo Maurizio Muscaritoli Franco Contaldo Emanuele Cereda 《Mediterranean journal of nutrition and metabolism》2009,2(3):171-179
Aim and methods Nutrition, unhealthy lifestyles and cancer appear to be strictly related, but few authors have analysed the interest in dietary
information of cancer patients and their families. This survey was conducted in the Veneto area (Italy) to investigate the
concern of cancer patients and their family members about diet as a health tool before and after diagnosis of cancer.
Results Seven hundred and four questionnaires were collected: 380 from cancer patients and 324 from family members of cancer subjects.
Breast cancer (BC) was the most frequent disease for patients (61.8%) as well as families (26.5%). Generally, the importance
of having precise diet information after diagnosis is recognised by 40.3% of patients, with significant differences between
the various types of cancer: gastric and colon/rectum cancer (GCC) patients were more concerned than BC women about precise
information concerning a diet to follow immediately after diagnosis (p = 0.000, ODs = 3.10, CI 1.68–5.71) or during treatments (p = 0.001, ODs = 2.67, CI 1.46–4.89). The nutritional information is supplied to patients in 34% of cases and to relatives
in 30.3%, often from non-medical sources. In total healthcare workers (family doctor, oncologist, surgeon, dietician) represented
the exclusive source of dietary information for 24.9% of patients and 22.9% of family members. Diet after diagnosis changes
in 69.1% of GCC patients and in 39.2% of BC women. Relatives, particularly women, report difficulties preparing patients’
meals in 30.7% of cases, changes in the eating habits of the entire family in 29.9% and discontent connected with patients
diet in 13.9%. The concern about proper nutrition after diagnosis increases more in GCC subjects (p < 0.025) when compared to BC subjects and in patients with more recent diagnosis (p < 0.041) when compared with patients with diagnosis >5 years ago, while in family members the interest in diet after diagnosis
increases more in women than in men (p < 0.030) without other differences regarding the degree of relationship, type of cancer or diagnosis time. Relatives (92.7%)
have more interest in nutritional education than patients (74.9%). Cancer patients <65 years were more interested in educational
initiatives concerning nutrition (p = 0.000, ODs = 4.46, CI 2.6–7.4) than older patients (>65 years) and female subjects were more concerned than male patients
(p = 0.008, ODs = 2.11, CI 1.2–3.6).
Conclusions The interest in the dietary knowledge and in educational initiatives concerning nutrition is high in cancer patients and their
relatives, although it decreases with the age. The poor attention paid to nutrition of cancer patients by various healthcare
workers deserves consideration, since the psychophysical wellbeing and perhaps also survival of cancer patients can be improved
by correct dietary management, as well as, naturally, by the principal treatments themselves. 相似文献
33.
Marta Méndez-López Magdalena Méndez Fernando Sánchez-Patán Isabel Casado Maria-Angeles Aller Laudino López Maria-Teresa Corcuera Maria-Jose Alonso Maria-Paz Nava Jaime Arias Jorge-Luis Arias 《Journal of gastrointestinal surgery》2007,11(2):187-194
To obtain a new model of chronic portal hypertension in the rat, two classical methods to produce portal hypertension, partial portal vein ligation and the oral administration of thioacetamide (TAA), have been combined. Male Wistar rats were divided into four groups: 1 (control; n?=?10), 2 [triple partial portal vein ligation (TPVL); n?=?9], 3 (TAA; n?=?11), and 4 (TPVL plus TAA; n?=?9). After 3 months, portal pressure, types of portosystemic collateral circulation, laboratory hepatic function tests (aspartate aminotransferase, alanine aminotransferase, bilirubin, alkaline phosphatase, and gamma-glutamyl transpeptidase) and liver histology were studied. The animals belonging to group 2 (TPVL) developed extrahepatic portosystemic collateral circulation, associated with mesenteric venous vasculopathy without hepatic destructurization or portal hypertension. Animals from group 3 (TAA) developed cirrhosis and portal hypertension but not extrahepatic portosystemic collateral circulation, or mesenteric venous vasculopathy. Finally, the animals from group 4 (TPVL?+?TAA) developed cirrhosis, portal hypertension, portosystemic collateral circulation, and mesenteric venous vasculopathy. The association of TPVL and TAA can be used to obtain a model of chronic portal hypertension in the rat that includes all the alterations that patients with hepatic cirrhosis usually have. This could, therefore, prove to be a useful tool to study the pathophysiological mechanisms involved in these alterations. 相似文献
34.
35.
Henyse G V Silva Rosangela P Tórtora Maria Lucia F Farias 《Gynecological endocrinology》2005,21(3):174-179
To evaluate the impact of pregnancy on bone, we studied bone turnover at the first (T1) and third (T3) trimester of gestation in 58 adolescents and 28 healthy adolescents who had never been pregnant. Total body (TB) and lumbar spine (LS) bone mineral density (BMD) and body composition were evaluated by dual-energy X-ray absorptiometry in all control patients (C) and after parturition in 28 pregnant patients (G). Paired and unpaired t tests, Mann-Whitney and Pearson correlation tests were used. Bone turnover markers were above the reference range for adult women in more than 80% of the adolescents, with no difference between C and G patients at T1. Increase in urinary N-telopeptide crosslinks of type I collagen and serum bone-specific alkaline phosphatase, markers of bone turnover, was seen during pregnancy ( p < 0.0001). Body composition did not differ between groups, but LS BMD, percentage of expected LS BMD, LS Z-score, percentage of expected TB BMD and TB Z-score were lower in G than C patients ( p < 0.05). TB BMD was positively correlated with LS BMD (r2 = 0.52). The inverse correlations between bone markers and LS BMD suggest that the increased bone turnover during pregnancy probably explains the low bone density after parturition. The impact on future peak bone mass must be studied. 相似文献
36.
37.
We found multimolecular antigenic mimicry of arthritogenic autoantigens and peptides from several other “self” or foreign antigens sharing amino acid sequence homologies. Many of these new mimotopes induced arthritis and/or uveitis upon immunization in Lewis rats, indicating a role for multiple antigens in the initiation of a certain autoimmune disease. 相似文献
38.
Frequency of and risk factors for allergy in primary school children: results of a population survey 总被引:1,自引:0,他引:1
Anna Maria Angioni Giovanni Fanciulli Carlo Corchia † 《Paediatric and perinatal epidemiology》1989,3(3):248-255
During May 1986, a survey to assess the frequency of allergic disorders was conducted among primary school children of Alghero, Sardinia, using a structured self-administered questionnaire. The following problems were investigated: allergic conjunctivitis, asthma, wheezing, allergic rhinitis, urticaria and eczema. Of the original 1823 questionnaires distributed, 1961 (92.8%) were completed by parents and returned. Overall, 238 children (14.1%) were reported to have shown at least one episode of one or more of the above and were regarded as 'allergic'. Among the potential risk factors investigated, statistically significant differences (P less than 0.05) between allergic and non-allergic children were only found for history of allergy in at least one parent (odds ratio, OR = 2.2) and exposure to passive smoking (OR = 1.4). 相似文献
39.
Andrew E. Springer Kayan Lewis Steven H. Kelder Maria E. Fernandez Cristina S. Barroso Deanna M. Hoelscher 《Journal of immigrant and minority health / Center for Minority Public Health》2010,12(5):769-780
Research on physical activity (PA) by level of acculturation in Hispanic children is limited and findings have been mixed.
We examined PA participation by primary language used with parents in a representative sample of 4th, 8th, and 11th grade
Texas public school students. Mixed-effects regression models were conducted using cross-sectional data from the 2004–2005
School Physical Activity and Nutrition Study (n = 22,049). Self-reported PA was compared among three language-ethnic groups: Spanish-Hispanic (SH) (referent); English-Hispanic
(EH); and English-Other (EO). EH and/or EO girls were generally between 1.25 and 2.58 [OR] times more likely to participate in PA across grade levels,
with the largest differences found for school sports in 8th grade girls. EH and EO 8th grade boys were 1.71 (CI: 1.40, 2.10)
and 2.06 (CI: 1.68, 2.51) times, respectively, more likely to participate in school sports. Findings indicate important disparities
in Spanish-speaking Hispanic children’s PA participation. 相似文献
40.
Carlos Ferrer Albiach Antonio Conde Moreno Marta Rodríguez Cordón Virginia Morillo Macías Ana Bouché Babiloni Inmaculada Beato Tortajada Ángel Sánchez Iglesias Alicia Francés Muñoz 《Clinical & translational oncology》2010,12(1):22-26
Hypoxia is related to poor prognosis because it is associated to chemo-and radioresistance. During recent years the evolution
of imaging methods like PET/CT and MRI has meant the appearance of new perspectives with direct implications in radiation
therapy. We discuss previous experiences in staging, planning and in the follow-up process with these techniques for measuring
tumour hypoxia. 相似文献