收费全文 | 4370篇 |
免费 | 370篇 |
国内免费 | 18篇 |
耳鼻咽喉 | 23篇 |
儿科学 | 128篇 |
妇产科学 | 61篇 |
基础医学 | 896篇 |
口腔科学 | 75篇 |
临床医学 | 410篇 |
内科学 | 971篇 |
皮肤病学 | 160篇 |
神经病学 | 421篇 |
特种医学 | 131篇 |
外科学 | 369篇 |
综合类 | 20篇 |
预防医学 | 332篇 |
眼科学 | 72篇 |
药学 | 320篇 |
中国医学 | 8篇 |
肿瘤学 | 361篇 |
2023年 | 38篇 |
2022年 | 111篇 |
2021年 | 185篇 |
2020年 | 102篇 |
2019年 | 124篇 |
2018年 | 159篇 |
2017年 | 125篇 |
2016年 | 143篇 |
2015年 | 155篇 |
2014年 | 170篇 |
2013年 | 212篇 |
2012年 | 342篇 |
2011年 | 312篇 |
2010年 | 182篇 |
2009年 | 149篇 |
2008年 | 214篇 |
2007年 | 236篇 |
2006年 | 179篇 |
2005年 | 210篇 |
2004年 | 149篇 |
2003年 | 150篇 |
2002年 | 149篇 |
2001年 | 73篇 |
2000年 | 60篇 |
1999年 | 57篇 |
1998年 | 30篇 |
1997年 | 32篇 |
1995年 | 28篇 |
1994年 | 16篇 |
1993年 | 19篇 |
1992年 | 31篇 |
1991年 | 30篇 |
1990年 | 52篇 |
1989年 | 44篇 |
1988年 | 35篇 |
1987年 | 29篇 |
1986年 | 28篇 |
1985年 | 32篇 |
1984年 | 17篇 |
1983年 | 21篇 |
1979年 | 26篇 |
1978年 | 19篇 |
1975年 | 14篇 |
1974年 | 16篇 |
1973年 | 13篇 |
1972年 | 18篇 |
1971年 | 14篇 |
1969年 | 13篇 |
1968年 | 23篇 |
1967年 | 14篇 |
Clinical presentation: Thirteen-year-old boy presented to the Otology clinic for auditory rehabilitation options. He has mild developmental delay, is non-verbal and communicates via American Sign Language. He was born with bilateral aural atresia and never wore amplification. On exam he has grade 1 microtia and complete ear canal atresia bilaterally. His behavioural hearing test shows profound sensorineural hearing loss of both ears. The computed tomography scan shows bilateral underdeveloped and completely opacified mastoid and middle ear, complete bony atresia of the ear canals, and an under-partitioned cochlea with poorly defined modiolus, among other abnormalities. The patient and his family were counselled on the available options as well as the need for any further studies.
Intervention: Counselling of patient and family.
Conclusion: While there have been reports in the literature of performing cochlear implantations in patients with a concurrent atresia and cochlear dysplasia, these were patients whose degree of inner ear anomalies was relatively minor and their prognosis of a good audiological outcome was favourable. The presented case is that of a patient for whom the surgical approach to the cochlea alone would be difficult. More importantly, his quality of life would not significantly improve in light of the predicted limited hearing and language development outcomes, given the severity of his inner ear abnormalities, limited communication abilities, prolonged period of deafness and developmental delays. 相似文献
Background
The etiological spectrum of pituitary stalk lesions (PSL) is wide and yet specific compared to the other diseases of the sellar and suprasellar region. Because of the pituitary stalk’s (PS) critical location and role, biopsies of these lesions are rarely performed, and their underlying pathology is often a conundrum for clinicians. A pituitary MRI in association with a clinical context can facilitate their diagnosis.Aim
To present the various causes of PSL—their clinical, hormonal, histopathological, and MRI characteristics in order to gain better insight into this pathology.Method
A retrospective observational study consisting of 53 consecutive patients with PSL of the mean age 32?±?4.2 years (range 6–67), conducted at the Department for Neuroendocrinology, Clinical Center of Serbia 2010–2018.Results
Congenital malformations were the most common cause of PSL in 25 of 53 patients (47.1%), followed by inflammatory (9/53; 16.9%) and neoplastic lesions (9/53; 16.9%). The exact cause of PSL was established in 31 (58.4%) patients, of whom 23 were with congenital PS abnormalities and 8 with histopathology of PSL (7 neoplastic and 1 Langerhans Cell Hystiocytosis). A probable diagnosis of PSL was stated in 12 patients (22.6%): 6 with lymphocytic panhypophysitis, while Rathke cleft cyst, tuberculosis, dissemination of malignancy in PS were each diagnosed in 2 patients. In 10 patients (18.8%), the etiology of PSL remained unknown.Conclusion
Due to the inability of establishing an exact diagnosis, the management and prognosis of PSL are difficult in many patients. By presenting a wide array of causes implicated in this condition, we believe that our study can aid clinicians in the challenging cases of this pathology.Concentrations of selected trace elements Ag, Co and V in raw milk sampled from four geographical regions in Croatia were measured. Silver, Co and V were detected above the limit of detection within the range of 9.52%–30.8%, 1.6%–12.1% and 12.4%–30.8%. Silver concentrations were not detected in milk samples from the Croatian Littoral and Mountainous Croatia (CL-MC) region. Similar Ag content was found in Southern, Eastern and Central Croatia. The lowest mean of Co and V of 33.2 and 83.8 µg kg?1 were found in the CL-MC region while the highest of 49.8 and 136.9 µg kg?1 was found in Central Croatia. There were no statistically significant differences in Ag, Co and V contents between the four regions. The estimated daily dietary intakes (EDI) of total mean and total 95th percentile values of Ag, Co and V showed lower values in comparison with available EFSA health-based limits.
相似文献