80岁以上股骨粗隆间骨折的手术治疗

目的 :探讨 80岁以上股骨粗隆间骨折患者的手术治疗及对其并发症的防治。方法 :2 5例患者采用Richard钉内固定治疗 ,并加强围手术期管理。结果 :随访 13～ 37月 ,疗效评定 :优 15例 ,良 8例 ,可 2例 ,优良率 92 % ,2年内原发疾病死亡 2例 ,无 1例发生内固定失败、髋内翻畸形等并发症。结论 :80岁以上股骨粗隆间骨折患者并发症较多 ,应严格掌握手术指征 ,加强围手术期管理 ,早期采用Richard钉等合适的内固定治疗     

Predictors of bone fractures in a single-centre cohort of hemodialysis patients: a 2-year follow-up study

International Urology and Nephrology - Bone involvement represents one of the complications of end-stage chronic kidney disease, with fractures being its major risk. The aim of our study was to...     

Anatomic implications of lesser trochanterplasty

Objective

The aim of this study was to measure the area of iliopsoas tendon attachment and the distance of sciatic nerve, medial circumflex femoral artery (MCFA) and quadratus muscle to lesser trochanter tip, before and after 5, 10, 15 mm depth excision of lesser trochanter.

Malignant triton tumor of the gluteal region in a patient unaffected by neurofibromatosis: A case report

Malignant triton tumor (MTT) is a rare variant of malignant peripheral nerve sheath tumor (MPNST) made up of both malignant schwannoma cells and malignant rhabdomyoblasts.A 26-years-old male patient was admitted with an asymptomatic gluteal mass. Magnetic resonance imaging showed heterogeneous soft tissue mass and he underwent open biopsy. Malignant peripheral nerve sheath tumor was diagnosed. He was given adjuvant chemotherapy following the removal of the tumor with hip disarticulation. The tumor was diagnosed as “malignant triton tumor” based on pathological examination including immunohistochemical studies. There were no signs of metastasis but recurrence was observed at 9 months follow up.MTT is usually associated with Neurofibromatosis 1 and located in head, neck region. In this case sporadic involvement of gluteal region and aggressive behavior of the lesion despite radical surgery was demonstrated.     

单细胞电泳法检测肿瘤患者化疗后淋巴细胞DNA损伤

应用单细胞电泳 (SCGE)检测肿瘤患者环磷酰胺化疗后外周血T淋巴细胞DNA损伤。在标准SCGE条件下应用彗星图象分析系统定量分析人T淋巴细胞DNA的损伤程度。彗星图象分析研究结果显示 ,肿瘤患者外周血T淋巴细胞DNA损伤明显强于正常对照组 ,肿瘤患者外周血T淋巴细胞拖尾动量为 10 42± 1 98,正常人群为 1 2 6± 0 77;两者差异极显著 (P <0 .0 1)。肿瘤患者化疗后T淋巴细胞的拖尾长度为 3 3 69± 7 56μm ,DNA损伤的百分比为 3 1 5± 5 46% ;正常人群T淋巴细胞的拖尾长度和DNA损伤的百分比分别为 16 2± 1 5μm和7 46± 1 15% ;两组数据相比差异极显著 (P <0 .0 1)。结论 :单细胞电泳可快速灵敏地检测细胞DNA损伤 ,能用于肿瘤化疗患者的流行病学观察。对于指导临床用药和预后也有指导意义     

教师期待效应理论在临床护理教学中的应用

[目的]教师期待效应理论应用于大专护生临床护理教学中，把教师的教育要求内化为护生的自觉行为，以使护生获得生动、活泼、主动的发展。[方法]2002级为对照组，按常规教学计划实习；2003级为实验组，在常规基础上增加初步调查、制定目标、护理实践、评估反馈四个环节，实习结束进行问卷调查和操作考核。[结果]实验组技术操作能力、对工作熟悉能力、沟通交流能力、实习心态均明显优于对照组（P〈0．05）。[结论]教师期待效应理论应用于大专护生临床护理教学有助于营造师生间有序、和谐的心理气氛，形成良性互动，使护生健康成长，进而提高了教学质量。     

Longitudinal Epiphyseal Bracket of the First Metatarsal Bone: Three Case Reports and a Review of the Literature

Longitudinal epiphyseal bracket (LEB) is a rare bone dysplasia of the tubular bones. Owing to an abnormal secondary ossification center, the affected bones can develop progressive shortening and angular deformity. The aim of our study was to provide an overview of the reported data regarding epidemiology and surgical procedures available for LEB of the first metatarsal bone in a pediatric population combined with a small case series. We report a retrospective case series of 3 nonsyndromic pediatric patients with different ages and with confirmed dysplasia of the first metatarsal bone. All patients presented with unilateral congenital hallux varus deformity and underwent surgical treatment. The radiographs and medical records were reviewed to evaluate the deformity characteristics, treatment, and clinical results. The mean patient age at initial surgery was 34 (range 12 to 63) months, and the median follow-up period was 46 (range 31 to 75)?months. Almost all specific radiographic measurements showed correction of the deformity, and each foot demonstrated functional and cosmetic improvement. A standardized literature search was performed to obtain studies of LEB of the first metatarsal bone in the pediatric population. From on our results and the current data available, surgical treatment should be tailored to the patient's age and radiographic stage of LEB. However, monitoring until skeletal maturity of the feet is necessary to assess the final results.     

乳腺小叶肿瘤组织学亚型及其分子病理学研究进展

第5版WHO乳腺肿瘤分类(2019), 将小叶瘤变定义为"起源于终末导管小叶单位(terminal ductal lobular units)失黏附上皮细胞的不典型增生, 伴或不伴有终末导管的派杰样播散"。小叶瘤变包括不典型小叶增生(atypical lobular hyperplasia)和小叶原位癌(lobular carcinoma in situ)。根据细胞形态将小叶原位癌细分为经典型小叶原位癌、旺炽型小叶原位癌和多形性小叶原位癌3种组织学亚型。近年来, 随着分子病理学不断发展, 对组织学形态特征的认识不断深入, 加深了对小叶瘤变及其亚型的研究和分析。本文将对小叶肿瘤各组织学亚型的临床病理学特征和分子病理学等方面进行综述。     

Does timing of surgery influence the long-term results of foot polydactyly treatment?

Background

There is an evident lack of research on timing of polydactyly surgery and its effects on treatment results.