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531.
Morrison Cassandra Dadar Mahsa Villeneuve Sylvia Ducharme Simon Collins D. Louis 《Age (Dordrecht, Netherlands)》2023,45(1):17-28
GeroScience - Increased age and cognitive impairment is associated with an increase in cerebrovascular pathology often measured as white matter hyperintensities (WMHs) on MRI. Whether WMH burden... 相似文献
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Anant Patil MD Jun Lu MD FAAD Martin Kassir MD Mahsa Babaei MD Mohamad Goldust MD 《Journal of Cosmetic Dermatology》2023,22(2):395-401
Introduction
Dermatomyositis is a rare autoimmune inflammatory condition affecting skin and muscles. The disease can be seen in both adults and children. It can be associated with malignancy. Considering involvement of skin in the disease, many patients consult dermatologists for its treatment. Hence, knowledge about its presentation, complications, prognosis, and treatment is necessary.Objective
The objective of this review article is to provide comprehensive information about treatment of dermatomyositis.Methods
In this review article, we reviewed the published literature on adult and juvenile dermatomyositis to highlight the treatment. Articles published in peer-reviewed journals including reviews, clinical trials, case series, and case reports published in electronic database (MEDLINE/PubMed) through January 2021, cross references of respective articles and trials from clinicaltrials.gov were included for qualitative analysis of the literature.Results
Treatment options for dermatomyositis include traditional immunosuppressive agents and immunomodulatory therapy. High-dose corticosteroids represent the first line of treatment while other immunosuppressive agents are also used, either in combination with or as an alternative to corticosteroids, after initial treatment failure. Some biological agents have been used for the treatment of dermatomyositis with variable responses.Conclusion
Although several treatment options are available, several questions remain unanswered about the optimal treatment of dermatomyositis. 相似文献534.
Mahsa Sepahvand Narges Yazdi Mohammad Rohani Maziar Emamikhah 《Radiology Case Reports》2022,17(2):303
Myelitis, including longitudinally extensive transverse myelitis (LTEM), is reported in more than forty patients after coronavirus disease 2019 (COVID-19). Among COVID-19 vaccines, only Oxford-AstraZeneca COVID-19 vaccine (AZD1222) has been associated with few cases of myelitis (1 LTEM). We report the first case of myelitis/LTEM after BBIBP-CorV/Sinopharm vaccine, interestingly presented as a hemicord syndrome. A 71-year-old male presented with left-side diplegia, right-side hemihyposthesis with facial sparing and impaired position sensation in left foot after vaccination with BBIBP-CorV. MRI revealed a longitudinal signal in left cervical hemicord. This is the first reported myelitis and LTEM with COVID-19 vaccines other than AZD1222. 相似文献
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Negar Piri MSc Yousef Moradi PhD Reza Ghanei Gheshlagh PhD Mahsa Abdullahi MD Eghbal Fattahi MD Farhad Moradpour PhD 《Journal of clinical hypertension (Greenwich, Conn.)》2023,25(2):146-157
This study aimed to investigate the validity of self-reported hypertension and related factors in the Dehgolan Prospective Cohort Study (DehPCS). Data were obtained from 3996 participants aged 35–70 years in the enrolment phase of DehPCS. Self-reported hypertension and sociodemographic factors were collected by well-trained interviewers before hypertension diagnosis based on the reference criteria. The history of anti-hypertensive medication use and/or systolic blood pressure ≥140 (mmHg), or diastolic blood pressure ≥90 (mmHg) were considered as hypertension. Disagreement between self-reported and reference measures was assessed using sensitivity, specificity, positive, and negative predictive values (PPV and NPV), and kappa values. Binary and multinomial logistic regressions were used to investigate the correlates of validity of self-reported hypertension. The hypertension prevalence based on self-reports and the reference criteria was 19.49% and 21.60%, respectively. An acceptable percentage of kappa agreement value of 68.7% and relatively good overall agreement of 89.8% were found. Self-reported hypertension was guaranteed moderate sensitivity of 72.0% and high specificity of 94.5%, as well as the NPV and PPV of 92/7% and 77/9%, respectively. The chances of false-positive and false-negative reporting increased with older age, higher BMI, and a family history of hypertension. Being female, older age, higher BMI, concurrent diabetes, and stronger family ties to hypertension patients significantly increased the chance of reporting true positives relative to true negatives. Although, self-reported hypertension has an acceptable validity and can be used as a valid tool for screening epidemiological studies, it needs to be investigated because its validity is affected by age, gender, family history of hypertension, and other socio-demographic characteristics. 相似文献
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Ali Ataei Mahsa Tahsili Golsa Hayadokht Maziar Daneshvar Shabnam Mohammadi Nour Asma Soofi Alireza Masoudi Maryam Kabiri Mohammad Natami 《Chemical biology & drug design》2023,102(3):640-652
Neuroblastoma (NB) is the third most prevalent tumor that mostly influences infants and young children. Although different treatments have been developed for the treatment of NB, high-risk patients have been reported to have low survival rates. Currently, long noncoding RNAs (lncRNAs) have shown an attractive potential in cancer research and a party of investigations have been performed to understand mechanisms underlying tumor development through lncRNA dysregulation. Researchers have just newly initiated to exhibit the involvement of lncRNAs in NB pathogenesis. In this review article, we tried to clarify the point we stand with respect to the involvement of lncRNAs in NB. Moreover, implications for the pathologic roles of lncRNAs in the development of NB have been discussed. It seems that some of these lncRNAs have promising potential to be applied as biomarkers for NB prognosis and treatment. 相似文献
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Parinaz Sedighi Seyedeh Taravat Sadrosadat Mahsa Movahedi Iraj Sedighi 《Clinical Case Reports》2022,10(4)
We report a four‐month‐old girl with a right thigh swelling, an eight‐month‐old girl with a left thigh swelling, and a five‐month‐old boy with a left thigh swelling with the final diagnosis of BCG‐induced cold abscess as a result of erroneous injection of BCG vaccine into the infants’ thigh muscle. 相似文献