全文获取类型
收费全文 | 133693篇 |
免费 | 13458篇 |
国内免费 | 9175篇 |
专业分类
耳鼻咽喉 | 1020篇 |
儿科学 | 1851篇 |
妇产科学 | 1416篇 |
基础医学 | 12448篇 |
口腔科学 | 2569篇 |
临床医学 | 18802篇 |
内科学 | 16073篇 |
皮肤病学 | 1630篇 |
神经病学 | 4737篇 |
特种医学 | 4571篇 |
外国民族医学 | 44篇 |
外科学 | 10358篇 |
综合类 | 29262篇 |
现状与发展 | 40篇 |
一般理论 | 8篇 |
预防医学 | 12755篇 |
眼科学 | 3640篇 |
药学 | 15443篇 |
234篇 | |
中国医学 | 10737篇 |
肿瘤学 | 8688篇 |
出版年
2024年 | 546篇 |
2023年 | 2064篇 |
2022年 | 5217篇 |
2021年 | 6546篇 |
2020年 | 5380篇 |
2019年 | 3982篇 |
2018年 | 4061篇 |
2017年 | 4520篇 |
2016年 | 3792篇 |
2015年 | 6315篇 |
2014年 | 7752篇 |
2013年 | 7967篇 |
2012年 | 11918篇 |
2011年 | 12577篇 |
2010年 | 9680篇 |
2009年 | 8047篇 |
2008年 | 8832篇 |
2007年 | 8513篇 |
2006年 | 7510篇 |
2005年 | 6661篇 |
2004年 | 4440篇 |
2003年 | 4094篇 |
2002年 | 3341篇 |
2001年 | 2603篇 |
2000年 | 2180篇 |
1999年 | 1671篇 |
1998年 | 969篇 |
1997年 | 997篇 |
1996年 | 750篇 |
1995年 | 633篇 |
1994年 | 588篇 |
1993年 | 342篇 |
1992年 | 320篇 |
1991年 | 304篇 |
1990年 | 267篇 |
1989年 | 209篇 |
1988年 | 202篇 |
1987年 | 179篇 |
1986年 | 115篇 |
1985年 | 90篇 |
1984年 | 45篇 |
1983年 | 41篇 |
1982年 | 15篇 |
1981年 | 11篇 |
1980年 | 7篇 |
1979年 | 14篇 |
1978年 | 2篇 |
1975年 | 4篇 |
1974年 | 3篇 |
1973年 | 5篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
Jianhua Yan Zhongyao Wu Eye Hospital Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China 《眼科学报》2003,19(3):174-175
Purpose:To report a rare sign, paracentral corneal dellen that developed in a middleaged female patient with Graves ophthalmopathy.Methods:A paracentral corneal dellen developed in the left eye in a 42-year-old woman who was diagnosed as Graves ophthalmopathy. The patient had remarkable upper eyelid retraction, upper eyelid lag and upward motility restriction. The Graves ophthalmopathy was classified as Grade Ⅳ according to NOSPECS classification.Results:Local artificial tear film and 0.3% Tobramycin eye drops were administered to both eyes.Twenty-four hours later, the left corneal dellen disappeared.Conclusions:Graves ophthalmopathy can lead to paracentral corneal dellen because of severe upper eyelid retraction and upward motility restriction of the eye in spite of the lack of lagophthalmos. Artificial tear drop and antibiotic eye drop therapy helped even though the patient did not have corneal exposure. Eye Science 2003;19:174-175. 相似文献
92.
目的探讨特发性震颤(essential tremor,ET)的临床特点。方法回顾性分析98例ET患者的临床资料。结果98例ET中男56例,女42例。发病年龄6~72岁,平均43.08±18.18岁。病程1~48年,平均14.04±11.39年。48例(48.98%)患者有阳性家族史。临床主要表现为单症状的姿势性震颤,累及部位依次为手98例(100%)、头38例(38.78%)、下肢28例(28.57%)、咽喉部16例(16.33%)、下颏10例(10.20%)等。64例患者做了饮酒试验,其中58例(90.63%)有酒精反应。84.62%的患者服用盐酸阿罗洛尔治疗有效。结论特发性震颤的临床表现以单症状姿势性震颤为主,手及头部受累明显,多数患者对酒精有反应,盐酸阿罗洛尔治疗有效。 相似文献
93.
94.
NADPH-Diaphorase-Positive Neurons in Primate Cerebral Cortex Colocalize with GABA and Calcium-Binding Proteins 总被引:3,自引:3,他引:0
Neurons in the monkey cerebral cortex containing nicotinamideadenine dinucleotide phosphate-diaphorase (NADPH-d) can he dividedinto two distinct types, both nonpyramidal. Type I neurons havea large soma (diameter 2050 µm), a dense NADPH-dhistochemical reaction. and are distributed throughout the cortex,but mainly in the subcortical white matter, and are mostly aspiny.Type II cells have a small soma (< 20 µm) with lightNADPH-d reactivity and are distributed primarily in the supragranularlayers, particularly layers II and upper III. The numericaldensity of type II cells is much greater than that of type I.Type I neurons also stain for GABA and a few intracortical typeI cells contain calbindin. All type II cells found here arecolocalized with both GABA and calbindin. Neither type I nortype II cells are stained for parvalbumin. Together with previous observations that almost all corticalNADPH-d cells in various subprimates are like type I cells,we suggest that type II cells may form a group of NADPH-d-richneurons differentiated in higher mammalian cortex from a subpopulationof calbindin-containing GABAergic interneurons, and these nitricoxide-synthesizing cells may play a role in control of intracorticalneuronal activity characteristic of higher cerebral functionsin advanced mammals. 相似文献
95.
96.
预移植在胚胎移植中的意义 总被引:2,自引:0,他引:2
目的 :评价预移植在胚胎移植中的作用。 方法 :在超声波引导下胚胎移植 114个周期 ,其中 10 1个周期进行预移植。比较预移植与未预移植周期临床妊娠率和胚胎种植率 ;按预移植与实际胚胎放置深度差值分组 ,并比较两组妊娠率和胚胎种植率。 结果 :预移植周期与未预移植周期临床妊娠率和种植率统计学差异无显著性(5 9.4 1%和 6 1.5 4 % ,35 .81%和 31.4 3% ,P均 >0 .0 5 ) ;按预移植与实际胚胎放置深度差值分组后 ,两组妊娠率和种植率统计学差异也无显著性 (6 1.5 4 %和 5 8.6 7% ,4 0 .79%和 34.0 9% ,P均 >0 .0 5 )。 结论 :在胚胎移植技术中 ,预移植不能准确指引胚胎移植深度 相似文献
97.
Recapitulation of fast skeletal muscle development in zebrafish by transgenic expression of GFP under the mylz2 promoter. 总被引:1,自引:0,他引:1
Bensheng Ju Shang Wei Chong Jiangyan He Xukun Wang Yanfei Xu Haiyan Wan Yan Tong Tie Yan Vladimir Korzh Zhiyuan Gong 《Developmental dynamics》2003,227(1):14-26
A 1,934-bp muscle-specific promoter from the zebrafish mylz2 gene was isolated and characterized by transgenic analysis. By using a series of 5' promoter deletions linked to the green fluorescent protein (gfp) reporter gene, transient transgenic analysis indicated that the strength of promoter activity appeared to correlate to the number of muscle cis-elements in the promoter and that a minimal -77-bp region was sufficient for a relatively strong promoter activity in muscle cells. Stable transgenic lines were obtained from several mylz2-gfp constructs. GFP expression in the 1,934-bp promoter transgenic lines mimicked well the expression pattern of endogenous mylz2 mRNA in both somitic muscle and nonsomitic muscles, including fin, eye, jaw, and gill muscles. An identical pattern of GFP expression, although at a much lower level, was observed from a transgenic line with a shorter 871-bp promoter. Our observation indicates that there is no distinct cis-element for activation of mylz2 in different skeletal muscles. Furthermore, RNA encoding a dominant negative form of cAMP-dependent protein kinase A was injected into mylz2-gfp transgenic embryos and GFP expression was significantly reduced due to an expanded slow muscle development at the expense of GFP-expressing fast muscle. The mylz2-gfp transgene was also transferred into two zebrafish mutants, spadetail and chordino, and several novel phenotypes in muscle development in these mutants were discovered. 相似文献
98.
Zheng Qi-xin Zhu Tong-bai Du Jing-yuan Hong Guang-xiang Li Shi-pu Yan Yun-hua Zhang En-dang 《华中科技大学学报(医学英德文版)》1992,12(3):173-178
Summary The authors have prepared the artificial bone of porous tricalcium phosphate ceramics according to an appropriate formula
and manufacturing technology. Physical and chemical testing shows that it possesses several distinguishing features: the communicating
pores and macro/micropores; mean pore size, 380 μm (from 240 μm to 510 μm); porosity, 46.4 %; and compressive strength, 97.4
kg/cm2. It consists of CaO (49.09 %) and P2O5 (48.84 %). The testing of its biocompatibility shows that it is devoid of systemic or local toxicity, and free of irritation
or foreign body response in tissues, and it does not result in hemolysis or mutation. The new bone readily grows into its
pores with direct contact to the implanted material. 11 cases of bone defects were treated with this artificial bone with
satisfactory results. 相似文献
99.
100.
五型病毒性肝炎的暴露因素与临床表现的比较 总被引:2,自引:1,他引:1
比较急性病毒性肝炎患者感染打危险因素,同时比较五型肝炎的症状和体征。连续收集急性病毒性肝炎患者血清293份,用ELISA法检测了五型肝炎病毒的病原学指标,并进行了流赞美同学调查。暴露因素:丙肝的肠道外暴露外明显多于甲肝;甲肝和戊肝有较高的“甲肝”患者接触史;乙肝,丙肝和丁肝有高的“乙肝”接触史,与甲肝,戊肝相比差异显著。 相似文献