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排序方式: 共有10000条查询结果,搜索用时 234 毫秒
981.
982.
Ignacio G��mez-Ochoa Pablo G��mez-Ochoa Francisco G��mez-Casal Encarna Cativiela Luis Larrad-Mur 《Rheumatology international》2011,31(10):1283-1289
The clinical use of pulsed electromagnetic fields (PEMF) in osteoarticular pathology is widely extended, although the mechanisms
involved are unknown. The aim of this study was to evaluate the action of a new protocol of treatment with PEMF on liquid
medium cultures of fibroblast-like cells derivates of mononuclear peripheral blood cells. Fibroblast-like cells growth was
obtained in liquid medium culture from mononuclear cells (MNC) of human peripheral blood. The PEMF irradiation protocol included
an intensity of 2.25 mT, a frequency of 50 Hz and an application time of 15 min on days 7, 8 and 9 of cell culture. Immunophenotype
was performed with specific heterologous monoclonal antibodies for each cell receptor (Vimentin, Cytokeratin, CD34, CD41,
CD61 and CD68). The cytokines’ production was determined in the supernatant of the culture medium by means of the Luminex
technology. The immunophenotype did not show any statistical difference on comparing treated against non-treated cell cultures
on any of the days. In the treatment cell population, the proinflammatory cytokines, IL-1β and TNF-α showed a significant
decrease on days 14 and 21 of the culture, whilst IL-10 increased significantly on day 21. It is concluded that PEMF irradiation
does not alter the cell immunophenotype of the fibroblast-like cell population, but does provoke a decrease in the production
of inflammatory-type cytokines (IL-1β, TNF-α) and an increase in cytokines of lymphocytic origin (IL-10). These facts coincide
with the chronology of the clinical effect undergone by patients with osteoarticular pathology after PEMF irradiation. 相似文献
983.
The turbinal flap: an additional option for anterior skull base reconstruction. Cadaveric feasibility study and case report
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![点击此处可从《International forum of allergy & rhinology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
984.
Predictive factors for anemia response to erythropoiesis‐stimulating agents in myelofibrosis
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![点击此处可从《European journal of haematology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Juan‐Carlos Hernández‐Boluda Juan‐Gonzalo Correa Regina García‐Delgado Joaquín Martínez‐López Alberto Alvarez‐Larrán María‐Laura Fox Valentín García‐Gutiérrez Manuel Pérez‐Encinas Francisca Ferrer‐Marín María‐Isabel Mata‐Vázquez José‐María Raya Natalia Estrada Silvia García Ana Kerguelen María‐Antonia Durán Manuel Albors Francisco Cervantes 《European journal of haematology》2017,98(4):407-414
985.
986.
987.
988.
Association between disease activity and quality of life in ulcerative colitis: Results from the CRONICA‐UC study
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![点击此处可从《Journal of gastroenterology and hepatology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
989.
990.
Victoria Alegría‐Landa Margarita Jo‐Velasco Lucía Prieto‐Torres Luis Requena 《Journal of cutaneous pathology》2017,44(5):504-508
Folliculo‐sebaceous hamartomas comprise a series of entities whose boundaries are imprecise. We present the clinical case of a folliculo‐sebaceous cystic hamartoma of genital localization where the diagnosis was established based on the epithelial proliferation, but mostly, on the characteristic stroma. Because this lesion lacked of the cystic component, we mention the most frequent differential diagnoses and review the literature of the few cases published on this infrequent localization. 相似文献