冲击式二级采样对呼吸粉尘与总粉尘浓度比值的影响

为了验证冲击式二级粉尘采样对呼吸性粉尘与总粉尘浓度比值的影响，作者采用瞬时定点采样方法测定作业场所空气中呼吸性粉尘浓度与总粉尘浓度。结果表明，在采样体积相同的条件下，呼吸性粉尘的比值与总粉尘浓度间具有较好的从属共变关系（ｒ＞０．８），呼吸性粉尘的比值随着总粉尘浓度的升高而相应增大     

多索茶碱及其片剂的高效液相色谱分析

多索茶碱及其片剂的高效液相色谱分析刘春胜，何秀峰，王云萍，谷士杰，周同惠（中国医学科学院、中国协和医科大学药物研究所，北京１０００５０）多索茶碱（ｄｏｘｏｆｙｌｌｉｎｅ）是用于治疗支气管哮喘合并支气管痉挛的慢性阻塞性肺部疾病的新一代黄嘌吟衍生物，其药...     

Catabolic effect in premature infants with early dexamethasone treatment

To evaluate the catabolic effects of dexamethasone therapy on protein metabolism, amino acid concentrations and urinary 3-methylhistidine (3MH) were measured in 28 premature infants who were included in a double-blind controlled study using early dexamethasone therapy in the prevention of bronchopulmonary dysplasia. Fifteen infants received dexamethasone (0.5mg/kg/day i.v.) and 13 infants received normal saline as control. Heparinized venous blood samples for amino acid analysis were obtained before the study and again at day 5 after starting the study. Urinary 3MH was measured on days 1, 3, 5, 7, 14, 21, and 28 of treatment. A substantial increase in amino acid concentrations was observed in infants receiving dexamethasone. Alanine, glutamine, citrulline, ornithine and cystine concentrations increased twofold or more. The 3MH:creatinine ratio was increased in the treated group. These metabolic effects were most likely due to an increase in protein catabolism.     

应用微波技术切割睑球粘连22例

目的探讨微波热凝切割睑球粘连的治疗效果。方法随机抽取１９９５年１月～１９９７年１２月我科应用微波治疗睑球粘连２２例进行回顾性总结。结果２２例轻、中、重度睑球粘连患者，经１～４次热凝切割，均痊愈。结论微波技术切割睑球粘连操作简便易行，是一种较为理想的治疗方法。     

Experimental studies of electroacupuncture on ventricular fibrillation threshold in rats with acute ischemic myocardium

Summary By ligating the proximate left anterior descend (LAD) of coronary artery and inducing the ventricular fibrillation with electrical stimulation, the preventive effects of electroacupuncture (EA) on ventricular fibrillation were observed. The results showed that the ventricular fibrillation threshold (VFT) of rats with acute ischemic myocardium was raised after acupuncturing some acupoints, which could prevent the occurrence of ventricular fibrillation. Furthermore, the combination of EA and propranolol could enhance the VFT effectively, and they showed a good synergistic effect. This project was supported by grants from National Natural Science Foundation of China (No. 3870563).     

山东省潍坊市乡村卫生组织一体化管理调查

“乡村一体化管理”是农村基层卫生组织主动适应社会主义市场经济发展而创造的一种基层卫生机构管理体制。几年来各地的改革实践已经证明:这一新型的管理体制对于强化乡镇卫生院行政管理职能、调整组织结构和服务功能、优化卫生资源、提高综合效益有着积极的促进作用,是现阶段农村乡镇卫生院求生存、促发展的一条有效途径。本文作者受卫生部委托对山东省潍坊市一体化管理做了实地考察。对潍坊市立足实际、因地制宜地开展多种形式的一体化管理所取得的成功经验给予了充分肯定,并对此种管理体制实施的效果及存在的问题做了客观分析,提出了政策性建议,是迄今为止对“乡村一体化管理”所做的全面、系统、科学的总结和评价,旨在启发各地在实施“一体化管理”的过程中,不断兴利除弊、大胆创新,在实践中开拓新思路,迈出新步伐,探索出一条适应我国农村卫生事业建设和发展的新路子。     

尼尔雌酵防治绝经后骨质疏松症和血脂紊乱的研究进展

本文综述了新型长效雌三醇衍生物－尼尔雌醇的药理作用、代谢动力学、防治绝经后骨质疏松症和血脂紊乱实验及临床研究的进展。     

纵隔软组织肿瘤23例临床病理分析

本科手术治疗纵隔软组织肿瘤２３例，占同期手术治疗纵隔肿瘤３９０例的５．９％，年龄３５岁以下者１７例，占７３．９％。男女之比为４．８：１（１９／４），本病的临床及Ｘ线表现缺乏特异性，确诊有赖于术后病理学检查。本组中良性肿瘤１５例（６５．２％），恶性肿瘤８例（３４．８％），手术治疗２４例次，肿瘤切除率为９１．７％（２２／２４），手术为首选的治疗方法。     

支气管哮喘患者早期病理形态学改变

目的：应用电镜对支气管哮喘患者以气管粘膜进行观察，了解支气管病理形态学改变。方法：对持续咳嗽３￣１２个月的１２例哮喘患者，１周内未使用类固醇、妥痉平湍及抗组织胺类药物，行支气管镜常规检查，每例患者取２￣３块病理组织行电镜检查。结果：电镜下观察早期哮喘患者已具备了哮喘病理形态学改变，并且还发现线粒体变性、粗面内质网（ＲＥＲ）扩张及髓磷体的出现和轻度钙过载。意义：即使是早期哮喘患者的病理形态学改变也与