全文获取类型
收费全文 | 530176篇 |
免费 | 27643篇 |
国内免费 | 495篇 |
专业分类
耳鼻咽喉 | 6681篇 |
儿科学 | 16924篇 |
妇产科学 | 12539篇 |
基础医学 | 92634篇 |
口腔科学 | 12349篇 |
临床医学 | 48510篇 |
内科学 | 95460篇 |
皮肤病学 | 11874篇 |
神经病学 | 34016篇 |
特种医学 | 19758篇 |
外国民族医学 | 53篇 |
外科学 | 78110篇 |
综合类 | 7611篇 |
现状与发展 | 2篇 |
一般理论 | 107篇 |
预防医学 | 38550篇 |
眼科学 | 11940篇 |
药学 | 41418篇 |
1篇 | |
中国医学 | 1127篇 |
肿瘤学 | 28650篇 |
出版年
2021年 | 3898篇 |
2018年 | 5736篇 |
2017年 | 4128篇 |
2016年 | 4872篇 |
2015年 | 5365篇 |
2014年 | 7118篇 |
2013年 | 10507篇 |
2012年 | 15591篇 |
2011年 | 17406篇 |
2010年 | 9958篇 |
2009年 | 8826篇 |
2008年 | 15720篇 |
2007年 | 17452篇 |
2006年 | 16951篇 |
2005年 | 16267篇 |
2004年 | 15884篇 |
2003年 | 15266篇 |
2002年 | 14784篇 |
2001年 | 22432篇 |
2000年 | 22974篇 |
1999年 | 18922篇 |
1998年 | 5232篇 |
1997年 | 4364篇 |
1996年 | 4397篇 |
1995年 | 4124篇 |
1992年 | 14414篇 |
1991年 | 15821篇 |
1990年 | 15951篇 |
1989年 | 15626篇 |
1988年 | 14308篇 |
1987年 | 14200篇 |
1986年 | 13168篇 |
1985年 | 12691篇 |
1984年 | 9394篇 |
1983年 | 8000篇 |
1982年 | 4178篇 |
1979年 | 8937篇 |
1978年 | 6382篇 |
1977年 | 5149篇 |
1976年 | 5504篇 |
1975年 | 6614篇 |
1974年 | 7419篇 |
1973年 | 7158篇 |
1972年 | 6600篇 |
1971年 | 6309篇 |
1970年 | 5888篇 |
1969年 | 5470篇 |
1968年 | 5162篇 |
1967年 | 4623篇 |
1966年 | 3967篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
22.
In rare cases the usage of the internal thoracic vessels as recipient vessels in reconstructive surgery of the head and neck region with free tissue transfer is a challenging but valid alternative if local recipient vessels are unusable. 相似文献
23.
Parupudi V J Sriram Guduru V Rao Nageshwar D Reddy 《Indian journal of gastroenterology》2006,25(1):39-41
Endoscopic clips have been used mainly for control of gastrointestinal (GI) bleeding and occasionally for closure of GI perforations. However, closure of spontaneous esophageal perforation (Boerhaave's syndrome) by clipping has not been reported. We described successful non-surgical closure of spontaneous esophageal perforation by endoscopic clipping in a patient with bilateral pyopneumothorax and septicemia. 相似文献
24.
JM Martín† L Calduch† C Monteagudo‡ I Molina† D Ramón† V Alonso† E Jordᆠ《Journal of the European Academy of Dermatology and Venereology》2006,20(4):428-431
Cutaneous plasmacytosis is a rare disorder characterized by a benign proliferation of mature plasma cells that appears as multiple dark-brown to purplish skin lesions, often associated with polyclonal hypergammaglobulinaemia. We present the case of a 55-year-old Caucasian man who suffered from a cutaneous plasmacytosis associated with two different carcinomas. Cutaneous plasmacytosis seems to be a reactive process because most cases reported are not associated with any apparent underlying disease. Nevertheless, because few reported cases were associated with malignancies, screening of additional neoplasms would be justified. 相似文献
25.
26.
Published data devoted to making and characterization of the properties of polymeric wound dressings with proteolytic action
are reviewed. These data are indicative of individual dependence of the physicochemical properties, activity, and stability
of each particular enzyme on the type of polymer matrix and the method of immobilization. In order to obtain wound dressings,
which are active in physiological medium and retain their activity upon sterilization, it is necessary to optimize the composition
and characteristics of a polymer matrix and the enzyme included into its structure.
__________
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 40, No. 8, pp. 24–28, August, 2006. 相似文献
27.
A survey of plants used as wild vegetables was conducted in four districts of Botswana in August and September 2005. The objective was to determine which wild plants were used as vegetables in the study area, and to document their cooking and preservation methods. Fourteen species representing seven families were mentioned as wild vegetables. In addition, six species from four families had other uses in traditional medicine. The implications of the documented processing methods on the retention of nutrients in the vegetables are discussed. 相似文献
28.
BCR-ABL activity and its response to drugs can be determined in CD34+ CML stem cells by CrkL phosphorylation status using flow cytometry. 总被引:2,自引:0,他引:2
A Hamilton L Elrick S Myssina M Copland H J?rgensen J V Melo T Holyoake 《Leukemia》2006,20(6):1035-1039
In chronic myeloid leukaemia, CD34(+) stem/progenitor cells appear resistant to imatinib mesylate (IM) in vitro and in vivo. To investigate the underlying mechanism(s) of IM resistance, it is essential to quantify Bcr-Abl kinase status at the stem cell level. We developed a flow cytometry method to measure CrkL phosphorylation (P-CrkL) in samples with <10(4) cells. The method was first validated in wild-type (K562) and mutant (BAF3) BCR-ABL(+) as well as BCR-ABL(-) (HL60) cell lines. In response to increasing IM concentration, there was a linear reduction in P-CrkL, which was Bcr-Abl specific and correlated with known resistance. The results were comparable to those from Western blotting. The method also proved to be reproducible with small samples of normal and Ph(+) CD34(+) cells and was able to discriminate between Ph(-), sensitive and resistant Ph(+) cells. This assay should now enable investigators to unravel the mechanism(s) of IM resistance in stem cells. 相似文献
29.
F Pitta T Troosters V S Probst M A Spruit M Decramer R Gosselink 《The European respiratory journal》2006,27(5):1040-1055
Accurate assessment of the amount and intensity of physical activity in daily life is considered very important due to the close relationship between physical activity level, health, disability and mortality. For this reason, assessment of physical activity in daily life has gained interest in recent years, especially in sedentary populations, such as patients with chronic obstructive pulmonary disease (COPD). The present article aims to compare and discuss the two kinds of instruments more commonly used to quantify the amount of physical activity performed by COPD patients in daily life: subjective methods (questionnaires, diaries) and motion sensors (electronic or mechanical methods). Their characteristics are summarised and evidence of their validity, reliability and sensitivity is discussed, when available. Subjective methods have practical value mainly in providing the patients' view on their performance in activities of daily living and functional status. However, care must be taken when using subjective methods to accurately quantify the amount of daily physical activity performed. More accurate information is likely to be available with motion sensors rather than questionnaires. The selection of which motion sensor to use for quantification of physical activity in daily life should depend mainly on the purpose of its use. 相似文献
30.
Abstract The pain of cluster headache attacks is severe, excruciating and selectively responsive to subcutaneous sumatriptan. Serious
cardiovascular events attributed to sumatriptan are extremely rare and have most often been reported in patients at significant
cardiovascular risk, or in overt cardiovascular disease. They also have occurred, however, in patients without evidence of
cardiovascular disease. We describe a 42-year-old man with episodic cluster headache without history of coronary artery disease
who was admitted to our coronary care unit for acute myocardial infarction after 3 h of subcutaneous injection of sumatriptan.
During hospitalisation cluster headache attacks were successfully treated with e.v. indomethacin. 相似文献