全文获取类型
收费全文 | 8794篇 |
免费 | 530篇 |
国内免费 | 38篇 |
专业分类
耳鼻咽喉 | 122篇 |
儿科学 | 162篇 |
妇产科学 | 153篇 |
基础医学 | 1096篇 |
口腔科学 | 858篇 |
临床医学 | 679篇 |
内科学 | 1979篇 |
皮肤病学 | 199篇 |
神经病学 | 648篇 |
特种医学 | 264篇 |
外科学 | 901篇 |
综合类 | 24篇 |
一般理论 | 4篇 |
预防医学 | 995篇 |
眼科学 | 159篇 |
药学 | 683篇 |
中国医学 | 97篇 |
肿瘤学 | 339篇 |
出版年
2023年 | 80篇 |
2022年 | 188篇 |
2021年 | 345篇 |
2020年 | 246篇 |
2019年 | 288篇 |
2018年 | 349篇 |
2017年 | 223篇 |
2016年 | 251篇 |
2015年 | 318篇 |
2014年 | 454篇 |
2013年 | 472篇 |
2012年 | 668篇 |
2011年 | 813篇 |
2010年 | 382篇 |
2009年 | 315篇 |
2008年 | 543篇 |
2007年 | 546篇 |
2006年 | 394篇 |
2005年 | 402篇 |
2004年 | 309篇 |
2003年 | 292篇 |
2002年 | 243篇 |
2001年 | 168篇 |
2000年 | 145篇 |
1999年 | 121篇 |
1998年 | 47篇 |
1997年 | 45篇 |
1996年 | 40篇 |
1995年 | 19篇 |
1994年 | 17篇 |
1993年 | 18篇 |
1992年 | 44篇 |
1991年 | 66篇 |
1990年 | 50篇 |
1989年 | 45篇 |
1988年 | 39篇 |
1987年 | 41篇 |
1986年 | 37篇 |
1985年 | 41篇 |
1984年 | 30篇 |
1983年 | 29篇 |
1982年 | 18篇 |
1981年 | 13篇 |
1980年 | 15篇 |
1979年 | 17篇 |
1978年 | 12篇 |
1973年 | 14篇 |
1970年 | 13篇 |
1968年 | 10篇 |
1966年 | 13篇 |
排序方式: 共有9362条查询结果,搜索用时 15 毫秒
101.
102.
Ana Dorcas de Melo Inagaki Cristina Gardonyi Carvalheiro Rosana Cipolotti Ricardo Queiroz Gurgel Dayse Alves Rocha Kariny Souza Pinheiro Raquel Melo Araújo Dorothy Ribeiro Resende Lima Jacques Leon Winandy Marisa Márcia Mussi‐Pinhata 《Tropical medicine & international health : TM & IH》2012,17(11):1349-1355
Objectives To estimate, by neonatal screening, the birth prevalence of congenital toxoplasmosis among live‐born infants in Sergipe state, Brazil, and to investigate the clinical features of affected infants. Methods Dried blood spot specimens obtained from 15 204 neonates were assayed for the presence of anti‐T. gondii IgM antibodies. Duplicate retesting was done in infants with positive and borderline results. Confirmatory testing in peripheral blood samples consisted of testing for anti‐T. gondii IgG and IgM in infants and mothers. Those with possible congenital toxoplasmosis were evaluated and followed up to a median age of 20 months. Congenital infection was confirmed in the presence of persisting anti‐T. gondii IgG antibodies beyond 12 months of age. All infants with confirmed infection were treated with pyrimethamine, sulfadiazine and folinic acid for 1 year. Results Fifty‐three infants had detectable IgM in dried blood spot specimens. Confirmatory testing was reactive in 39/50, of which, 38 completed follow‐up. Six of 15 204 newborns were diagnosed with congenital toxoplasmosis, resulting in an estimated birth prevalence of four per 10 000 [CI 95% 1.4–8.0]. Four infants (67%) showed signs of congenital toxoplasmosis in their first year of life; three (75%) had retinochoroidal scars, and one had cerebral calcifications. Two infants remained asymptomatic until 20 months of age. Conclusions The birth prevalence of congenital toxoplasmosis is high in the Brazilian state of Sergipe, with most of the infants showing ocular lesions. Preventive measures are strongly warranted. 相似文献
103.
Orlando Oliveira de Morais érica Freitas Lima Lemos Márcia Carolline dos Santos Sousa Ciro Martins Gomes Izelda Maria Carvalho Costa Carmen Déa Ribeiro de Paula 《Anais brasileiros de dermatologia》2013,88(2):238-242
Melasma represents a pigmentary disorder that is difficult to treat. This study aims
to broadly review the use of ablative lasers (Er:YAG and CO2) in the treatment of
melasma, presenting the level of evidence of studies published to date. A total of 75
patients were enrolled in four case series studies (n=39), one controlled clinical
trial (n=6) and one randomized controlled clinical trial (n=30). Studies on the
Er:YAG laser showed better results with the use of short square-shaped pulses, which
determined low rates of post-inflammatory hyperpigmentation and long-lasting
maintenance of results. Likewise, studies on the CO2 laser proved the benefits of
short pulse duration along with low-density energy. Post-treatment maintenance with
the use of antipigmenting creams was necessary and effective to sustain long-term
results. Ablative lasers may represent another useful and effective tool against
melasma. Postinflammatory hyperpigmentation and difficulty in sustaining long-term
results still represent the main limitations to a broader use of ablative lasers.
Based on actual evidence, the use of this technology should be restricted to patients
with recalcitrant disease. Further studies will help establish optimal laser
parameters and treatment regimens. 相似文献
104.
Ewelyne M. de Lima Andrews M. do Nascimento Girlandia A. Brasil Placielle F. Filete Ieda C. Kalil Dominik Lenz Denise C. Endringer Nazaré S. Bissoli Tadeu U. de Andrade 《Fundamental & clinical pharmacology》2016,30(4):316-326
This study evaluated the effects of the isolated use of a low dose of methyltestosterone (MT) on cardiovascular reflexes and hormonal levels and its geno‐ and cytotoxic safety in ovariectomized rats. Female Wistar rats were divided into four groups (n = 6), respectively: SHAM (received vehicle methylcellulose 0.5%), SHAM + MT (received MT 0.05 mg/kg), OVX (received vehicle), and OVX + MT (received MT). Twenty‐one days after ovariectomy, treatment was given orally daily for 28 days. The Bezold–Jarisch reflex (BJR) was analyzed by measuring the bradycardic and hypotensive responses elicited by phenylbiguanide (PBG) administration. The baroreflex sensitivity (BRS) was evaluated by phenylephrine and sodium nitroprussite. Myocyte hypertrophy was determined by morphometric analysis of H&E stained slides. Biochemical data were analyzed, as well as micronucleus assay. MT improved BRS and increased testosterone values, but did not change estradiol in the OVX group. MT did not promote changes in mean arterial pressure, heart rate, BJR, serum concentrations of troponin I, weight and histopathology of the heart. MT was able to restore the BRS in OVX rats. The geno‐ and cytotoxic safety of the MT was demonstrated by the absence of an increase in the micronucleus (PCEMN) or change in the ratio between normochromatic erythrocytes and polychromatic erythrocytes (NCE/PCE). 相似文献
105.
Dynamic response of C‐type natriuretic peptide and its aminoterminal propeptide (NTproCNP) to growth hormone treatment in children with short stature
下载免费PDF全文
![点击此处可从《Clinical endocrinology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
106.
107.
Impact of oral clinical problems on oral health‐related quality of life in brazilian children: a hierarchical approach
下载免费PDF全文
![点击此处可从《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》网站下载免费的PDF全文](/ch/ext_images/free.gif)
João Gabriel Silva Souza Andréa Maria Eleutério De Barros Lima Martins Marise Fagundes Silveira Kimberly Marie Jones Maria Paula Maciel Rando Meirelles 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2017,27(1):66-78
108.
109.
110.