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101.

Statement of problem

Components have been introduced that allow the screw channel of an implant crown to be angled lingually and the screws to be tightened in a non-axial direction to the implant. Information is lacking as to how the removal torque value (RTV) and force to failure (FTF) of these components compare with those of conventional screws.

Purpose

The purpose of this in vitro study was to evaluate and compare the RTV and FTF values of cyclically loaded implant-supported restorations. Specifically, values for conventional axially tightened gold screws were compared with those for non-axially tightened screws aligned at 3 different angulations.

Material and methods

A total of 28 external hexagon implants were embedded in acrylic resin and divided into 4 groups. Simulated restorations were fabricated on abutments capable of different screw channel angulations. Dynamic abutments (DA) were waxed at different angulations and then cast. Simulated restorations were placed on the implants and tightened: group 0GS: 0-degree angulation gold screw tightened to 35 Ncm (control group); group 0DAS, 0-degree angulation with dynamic abutment (DAS) screw; group 20DAS: 20-degree angulation with DA screw; group 28DAS: 28-degree angulation with DAS screw. In groups 0DAS, 20DAS, and 28DAS, the DAS screw was used and tightened to 25 Ncm. Screw removal torque values were recorded by using a digital torque gauge at baseline and, after reaching cyclic fatigue, by using a dual-axis mastication simulator for 1 200 000 cycles. The fracture strength (FS) of the implant restorations was tested under compression until failure by using a universal testing machine. Differences between baseline and removal torque (ΔRT) were calculated. Statistical analysis was performed by using 1-way ANOVA for ΔRT and FS separately (α=.05).

Results

ΔRT and FS values were not significantly different among the groups (P>.05). The screw fractured in 5 of 28 specimens (17.8%); the remaining specimens failed with fracture of the implant.

Conclusions

The removal torque and FS values of the angulated abutment screw were comparable to those of the gold screw. Angulation of the abutment had no significant influence on the screw removal torque values.  相似文献   
102.

Background

Cranioplasty is a surgical procedure used to treat a bone defect or deformity in the skull. To date, there is little consensus on the standard-of-care for graft materials used in such a procedure. Graft materials must have sufficient mechanical strength to protect the underlying brain as well as the ability to integrate and support new bone growth. Also, the ideal graft material should be individually customized to the contours of the defect to ensure a suitable aesthetic outcome for the patient.

Purpose

Customized 3D-printed scaffolds comprising of polycaprolactone-β-tricalcium phosphate (PCL-TCP) have been developed with mechanical properties suitable for cranioplasty. Osteostimulation of PCL-TCP was enhanced through the addition of a bone matrix-mimicking heparan sulphate glycosaminoglycan (HS3) with increased affinity for bone morphogenetic protein-2 (BMP-2). Efficacy of this PCL-TCP/HS3 combination device was assessed in a rat critical-sized calvarial defect model.

Method

Critical-sized defects (5 mm) were created in both parietal bones of 19 Sprague Dawley rats (Male, 450–550 g). Each cranial defect was randomly assigned to 1 of 4 treatment groups: (1) A control group consisting of PCL-TCP/Fibrin alone (n = 5); (2) PCL-TCP/Fibrin-HSft (30 μg) (n = 6) (HSft is the flow-through during HS3 isolation that has reduced affinity for BMP-2); (3) PCL-TCP/Fibrin-HS3 (5 μg) (n = 6); (4) PCL-TCP/Fibrin-HS3 (30 μg) (n = 6). Scaffold integration and bone formation was evaluated 12-weeks post implantation by μCT and histology.

Results

Treatment with PCL-TCP/Fibrin alone (control) resulted in 23.7% ± 1.55% (BV/TV) of the calvarial defect being filled with new bone, a result similar to treatment with PCL-TCP/Fibrin scaffolds containing either HSft or HS3 (5 μg). At increased amounts of HS3 (30 μg), enhanced bone formation was evident (BV/TV = 38.6% ± 9.38%), a result 1.6-fold higher than control. Further assessment by 2D μCT and histology confirmed the presence of enhanced bone formation and scaffold integration with surrounding host bone only when scaffolds contained sufficient bone matrix-mimicking HS3.

Conclusion

Enhancing the biomimicry of devices using a heparan sulphate with increased affinity to BMP-2 can serve to improve the performance of PCL-TCP scaffolds and provides a suitable treatment for cranioplasty.  相似文献   
103.

Background

The authors conducted a systematic review that addresses the following population, intervention, comparison, outcome question: “In adults requiring dental therapy with pulpally involved teeth, what is the comparative efficacy of buffered local anesthetics (LAs) compared with that of nonbuffered LAs in achieving anesthetic success?”

Types of Studies Reviewed

The authors searched MEDLINE, Scopus, Cochrane Library, ClinicalTrials.gov, World Health Organization International Trials Registry Platform, OpenGrey, Google Scholar Beta, and 2 textbooks to identify double-blinded randomized controlled trials in which researchers directly compared the efficacy of buffered and nonbuffered LAs in adult participants, as well as any associated side effects. Furthermore, they checked the reference lists of all included and excluded studies to identify any further trials. Weighted anesthesia success rates were estimated and compared by using a random-effects model.

Results

A total of 14,011 studies were initially identified from the search; 5 double-blinded randomized clinical trials met inclusion criteria. Buffered LAs were more likely to achieve successful anesthesia than nonbuffered LAs (odds ratio, 2.29; 95% confidence interval, 1.11 to 4.71; P = .0232; I2 = 66%).

Conclusions and Practical Implications

This investigation revealed that buffered LAs are more effective than nonbuffered LAs when used for mandibular or maxillary anesthesia in pulpally involved teeth. Buffering of LAs has 2.29 times greater likelihood of achieving successful anesthesia.  相似文献   
104.
Affinity purified antibodies to plasma fibronectin were used to localize fibronectin in the connective tissues of inflamed and noninflamed beagle gingiva. In noninfiltrated gingival connective tissue, fibronectin was demonstrated in the basement membrane beneath gingival epithelium and around blood vessels as a uniform and intensely stained band about 3 to 10 micron thick. Fibronectin was also distributed throughout the connective tissue in association with collagen fibrils as a more diffuse, less intensely stained pattern. The inflamed gingiva included in this study was characterized by proliferation of epithelial pegs, heavy infiltration of plasma cells and loss of collagen within the subepithelial connective tissue. In these sites, fibronectin was present as an intensely stained band around blood vessels and at the crest of connective tissue papillae nearest the sulcular space. The fibronectin in the basement membrane beneath the epithelium appeared diminished and less uniformly distributed. A delicate network of fibronectin was present around plasma cells and the remaining collagen fibers.  相似文献   
105.
The aims of this study were to identify microorganisms on the surface of gutta-percha (GP) cones using a polymerase chain reaction (PCR) and to evaluate the sterilization effect of 5.25% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), and ChloraPrep on these bacteria. Alterations of the surface texture and physical properties of GP cone after chemical sterilization were compared. A total of 150 GP cones were randomly selected in endodontic clinics, and a PCR assay was performed to identify the contaminating microorganisms. After inoculation with the same microorganisms followed by drying for 1 day, the GP cones were immersed in the three chemical disinfectants. The sterilization effects were assessed by measuring the turbidity and through subculturing. The changes in surface texture were observed by scanning electron microscopy, and Instron 5500 (Instron Corp, Canton, MA) was used to measure the tensile strength and elongation rate of the GP cones after chemical sterilization. Statistical analysis was performed. Results indicate that 19.4% of GP cones from the clinic were contaminated, and all the species belonged to the genus Staphylococcus. Three chemical disinfectants were all effective in the rapid disinfection of GP cones against Staphylococcus spp, and 1-minute immersion of the GP cones was adequate for disinfection. Microphotographs of the NaOCl-soaked cone showed a cluster of cuboidal crystals. The tensile strength between the NaOCl- and CHX-soaked groups was significantly different (p<0.05), but there was no significant difference between the NaOCl- and ChloraPrep-soaked groups (p>0.05). All disinfectants significantly increased the elongation rate of the GP cones compared with fresh GP cones (p<0.05), especially in the ChloraPrep (Medi-flex, Leawood, KS). These results show that the three chemical disinfectants are effective agents for the rapid sterilization of GP cones. However, further research will be needed to determine the clinical relevance of the changes in physical properties.  相似文献   
106.
The aim of this study was to elucidate the precise anatomy of the zygomaticomandibularis muscle through cadaveric dissection and magnetic resonance imaging (MRI). Five fresh human cadavers and 10 fixed cadavers were dissected. Nine preserved human cadavers were used for the MRI study. Four volunteers took MRIs of their head as well. Zygomaticomandibularis muscle was found in all the cadaveric specimens. It is a fan shaped muscle. The length of the muscle is 25.1 +/- 4.6 mm, and the width at the zygomatic arch is 16.6 +/- 4.2 mm. The thickness is approximately 4.8 +/- 1.9 mm. It originates from the deep layer of the deep temporal fascia approximately 1 cm above the zygomatic arch and is inserted into the superior border and outer surface of the mandible between the coronoid process and mandibular notch. The deepest layer of the masseter muscle covers the lateral surface of zygomaticomandibularis. We believe that this muscle functions as coordinator of the temporalis and masseter in mammals with strong masticatory power but is a degraded or rudimentary muscle in humans.  相似文献   
107.
A histomorphogenic analysis of bone grafts augmented with adult stem cells   总被引:1,自引:0,他引:1  
PURPOSE: To evaluate the influence of bone marrow aspirate added to xenograft or alloplast graft matrix scaffold to produce bone. MATERIALS: A maximum of 4 cc bone marrow was aspirated from the anterior iliac crest of 5 patients to saturate the matrix scaffold prior to bone graft. Seven graft sites evaluated included sinus lift augmentation, particulate onlay graft of the maxilla via a tunneling procedure, and particulate onlay graft of the maxilla stabilized with titanium mesh. The xenograft scaffold was either PepGen Putty (DENTSPLY Friadent CeraMed, Lakewood, CO) or C-Graft resorbable algae material (Clinician's Preference, Golden, CO). The alloplast scaffold was beta-tricalcium phosphate (either Curasan AG, Kleinostheim, Germany, or Vitoss; Malvern, PA). RESULTS: Graft sites healed for 4-7 months. Core specimens of graft sites were taken with trephine drills, and submitted for standard histologic and histomorphogenic analysis. The percentage of graft material converted into bone, percentage of vital graft matrix, percentage of unresorbed matrix, and percentage of remaining interstitial tissue were measured. After a 4-month healing of sinus-lift augmentation with C-Graft, the biopsy showed 31% bone that was 100% vital. Unresorbed graft material was 26%, and remaining interstitial material constituted 43%. Using pure phase beta-tricalcium phosphate, a 4-month core biopsy showed 40% bone that was 100% vital. Residual graft was 3% and interstitial material 57%. A sinus grafted with PepGen P-15 (DENTSPLY Friadent CeraMed) was found to be 14% bone, with 100% of that bone vital. The non-bone within the core was 36%. After a 4 1/2-month healing of bilateral sinus grafts using a nonpure phase beta-tricalcium phosphate, the percentage of the biopsy that was bone was 23% on the right side and 16% on the left side. Vital bone was 89% (right side) and 86% (left side). The core taken after 4 months of healing from the anterior maxilla particulate onlay graft with PepGen P-15 showed 32% bone, with 100% found to be vital. Non-bone within the core was 15%, and 53% was interstitial material. After 7 months of healing, a biopsy core from the maxillary ridge augmented with C-Graft was 45% newly formed bone, with 100% of the bone vital. There was no residual graft material present. DISCUSSION: Bone regeneration by cell-based strategies depends upon an understanding of the biology and potential of adult stem cells as a method of regenerating bone. CONCLUSIONS: Bone marrow aspirate containing adult stem cells when mixed with bioengineered graft materials provide a scaffold to support the proliferation, differentiation, and maturation of the stem cells, as well as facilitating angiogenesis. This article presents histological evidence that stem cells aspirated from bone marrow and transplanted onto biocompatible scaffolds can successfully regenerate bone. This new standard for bone grafting may emerge as an alternative to autogenous bone grafts.  相似文献   
108.

Introduction

The aim of this study was to compare the cyclic fatigue, torsional resistance, and bending stiffness of single-file glide path preparation nickel-titanium instruments.

Methods

ProGlider (#16/progressive taper; Dentsply Sirona, Ballaigues, Switzerland), One G (#14/.03; Micro-Mega, Besancon, France), and EdgeGlidePath (#16/progressive taper; Edge Endo, Albuquerque, NM) were tested. For the bending stiffness test, the instrument was bent to a 45° angle along the main axis while 3 mm of the tip was secured. Cyclic fatigue resistance was measured during pecking movement, whereas the file was rotated within a reproducible simulated canal with a 3-mm radius and a 90° angle of curvature. The ultimate torsional strength and toughness were evaluated using a custom device. While tightly holding the end of the file at 3 mm, a rotational load of 2 rpm speed was applied until fracture. The results were analyzed using 1-way analysis of variance and Tukey post hoc comparison. A microscopic inspection was performed on the surface of a separate instrument using a scanning electron microscope.

Results

EdgeGlidePath showed superior cyclic fatigue resistance compared with the other systems. One G showed higher maximum torsional strength than the others. One G showed the largest distortion angle and the highest toughness followed by EdgeGlidePath and ProGlider (P < .05). One G also showed larger bending stiffness than the others, whereas EdgeGlidePath showed a larger residual angle than the others (P < .05).

Conclusions

Conventional wire showed higher toughness and torsional resistance than M-Wire and heat-treated nickel-titanium instruments. However, heat-treated wire showed higher cyclic resistance than conventional wire and M-Wire.  相似文献   
109.
OBJECTIVES: Miniscrews and miniplates are increasingly being used for absolute anchorage during orthodontic treatment. However, potential problems of damaging adjacent roots and their consequences during mini-implant placement in the alveolar process have not been clearly described. MATERIALS AND METHODS: Animal experiments were used to evaluate the stability of miniscrews placed with intentional root contact. The root repair was evaluated after screw removal. Seventy-two miniscrews were surgically placed in the mandibular alveolar bone of six adult mongrel dogs with metabolic bone labeling at 3-week intervals. Miniscrews of the experimental group were placed so that they contacted the root of the adjacent teeth, were retained for different time durations, and were then removed. The insertion torque, clinical measurements, removal torque, and histological findings were analyzed. RESULTS: (1) miniscrews contacting the roots showed a significantly higher insertion torque than those without contact; (2) there was a significant difference in the removal torque measurements based on the mobility of miniscrews and the state of root contact; and (3) miniscrews contacting the root were at greater risk of failure. CONCLUSIONS: During placement of miniscrews in the aveolar process, increased failure rates were noticed among those contacting adjacent roots. Failed miniscrews appeared to be surrounded with a greater volume of soft tissue. When more inflammation was present, the adjacent roots seemed to experience more resorption. Nevertheless, the created lesion was repaired with a narrow zone of mineralized tissue deposited on the root surface, which was likely cellular cementum, and was mainly filled with alveolar bone, with the periodontal ligament space being maintained.  相似文献   
110.
You SY  Kim HC  Bae KS  Baek SH  Kum KY  Lee W 《Journal of endodontics》2011,37(9):1296-1300

Introduction

Recently, root canal shaping with reciprocating motion has been postulated to reduce the possibility of unexpected file fractures. However, there has been little information on the shaping capability of this reciprocating motion preparation technique. Therefore, the purpose of this study was to evaluate the shaping ability of reciprocating motion when compared with continuous rotation motion in curved root canals.

Methods

The mesiobuccal and distobuccal canals of 20 extracted maxillary molars with curvatures of 20-45 degrees were instrumented with a series of ProTaper rotary files. The canals in the continuous rotation motion (CM) group (n = 20) were prepared by using continuous rotation with pecking motion, whereas the canals in the reciprocating motion (RM) group (n = 20) were prepared with reciprocating motion (clockwise 140 degrees and counterclockwise 45 degrees). Basic geometric parameters such as curvature, root canal volume, surface area, and structure model index (SMI) before and after canal shaping were evaluated by using micro-computed tomography. The degrees and directions of transportation were also measured, and statistical analysis was carried out with one-way analysis of variance and Tukey post hoc tests.

Results

There were no significant differences between the 2 groups in canal curvature, volume, surface area, and SMI categories measured before preparation (P > .05). Changes in curvature, root canal volume, surface area, and SMI were not affected by the instrumentation technique used (P > .05). There were no significant differences in the degrees and directions of transportation between CM and RM groups (P > .05).

Conclusions

The application of reciprocating motion during instrumentation did not result in increased apical transportation when compared with continuous rotation motion, even in the apical part of curved canals. Reciprocating motion might be an attractive alternative method to prevent procedural errors during root canal shaping.  相似文献   
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