全文获取类型
收费全文 | 454篇 |
免费 | 19篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 36篇 |
妇产科学 | 3篇 |
基础医学 | 17篇 |
口腔科学 | 9篇 |
临床医学 | 38篇 |
内科学 | 61篇 |
皮肤病学 | 8篇 |
神经病学 | 6篇 |
特种医学 | 120篇 |
外科学 | 45篇 |
综合类 | 30篇 |
预防医学 | 28篇 |
眼科学 | 27篇 |
药学 | 33篇 |
肿瘤学 | 31篇 |
出版年
2023年 | 2篇 |
2020年 | 1篇 |
2019年 | 3篇 |
2018年 | 8篇 |
2017年 | 2篇 |
2016年 | 5篇 |
2015年 | 10篇 |
2014年 | 8篇 |
2013年 | 12篇 |
2012年 | 5篇 |
2011年 | 7篇 |
2010年 | 11篇 |
2009年 | 13篇 |
2008年 | 11篇 |
2007年 | 22篇 |
2006年 | 33篇 |
2005年 | 17篇 |
2004年 | 17篇 |
2003年 | 7篇 |
2002年 | 10篇 |
2001年 | 21篇 |
2000年 | 7篇 |
1999年 | 10篇 |
1998年 | 33篇 |
1997年 | 21篇 |
1996年 | 26篇 |
1995年 | 22篇 |
1994年 | 19篇 |
1993年 | 22篇 |
1992年 | 6篇 |
1991年 | 4篇 |
1990年 | 9篇 |
1989年 | 5篇 |
1988年 | 7篇 |
1987年 | 4篇 |
1986年 | 11篇 |
1985年 | 8篇 |
1984年 | 7篇 |
1983年 | 6篇 |
1982年 | 7篇 |
1981年 | 7篇 |
1980年 | 13篇 |
1979年 | 3篇 |
1978年 | 4篇 |
1977年 | 4篇 |
1976年 | 4篇 |
1975年 | 1篇 |
排序方式: 共有495条查询结果,搜索用时 500 毫秒
81.
82.
Frans van Workum Laura Fransen Misha DP Luyer Camiel Rosman 《World journal of gastroenterology : WJG》2018,24(44):4974-4978
Surgical innovation and pioneering are important for improving patient outcome, but can be associated with learning curves. Although learning curves in surgery are a recognized problem, the impact of surgical learning curves is increasing, due to increasing complexity of innovative surgical procedures, the rapid rate at which new interventions are implemented and a decrease in relative effectiveness of new interventions compared to old interventions. For minimally invasive esophagectomy(MIE), there is now robust evidence that implementation can lead to significant learning associated morbidity(morbidity during a learning curve, that could have been avoided if patients were operated by surgeons that have completed the learning curve). This article provides an overview of the evidence of the impact of learning curves after implementation of MIE. In addition, caveats for implementation and available evidence regarding factors that are important for safe implementation and safe pioneering of MIE are discussed. 相似文献
83.
84.
DP Harji S Rastall C Catchpole R Bright-Thomas S Thrush 《Annals of the Royal College of Surgeons of England》2010,92(3):e20-e22
Breast infection and breast sepsis secondary to Pseudomonas aeruginosa is uncommon. We report two cases of pseudomonal breast infection leading to septic shock and abscess formation in women with non-responding breast infection. The management of breast infection is broad-spectrum antibiotics and ultrasound with aspiration of any collection. To treat breast infection effectively, the causative organism must be isolated to enable appropriate antibiotic therapy. 相似文献
85.
A A Pontual DP de Melo SM de Almeida FN Bóscolo F Haiter Neto 《Dento maxillo facial radiology》2010,39(7):431-436
Objectives
The aims of this study were (1) to compare the accuracy of the detection of approximal enamel caries lesions using three intraoral storage phosphor plate digital systems and one conventional film-based radiographic system; and (2) to determine whether there is a correlation between the histological and radiographic measurements of enamel caries.Methods
160 approximal surfaces were radiographed under standardized conditions using three storage phosphor stimulable systems (DenOptix and Digora FMX with white and blue plates), and one film system (Insight film). 17 observers scored the images for the presence and depth of caries using a 4-point scale. The presence of caries was validated histologically (gold standard). Two-way analysis of variance was used to test the differences in sensitivity, specificity and overall accuracy (TP + TN). The data from the radiographic and histological measurements were statistically analysed by Spearman’s rank correlation coefficient.Results
Two-way analysis of variance and the post hoc t-test demonstrated that Digora (white plate) had higher specificity and overall accuracy values than DenOptix (P = 0.021); there was no statistically significant difference among the other imaging modalities (P > 0.05). There was no significant correlation between the histological depth measurements and the radiographic measurements from Digora (blue plate) (P = 0.43), Digora (white plate) (P = 0.15), DenOptix (P = 0.17) and Insight film (P = 0.06).Conclusions
The results suggest that (1) the performance of the three storage phosphor image plate systems was similar to that of the Insight film for detection of approximal enamel caries, and (2) the increase in histological depth of enamel caries was not significantly correlated with radiographic measurements. 相似文献86.
Gordon C Wishart Elizabeth M Azzato David C Greenberg Jem Rashbass Olive Kearins Gill Lawrence Carlos Caldas Paul DP Pharoah 《Breast cancer research : BCR》2010,12(1):R1
Introduction
The aim of this study was to develop and validate a prognostication model to predict overall and breast cancer specific survival for women treated for early breast cancer in the UK. 相似文献87.
88.
Teus J Weijs Jelle P Ruurda Grard AP Nieuwenhuijzen Richard van Hillegersberg Misha DP Luyer 《World journal of gastroenterology : WJG》2013,19(39):6509-6514
Esophagectomy,the surgical removal of all or part of the esophagus,is a surgical procedure that is associated with high morbidity and mortality.Pulmonary complications are an especially important postoperative problem.Therefore,many perioperative strategies to prevent pulmonary complications after esophagectomy have been investigated and introduced in daily clinical practice.Here,we review these strategies,including improvement of patient performance and technical advances such as minimally invasive surgery that have been implemented in recent years.Furthermore,interventions such as methylprednisolone,neutrophil elastase inhibitor and epidural analgesia,which have been shown to reduce pulmonary complications,are discussed.Benefits of the commonly applied routine nasogastric decompression,delay of oral intake and prophylactic mechanical ventilation are unclear,and many of these strategies are also evaluated here.Finally,we will discuss recent insights and new developments aimed to improve pulmonary outcomes after esophagectomy. 相似文献
89.
Faulkner KA Redfern MS Rosano C Landsittel DP Studenski SA Cauley JA Zmuda JM Simonsick EM Kritchevsky SB Newman AB;Health ABC Study 《Gait & posture》2006,24(2):182-189
This study investigated how cognitive and walking performance are influenced when performed concurrently in older adults and what factors are associated with poorer dual-task responses. Using a dual-task study design, 217 subjects aged 74-85 years completed three information processing test conditions--(1) no test; (2) push-button simple reaction-time; and (3) visual-spatial decision reaction-time; and three walking test conditions--(1) seated; (2) walking over a 20m straight course; and (3) walking over 20m with a turn. Push-button and visual-spatial reaction-times increased approximately 21% and 6%, respectively, while walking compared to sitting (p<0.008). Reaction-time tests had a relatively weak impact on walking-time. Poorer dual-task walking-time responses correlated with slower walking velocity and weaker muscle strength (p< or =.062). Findings suggest that walking requires significant cognitive resources among older adults and slower-walking adults and weaker adults may require higher cognitive loading while walking. 相似文献
90.
目的 用重组日本血吸虫22kD表膜蛋白(rSj22)免疫水牛,检测特异性IgG抗体的应答水平,并观察抗血吸虫的保护效果。方法 用抗原(rSj22)加佐剂(Quil-A)肌肉注射免疫水牛,以1000条日本血吸虫尾蚴攻击感染,感染后55d剖杀,计算减虫和减卵率,用免疫印斑和ELISA方法测定抗体反应。结果 免疫组每头牛血清均能特异地识别Quil-A对照组相比,减虫率仅8.5%肝卵EPG减少12.3%,粪卵EPG减少26.8%,但均无统计学意义,结论 用rSj22kD抗原免疫水牛诱导的特异性IgG抗体不能发挥免疫保护作用。 相似文献