全文获取类型
收费全文 | 6046篇 |
免费 | 342篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 63篇 |
儿科学 | 164篇 |
妇产科学 | 93篇 |
基础医学 | 933篇 |
口腔科学 | 140篇 |
临床医学 | 394篇 |
内科学 | 1583篇 |
皮肤病学 | 122篇 |
神经病学 | 650篇 |
特种医学 | 110篇 |
外科学 | 584篇 |
综合类 | 33篇 |
一般理论 | 1篇 |
预防医学 | 204篇 |
眼科学 | 216篇 |
药学 | 575篇 |
中国医学 | 35篇 |
肿瘤学 | 509篇 |
出版年
2023年 | 49篇 |
2022年 | 68篇 |
2021年 | 149篇 |
2020年 | 63篇 |
2019年 | 115篇 |
2018年 | 136篇 |
2017年 | 91篇 |
2016年 | 128篇 |
2015年 | 133篇 |
2014年 | 162篇 |
2013年 | 197篇 |
2012年 | 335篇 |
2011年 | 385篇 |
2010年 | 215篇 |
2009年 | 183篇 |
2008年 | 345篇 |
2007年 | 392篇 |
2006年 | 351篇 |
2005年 | 382篇 |
2004年 | 341篇 |
2003年 | 334篇 |
2002年 | 331篇 |
2001年 | 97篇 |
2000年 | 120篇 |
1999年 | 116篇 |
1998年 | 56篇 |
1997年 | 50篇 |
1996年 | 46篇 |
1995年 | 34篇 |
1994年 | 49篇 |
1993年 | 32篇 |
1992年 | 105篇 |
1991年 | 74篇 |
1990年 | 83篇 |
1989年 | 75篇 |
1988年 | 62篇 |
1987年 | 73篇 |
1986年 | 68篇 |
1985年 | 50篇 |
1984年 | 38篇 |
1983年 | 35篇 |
1982年 | 35篇 |
1981年 | 23篇 |
1980年 | 15篇 |
1979年 | 25篇 |
1978年 | 16篇 |
1974年 | 14篇 |
1973年 | 19篇 |
1968年 | 13篇 |
1967年 | 13篇 |
排序方式: 共有6409条查询结果,搜索用时 31 毫秒
101.
Kawada T Yamazaki T Akiyama T Sato T Shishido T Yoshimura R Inagaki M Tatewaki T Sugimachi M Sunagawa K 《Journal of the autonomic nervous system》2000,78(2-3):94-98
Although several investigations have suggested cardiac epinephrine (Epi) release, local Epi release in the myocardial interstitium in vivo has not been measured. Using cardiac microdialysis in the rabbit, we measured dialysate Epi and norepinephrine (NE) concentrations as indices of myocardial interstitial Epi and NE levels, respectively. Exocytotic release induced by local administration of KCl (100 mM) through the dialysis probe increased Epi to 24.2 +/- 13.2 pg/ml from a control value of 3.2 +/- 3.6 pg/ml (P < 0.01, n = 6). Non-exocytotic release induced by the local administration of tyramine (10 microg/ml) also increased Epi to 34.6 +/- 15.3 pg/ml (p < 0.05 from control, n = 6). We conclude that Epi can be released via both exocytotic and non-exocytotic release mechanisms from the heart. 相似文献
102.
Kyoko Nishikawa 《Nihon Arukōru Yakubutsu Igakkai zasshi》2005,40(6):537-548
A research by questionnaire was conducted at three medical institutions, on basic attributes and psychosocial states of alcoholics' as first time inpatient and respective families. After a year of research, additional study was conducted in regard of abstinence, treatment continuation as outpatient, participation in self-help groups, and family's participation in family groups. Outcomes of researches' statistical analyses showed significant differences concerning medical institutions and basic attributes for the items: treatment histories of alcoholism, treatment or inpatient in other medical departments and alcoholic's family history,; but these differences were considered to be associated with varied courses of referrals. In relation to medical institutions with patients and family's psychosocial states, there were no significant differences on the outcomes of five scales. As for the correlation between medical institutions with a year's prognoses there were no significant differences concerning abstinence and treatment continuation as outpatient. In case of participation in self-help groups and family groups, the prognoses showed significant differences but these differences were considered to be related to varied treatments and different helping ways of medical institutions and varied conditions of local communities for mentioned helps. 相似文献
103.
Novel PSTPIP1 gene mutation in pyoderma gangrenosum,acne and suppurative hidradenitis syndrome
下载免费PDF全文
![点击此处可从《The Journal of dermatology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
104.
Masaya Kibe Satoshi Ibara Hidehito Inagaki Takema Kato Hiroki Kurahashi Toshiro Ikeda 《American journal of medical genetics. Part A》2018,176(5):1245-1248
Bohring–Opitz syndrome (BOS) is a rare disease with a number of characteristic features, including hypertelorism, prominent metopic suture, exophthalmos, cleft palate, abnormal posture, and developmental retardation. Here, we report a BOS patient presenting with lethal persistent pulmonary hypertension of the newborn (PPHN) and inspiratory respiratory failure. The female infant was treated with nitric oxide and vasodilator, which did not improve her condition. The inspiratory respiratory failure required management with deep sedation. She died on postnatal day 60 due to progressed heart failure. Whole exome sequencing revealed de novo mutation in the ASXL1 gene, c.1934dupG, p.Gly646TrpfsTer12. 相似文献
105.
Kyoko Kanno Masako Minami‐Hori Akemi Ishida‐Yamamoto Keiji Komura Kensuke Oikawa Naoyuki Miyokawa Hajime Iizuka 《The Journal of dermatology》2014,41(8):736-738
We report a 38‐year‐old male patient who presented with cutaneous lesions mimicking widespread discoid lupus erythematosus with high‐grade fever, arthralgia and lymphadenopathy. Additional lymph node and skin biopsies, however, revealed karyorrhectic debris without neutrophils and numerous CD68‐positive cells, a characteristic finding of Kikuchi's disease (KD). Comparing skin biopsies on different occasions, we could see different forms of histopathology. The histopathology of skin lesions of KD may vary during the clinical course, which may reflect the stage of the disease. 相似文献
106.
107.
Ana Dorcas de Melo Inagaki Cristina Gardonyi Carvalheiro Rosana Cipolotti Ricardo Queiroz Gurgel Dayse Alves Rocha Kariny Souza Pinheiro Raquel Melo Araújo Dorothy Ribeiro Resende Lima Jacques Leon Winandy Marisa Márcia Mussi‐Pinhata 《Tropical medicine & international health : TM & IH》2012,17(11):1349-1355
Objectives To estimate, by neonatal screening, the birth prevalence of congenital toxoplasmosis among live‐born infants in Sergipe state, Brazil, and to investigate the clinical features of affected infants. Methods Dried blood spot specimens obtained from 15 204 neonates were assayed for the presence of anti‐T. gondii IgM antibodies. Duplicate retesting was done in infants with positive and borderline results. Confirmatory testing in peripheral blood samples consisted of testing for anti‐T. gondii IgG and IgM in infants and mothers. Those with possible congenital toxoplasmosis were evaluated and followed up to a median age of 20 months. Congenital infection was confirmed in the presence of persisting anti‐T. gondii IgG antibodies beyond 12 months of age. All infants with confirmed infection were treated with pyrimethamine, sulfadiazine and folinic acid for 1 year. Results Fifty‐three infants had detectable IgM in dried blood spot specimens. Confirmatory testing was reactive in 39/50, of which, 38 completed follow‐up. Six of 15 204 newborns were diagnosed with congenital toxoplasmosis, resulting in an estimated birth prevalence of four per 10 000 [CI 95% 1.4–8.0]. Four infants (67%) showed signs of congenital toxoplasmosis in their first year of life; three (75%) had retinochoroidal scars, and one had cerebral calcifications. Two infants remained asymptomatic until 20 months of age. Conclusions The birth prevalence of congenital toxoplasmosis is high in the Brazilian state of Sergipe, with most of the infants showing ocular lesions. Preventive measures are strongly warranted. 相似文献
108.
109.
Osteogenic differentiation in dedifferentiated liposarcoma: a study of 36 cases in comparison to the cases without ossification
下载免费PDF全文
![点击此处可从《Histopathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
110.
Kato Akiko Inagaki Koji Utsumi Michiya Kato Kazuo Honda Masaki 《Odontology / the Society of the Nippon Dental University》2021,109(1):193-200
Odontology - The aim of this study was to investigate root canal configurations in maxillary first and second molars from a Japanese population, as well as the relationship between the root canal... 相似文献