Biocompatibility and strength properties of nitinol shape memory alloy suture in rabbit tendon

Nitinol (NiTi) is a promising new tendon suture material with good strength, easy handling and good super-elastic properties. NiTi sutures were implanted for biocompatibility testing into the right medial gastrocnemius tendon in 15 rabbits for 2, 6 and 12 weeks. Additional sutures were implanted in subcutaneous tissue for strength measurements in order to determine the effect of implantation on strength properties of NiTi suture material. Braided polyester sutures (Ethibond) of approximately the same diameter were used as control. Encapsulating membrane formation around the sutures was minimal in the case of both materials. The breaking load of NiTi was significantly greater compared to braided polyester. Implantation did not affect the strength properties of either material.     

Sports career-related musculoskeletal injuries: long-term health effects on former athletes

Despite the high absolute number of sports injuries, most are not usually severe and consequent permanent disabilities are uncommon. Based on epidemiological data, former athletes have more degenerative changes in their joints and spine compared with control populations; however, at old age, their good muscle function related to high physical activity level seems to compensate for the effects of degenerative changes on function. There are former athletes who report disabilities due to different types of musculoskeletal injuries from sports careers. This article attempts to characterise this problem; however, more detailed studies are needed, particularly because the training regimens of the athletes seem to be increasingly demanding.     

Language context and phonetic change detection

Event-related brain potentials (ERP) were recorded to two spoken words, /paeti/ and /peti/. The vowel difference between the two words results in a semantical difference in Finnish, but not in Hungarian, in which /ae/ and /e/ are perceived as allophones of the same vowel /epsilon/. As a consequence, native Hungarian speakers, who had not studied Finnish before being tested, could not categorize the two word stimuli. In the main experiment, native Hungarian speakers, who fluently spoke Finnish, were presented with two oddball sequences in which /paeti/ was the frequent standard stimulus, /peti/ the infrequent deviant. In addition, very rare target words were also included. In one condition, the targets were Hungarian words, whereas in the other, they were Finnish words. The participants' sense of being in two different language environments was further encouraged by having separate experimenters conducting the two conditions, one speaking with the subjects only in Hungarian, the other only in Finnish. Language context had no effect on the mismatch negativity ERP component elicited by the deviant word stimuli. This result suggests that language context does not affect the pre-attentive detection of auditory deviance.     

Unrecognized dementia in elderly patients admitted to hospital with psychiatric symptoms

In this study, we hypothesized that elderly patients with first admission to a psychiatric hospital commonly suffer from dementia but did not have such a diagnosis on admission. Over a period of 5 years, we surveyed all medical journals from patients treated for the first time at the Department of Psychogeriatrics. By selecting all inpatients treated at the only regional psychiatric hospital within a defined geographic area, the selected patients became representative of this geographic area. After a diagnostic work-up at the hospital, 72 of 239 patients satisfied clinical criteria of dementia. Of these patients, 7 had Alzheimer's disease and 7 had evidence of vascular dementia. We identified 51 of 72 patients (71%) with an endpoint diagnosis of dementia made at the hospital without any clinical information suggesting dementia at the time of hospitalization. Nonspecific psychosis (35%), depression (15%), and behavioral disturbances (8%) represented the most common diagnoses proposed by the referring doctor. In conclusion, dementia may be a difficult diagnosis in elderly patients with psychiatric symptoms. This study reminds clinicians that dementia should be considered in these patients.     

Personality and mood of former elite male athletes--a descriptive study

The purpose of this study was to describe the personality and mood of former athletes in middle and old age. The subjects were male athletes who represented Finland from 1920 to 1965 and male referents who were classified as healthy at 20 years of age. The athletes were classified into a total of five athlete groups (endurance, power/combat, power/individual, team, shooting) and one reference group. Four personality scales (extroversion, neuroticism, life satisfaction, and hostility) were used in a baseline questionnaire in 1985 (athletes N = 1040, referents N = 777). Anxiety and depression were assessed in a follow-up in 1995 (athletes N = 758, referents N = 578) with a shortened version of the BSI-53 symptom inventory. According to ANCOVA there were group differences in extroversion, neuroticism, and life satisfaction but not in hostility. Athletes who had participated in power/combat sports and team sports were more extroverted than referents. Endurance sport and shooting sport athletes had lower neuroticism scores than the referents. Endurance, power/combat, team and shooting sport athletes were more satisfied with their lives than were the referents. Discriminant analysis mainly supported these findings. Differences regarding depression were also statistically significant between the groups as referents were more depressed than endurance sport and team sport athletes. No group differences in anxiety were found. The subjects described in this study are unique in number of respects. Bearing in mind the limitations of the study subjects, it is concluded that former athletes differ from nonathletes in some personality characteristics and depression.     

POSTNATAL DEVELOPMENT OF RENAL FUNCTION IN PRE-TERM AND FULL-TERM INFANTS

ABSTRACT. Aperia, A., Broberger, B., Klinder, G., Herin, P. and Zetterström, R. (Department of Paediatrics, Karolinska Institute, St. Göran's Children's Hospital, Stockholm and Huddinge Hospital, Huddinge, Sweden). Postnatal deveopment of renal function in preterm and full-term infants. Acta Paediatr Scand, 70:183, 1981. –This study has been designed to examine the effect of gestational age (GA) on the postnatal development of renal function and has been performed in pre-term (PT) infants (GA=30–34 weeks) and in full-term (FT) infants (GA=39–41 weeks). Postnatal age has ranged from 1–35 days. From 8 hour urine samples collected after spontaneous voiding and a capillary blood sample, determinations have been made of the clearance of creatinine (C_Cr), the fractional excretion of β₂-microglobulin (FE_β2) and the fractional excretion of sodium (FE_Na). In some infants receiving fluid parenterally, simultaneous determinations were made of the clearance of creatinine and inulin. As judged from this study, C_Cr is a reliable indicator of the glomerular filtration rate (GFR). GFR was almost the same in newborn PT and FT, but from 0.3–1 week of age GFR increased significantly more rapidly in FT than in PT. From 1–5 weeks of age GFR increased at approximately the same rate in PT and FT infants. The absolute value for GFR in 3–5 weeks old infants was lower in PT than in FT. FE_β2 was higher in PT than in FT infants during the entire first month of life and FE_Na was higher in PT than in FT infants during the first week of life, suggesting a glomerular tubular imbalance at least at the level of the proximal tubule in PT infants. It is concluded that different stages of maturation will alter the preconditions for the renal adaptation to extrauterine life during at least the first month of life. Therefore special attention must be paid to the limited renal function in PT during their entire first month of life.     

Self-Reported Restrictive Eating,Eating Disorders,Menstrual Dysfunction,and Injuries in Athletes Competing at Different Levels and Sports

The purpose of this study was to investigate the prevalence of self-reported restrictive eating, current or past eating disorder, and menstrual dysfunction and their relationships with injuries. Furthermore, we aimed to compare these prevalences and associations between younger (aged 15–24) and older (aged 25–45) athletes, between elite and non-elite athletes, and between athletes competing in lean and non-lean sports. Data were collected using a web-based questionnaire. Participants were 846 female athletes representing 67 different sports. Results showed that 25%, 18%, and 32% of the athletes reported restrictive eating, eating disorders, and menstrual dysfunction, respectively. Higher rates of lean sport athletes compared with non-lean sport athletes reported these symptoms, while no differences were found between elite and non-elite athletes. Younger athletes reported higher rates of menstrual dysfunction and lower lifetime prevalence of eating disorders. Both restrictive eating (OR 1.41, 95% CI 1.02–1.94) and eating disorders (OR 1.89, 95% CI 1.31–2.73) were associated with injuries, while menstrual dysfunction was associated with more missed participation days compared with a regular menstrual cycle (OR 1.79, 95% CI 1.05–3.07). Our findings indicate that eating disorder symptoms and menstrual dysfunction are common problems in athletes that should be managed properly as they are linked to injuries and missed training/competition days.     

Speed and quality in Coronary Artery Bypass Graft (CABG) surgery: is there a connection?

In this paper we study the connection between coronary artery bypass graft (CABG) operation time and quality. Our quality metric was the improvement in health related quality of life (HRQoL) survey score in a sample of 432 patients admitted to Kuopio University Hospital. Patients were interviewed with a structured questionnaire a day before the procedure and the follow-up questionnaires were mailed 6 and 12 months after the surgery. However, the HRQoL metric used did not have high retest reliability. Subsequently, we did not find any connection between CAGB operation times and HRQoL. Likewise, we did not find the speed of the surgeon to have any connection to HRQoL improvement.