全文获取类型
收费全文 | 52711篇 |
免费 | 6252篇 |
国内免费 | 93篇 |
专业分类
耳鼻咽喉 | 700篇 |
儿科学 | 1600篇 |
妇产科学 | 1391篇 |
基础医学 | 7723篇 |
口腔科学 | 1156篇 |
临床医学 | 7576篇 |
内科学 | 10501篇 |
皮肤病学 | 686篇 |
神经病学 | 4201篇 |
特种医学 | 1614篇 |
外国民族医学 | 1篇 |
外科学 | 7169篇 |
综合类 | 1022篇 |
一般理论 | 31篇 |
预防医学 | 5592篇 |
眼科学 | 794篇 |
药学 | 4076篇 |
中国医学 | 76篇 |
肿瘤学 | 3147篇 |
出版年
2022年 | 414篇 |
2021年 | 793篇 |
2020年 | 668篇 |
2019年 | 843篇 |
2018年 | 1110篇 |
2017年 | 860篇 |
2016年 | 1009篇 |
2015年 | 1053篇 |
2014年 | 1389篇 |
2013年 | 2013篇 |
2012年 | 2560篇 |
2011年 | 2581篇 |
2010年 | 1539篇 |
2009年 | 1471篇 |
2008年 | 2236篇 |
2007年 | 2333篇 |
2006年 | 2316篇 |
2005年 | 2294篇 |
2004年 | 2196篇 |
2003年 | 2092篇 |
2002年 | 2049篇 |
2001年 | 1712篇 |
2000年 | 1735篇 |
1999年 | 1536篇 |
1998年 | 709篇 |
1997年 | 591篇 |
1996年 | 496篇 |
1995年 | 533篇 |
1994年 | 496篇 |
1993年 | 462篇 |
1992年 | 1184篇 |
1991年 | 1141篇 |
1990年 | 1108篇 |
1989年 | 1014篇 |
1988年 | 934篇 |
1987年 | 966篇 |
1986年 | 916篇 |
1985年 | 939篇 |
1984年 | 747篇 |
1983年 | 650篇 |
1982年 | 452篇 |
1981年 | 383篇 |
1980年 | 392篇 |
1979年 | 614篇 |
1978年 | 469篇 |
1977年 | 382篇 |
1976年 | 407篇 |
1974年 | 405篇 |
1973年 | 365篇 |
1972年 | 364篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
11.
T. Wu L. G. Trahair M. J. Bound C. F. Deacon M. Horowitz C. K. Rayner K. L. Jones 《Diabetic medicine》2015,32(5):595-600
12.
David M. Presby Michael C. Rudolph Vanessa D. Sherk Matthew R. Jackman Rebecca M. Foright Kenneth L. Jones Julie A. Houck Ginger C. Johnson Janine A. Higgins P. Darrell Neufer Robert H. Eckel Paul S. MacLean 《Diabetes》2021,70(4):867
Moderate weight loss improves numerous risk factors for cardiometabolic disease; however, long-term weight loss maintenance (WLM) is often thwarted by metabolic adaptations that suppress energy expenditure and facilitate weight regain. Skeletal muscle has a prominent role in energy homeostasis; therefore, we investigated the effect of WLM and weight regain on skeletal muscle in rodents. In skeletal muscle of obesity-prone rats, WLM reduced fat oxidative capacity and downregulated genes involved in fat metabolism. Interestingly, even after weight was regained, genes involved in fat metabolism were also reduced. We then subjected mice with skeletal muscle lipoprotein lipase overexpression (mCK-hLPL), which augments fat metabolism, to WLM and weight regain and found that mCK-hLPL attenuates weight regain by potentiating energy expenditure. Irrespective of genotype, weight regain suppressed dietary fat oxidation and downregulated genes involved in fat metabolism in skeletal muscle. However, mCK-hLPL mice oxidized more fat throughout weight regain and had greater expression of genes involved in fat metabolism and lower expression of genes involved in carbohydrate metabolism during WLM and regain. In summary, these results suggest that skeletal muscle fat oxidation is reduced during WLM and regain, and therapies that improve skeletal muscle fat metabolism may attenuate rapid weight regain. 相似文献
13.
14.
Gastro-oesophageal reflux disease (GORD) is symptomatic reflux of gastric contents into the oesophagus. Factors predisposing to GORD are loss of the physiological antireflux barrier and anatomic abnormalities of the oesophagus or diaphragm. Conservative measures and medical management results in resolution of symptoms in a majority of children. Surgery is indicated in the event of failure of medical management or severe complications. Surgical procedures include open or laparoscopic fundoplication in children with normal neurology; fundoplication with or without vagotomy and pyloroplasty; surgical feeding jejunostomy and oesophago-gastric dissociation in the severely neurologically impaired children. 相似文献
15.
16.
17.
18.
Worsening pneumonitis due to a pharmacokinetic drug–drug interaction between everolimus and voriconazole in a renal transplant patient 下载免费PDF全文
19.
ABSTRACTBoth international tourism and migration of people with low English proficiency (LEP) to Australia are increasing. Thus, health-care practitioners (HPs) increasingly use interpreters to communicate with patients with LEP. Although qualified interpreters are the most suggested and policy-endorsed mechanism for communicating with patients with LEP, family members (FMIs) are also used as interpreters. This study investigated (a) when do health professionals consider it appropriate to use FMIs and (b) what characteristics of family members health professionals believe make them suitable to act as FMIs. As part of a larger project examining the decision-making processes of HPs regarding interpreter use, 69 HPs from neonatal and pediatric departments in one hospital in Queensland Australia were interviewed. Results indicated HPs thought the appropriateness of using FMIs depended on the type of information, such that it was either completely acceptable (e.g., explaining some basic or non-medical information) or completely unacceptable (e.g., confidential information or consent). However, in an emergency, when no other options were available, FMIs were used. The characteristics of suitable FMIs included age, level of English proficiency and medical understanding, and the relationship between patient and FMI. Results were to some extent consistent with Queensland government policies but there were notable differences, including using children and regarding FMIs as first preference. Improving HP’s knowledge of policies may increase their confidence in their practice and appropriate use of FMIs, thereby improving their care delivery to patients and families with LEP. 相似文献
20.