全文获取类型
收费全文 | 28774篇 |
免费 | 1219篇 |
国内免费 | 134篇 |
专业分类
耳鼻咽喉 | 304篇 |
儿科学 | 495篇 |
妇产科学 | 315篇 |
基础医学 | 3860篇 |
口腔科学 | 638篇 |
临床医学 | 1811篇 |
内科学 | 7201篇 |
皮肤病学 | 347篇 |
神经病学 | 2456篇 |
特种医学 | 1091篇 |
外科学 | 4517篇 |
综合类 | 160篇 |
一般理论 | 2篇 |
预防医学 | 819篇 |
眼科学 | 794篇 |
药学 | 2279篇 |
中国医学 | 147篇 |
肿瘤学 | 2891篇 |
出版年
2023年 | 109篇 |
2022年 | 208篇 |
2021年 | 394篇 |
2020年 | 206篇 |
2019年 | 309篇 |
2018年 | 378篇 |
2017年 | 296篇 |
2016年 | 406篇 |
2015年 | 453篇 |
2014年 | 581篇 |
2013年 | 786篇 |
2012年 | 1341篇 |
2011年 | 1486篇 |
2010年 | 800篇 |
2009年 | 681篇 |
2008年 | 1327篇 |
2007年 | 1523篇 |
2006年 | 1500篇 |
2005年 | 1614篇 |
2004年 | 1564篇 |
2003年 | 1492篇 |
2002年 | 1546篇 |
2001年 | 826篇 |
2000年 | 837篇 |
1999年 | 800篇 |
1998年 | 453篇 |
1997年 | 387篇 |
1996年 | 372篇 |
1995年 | 308篇 |
1994年 | 317篇 |
1993年 | 256篇 |
1992年 | 601篇 |
1991年 | 611篇 |
1990年 | 562篇 |
1989年 | 522篇 |
1988年 | 425篇 |
1987年 | 387篇 |
1986年 | 405篇 |
1985年 | 379篇 |
1984年 | 289篇 |
1983年 | 237篇 |
1982年 | 158篇 |
1981年 | 140篇 |
1980年 | 161篇 |
1979年 | 208篇 |
1978年 | 151篇 |
1977年 | 138篇 |
1975年 | 104篇 |
1974年 | 117篇 |
1972年 | 114篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
31.
32.
33.
Yuji Maruyama Shigeo Yamauchi Hidetsugu Ogasawara Hajime Imura Masami Ochi Kazuo Shimizu 《Annals of thoracic and cardiovascular surgery》2006,12(1):60-62
Surgical treatment for subacute pulmonary arterial thromboembolism has previously been considered to be inappropriate. We undertook a pulmonary arterial thrombectomy and removal of a floating right heart thrombus in a patient who had been symptomatic for over a month. The pulmonary arterial pressure, which had been equal to the systemic pressure preoperatively, decreased gradually and almost normalized one month postoperatively. Pulmonary perfusion scintigraphy revealed a dramatic improvement and the patient returned to normal life activities. 相似文献
34.
Use of Glycopeptidolipid Core Antigen for Serodiagnosis of Mycobacterium avium Complex Pulmonary Disease in Immunocompetent Patients
下载免费PDF全文
![点击此处可从《Clinical and Vaccine Immunology : CVI》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Seigo Kitada Ryoji Maekura Naomi Toyoshima Takashi Naka Nagatoshi Fujiwara Masami Kobayashi Ikuya Yano Masami Ito Kazuo Kobayashi 《Clinical and Vaccine Immunology : CVI》2005,12(1):44-51
We report the development of a serodiagnostic method for Mycobacterium avium complex (MAC) disease with an enzyme immunoassay (EIA) with the MAC-specific glycopeptidolipid (GPL) core as the antigen. In this study, we confirmed by EIA that the GPL core antibody was in the sera of immunocompetent patients with MAC disease. The EIA for quantifying the GPL core antibody was evaluated as a clinical tool for serodiagnosis of pulmonary MAC disease. A significant increase in GPL core antibodies (immunoglobulins G, A, and M) was detected in sera of patients with MAC pulmonary diseases when they were compared to patients who were colonized with MAC, patients with Mycobacterium kansasii disease or tuberculosis, and healthy subjects. The sensitivities and specificities of the GPL core-based EIA for diagnosis of MAC pulmonary disease were 72.6% and 92.2%, respectively, for IgG, 92.5% and 95.1%, respectively, for IgA, and 78.3% and 91.0%, respectively, for IgM. The best sensitivity and specificity were obtained by measuring immunoglobulin A antibodies against GPL core antigen. The level of GPL core antibodies reflected disease activity, since it decreased in cured MAC patients who had responded to chemotherapy. Measurement of serum antibodies against GPL core is useful for both diagnosis and assessment of disease activity in MAC disease of the lung. 相似文献
35.
We studied angiographic findings of 56 patients who were diagnosed as lacunar infarcts in the basal ganglia or deep subcortical white matter based on clinical symptomatology and brain computed tomography. In 26 patients with CT lesions less than 15 mm in diameter, only eight (31%) showed minor angiographic findings. In 30 patients with lesion of 15 mm or more, however, 22 (73%) had abnormal angiographic findings. Fourteen of the 22 patients had minor irregularities, three had 25-75% stenosis, five had 75% less than stenosis at the bifurcation of the common carotid artery or the horizontal portion of the middle cerebral artery. Our findings support the notion that a small lesion on CT can result from an occlusion of the perforating artery itself and a larger lesion is much related to the major vessel or heart diseases, i.e., emboli from the parent artery or heart, obstruction of perforators at their origin by an atheromatous plaque of the horizontal portion of the middle cerebral artery, or terminal zone infarct due to hemodynamically significant stenotic lesion. In patients with a larger deep infarct on CT, further investigation of the arteries in the carotid-axis and heart is important for determination of therapeutic indication. 相似文献
36.
Y Okajima N Chino E Saitoh A Kimura 《Electroencephalography and clinical neurophysiology》1991,80(6):531-535
Somatosensory vertex potentials (SVPs) were examined in 12 healthy subjects in response to painful electrical stimulation of the finger. SVPs consisted of N1, P1, and N2. The average latencies of the 3 peaks were 150, 225, and 350 msec, respectively. The latency and amplitude of each potential were reproducible for each subject. Recovery functions of the SVPs were analyzed in 10 subjects. A pair of stimuli were delivered to the right or left finger with interstimulus intervals (ISIs) of 50, 100, 150, 200, 350, 500 and 650 msec. SVPs partially recovered with the shortest ISI (50 msec). Full recovery could not be obtained even with the longest ISI (650 msec). Differences in recoveries within 650 msec of ISI were not observed between right and left stimulations. To examine the interaction between SVPs evoked by right and left finger stimulation, recovery functions from prior contralateral finger stimulation were analyzed with the same ISIs. SVP recoveries for right after left or left after right patterns of stimulus delivery were nearly the same as those for ipsilateral ones. It is suggested that SVPs are generated at nearly the same site in the sensory pathway regardless of the side stimulated. 相似文献
37.
Hui Liu Tetsuzo Agishi Hideiku Suga Yutaro Hayasaka Satoshi Teraoka Kazuo Ota 《Artificial organs》1995,19(4):324-327
Abstract: Prevention of hyperacute rejection is a difficult and unsolved problem in xenotransplantation. Natural antibodies and complement activation have been known to play an important role in the xenotransplantation between discordant species pairs. In the present study, total blood exchange (TBE) was performed with pyridox-alated-hemoglobin-polyoxyethylene conjugate (PHP) solution (Ajinomoto Co., Inc., Kawasaki, Japan) before cardiac xenotransplantation in order to remove the immunoglobulins and prolong xenograft survival time. Guinea pigs and rats were used as the discordant species combination for donor and recipient. Two groups were established: Group 1, untreated control (n = 8) and Group 2, TBT with PHP solution (n = 8). The exchange blood transfusion was carried out at the rate of 15–20 ml/h utilizing PHP solution using a blood pump. After the blood exchange was processed, hematocrit (Ht) levels dropped to 4 or 5%, and a cardiac xenotransplantation was performed within 24 h. The levels of serum IgA, IgM, and IgG were decreased to less than 25, 25, and 10% of the base line, respectively, after blood exchange. A mean xenograft survival time in Group 2 was prolonged to 472 ± 74 min and to 10.4 ± 1.8 min in Group 1 (p < 0.01). A titer of the anti-guinea pig lymphocytotoxic antibody in rat serum was decreased to almost nil. The data from this study suggest that total blood exchange with PHP solution may be useful in preoperative removal of xenograft antibodies in xenotransplantation. 相似文献
38.
Kazushi Kishi Taizo Takeuchi Tetsuo Sonomura Masashi Kimura Keisuke Kita Morio Sato Masaki Terada 《Cardiovascular and interventional radiology》1997,20(1):63-66
In order to treat fistulated esophageal cancer using a flexible stent, a covered flexible stent was constructed by wrapping
a nitinol stent with a thin sheet of Gore-Tex, preserving the stents original advantages of flexibility and a low-profile
introducer system. This stent was used to perform standard radiotherapy in a case of fistulated esophageal cancer. 相似文献
39.
40.
Takashi Ito Kazuo Shimamura Kiyoshi Shoji Akira Akatsuka Yasuyoshi Kiryu Norikazu Tamaoki Yoshiyuki Osamura 《Virchows Archiv : an international journal of pathology》1993,422(6):487-490
A rare case of urinary bladder carcinoma with granulocyte colony stimulating factor (G-CSF) production was reported. In an 83-year-old female, marked neutrophilia in the peripheral blood decreased from 132,500/mm3 to 3,300/mm3 after tumour resection. The tumour was a transitional cell carcinoma. The serum G-CSF level reduced from 238 pg/ml pre-operatively to normal (60 pg/ml) after the operation. Immunohistochemical investigation of the resected tumour with monoclonal antibody specific for G-CSF revealed positive staining in the carcinoma cells, confirming G-CSF secretion. 相似文献