经直肠超声引导下经会阴125I粒子永久植入治疗前列腺癌的初步经验

目的探讨经直肠超声引导下经会阴125I粒子永久植入治疗前列腺癌的疗效和并发症。方法本组前列腺癌患者5例。年龄61￣83岁,平均70.4岁。临床分期T2bN0M0者2例,T3aN0M0者3例。Gleason评分6分者2例,7分者1例,8分者2例。术前前列腺特异性抗原(PSA)4.5￣17.5ng/ml。T3a期患者植入治疗前先行内分泌治疗。术前制定治疗计划,经直肠超声引导下经会阴125I粒子永久植入操作。术后观察PSA水平变化,连续3次PSA升高即为生化复发,观察术后尿路和直肠并发症发生情况。结果5例患者均术后恢复顺利。术后随访18个月,PSA均明显下降,PSA为0.1ng/ml者3例,0.01ng/ml者1例,0.04ng/m1者1例。5例患者术后均出现不同程度的尿路刺激症状,但6个月后逐渐好转。4例术后出现排便次数增多,术后3个月均好转。未发现尿失禁、直肠溃疡等并发症。结论经直肠超声引导下经会阴125I粒子永久植入治疗前列腺癌的疗效确切,创伤较小。     

抗白色念珠菌鸡卵黄抗体(IgY)的研制

目的：观察鸡蛋黄中抗体的产量、纯度、来源及稳定性。方法：应用白色念珠菌作为抗原免疫25周龄Leghorn鸡，通过改良水溶法（WD）提取蛋黄中抗体IgY，双紫外光测定抗体含量，SDS-APGE电泳检测抗体纯度，Western blot免疫印迹法测定该抗体来源，ELISA检测热处理后的抗体活性。结果：抗体含量13mg/ml蛋黄液，抗体纯度达到95%，Western blot免疫印迹证明该抗体与鸡血清中的IgG具有相同的分子量和抗原性。ELISA检测热处理后的抗体活性，其具有良好的热稳定性。结论：鸡蛋黄内含有丰富的抗体，通过WD水溶提取法可得到高产量，高纯度的特异性抗体IgY，证明其来源于鸡血清中的IgG，对热具有高度稳定性。     

角膜移植术护理探讨

以１５例角膜移植术的护理实践，总结出该手术的护理常规，并对本组病例中发生的并发症的护理进行了讨论，强调护士密切观察病情，有效地处理并嫌下对手术成功的重要性。     

基于MATLAB胎儿心电实时显示

文章介绍了从母亲体中采集到的心电信号，利用MATLAB软件对采集到的心电信号进行准确的数据实时处理，分离出胎儿心电（ECG）信号，实验结果表明，这种方法有一定的实用性。     

Attitudes towards mental illness: testing the contact hypothesis among Chinese student nurses in Hong Kong

This study investigated whether previous contact with mental illness affected the attitudes to mental illness (AMI) of general student nurses in Hong Kong — the contact hypothesis. We employed a quasi-experimental design. We compared the attitudes to mental illness of students who had previous contact with mental illness through having taken a psychiatric secondment with those who had not taken a psychiatric secondment. Also, we compared the AMI of: students who had taken other courses related to mental illness with those who had not; those who had a family history of mental illness with those who had not; and those who lived with a mentally ill relative with those who did not. We found that previous contact with mental illness had no significant effect on the attitudes to mental illness of the students. In other words our findings do not support the contact hypothesis. Our sample expressed positive general attitudes to mental illness when presented with general issues about mental illness. However, their attitudes were less positive when presented with specific issues about mental illness that might impinge upon their daily lives. We discuss the implications of these findings for mental health nursing practice, education and research.     

脑电分频积分定量法测定甜菜碱对清醒家兔脑电图的影响

本文采用脑电分频积分定量法测定甜菜碱对清醒家兔脑电的影响。清醒家兔静注甜菜碱250mg/kg后,出现高幅幔波夹杂低幅快波脑电,自发脑电积分值((?)vs)显著提高。动物安静少动。结果表明甜菜碱有中枢抑制作用。     

核素骨显像在骨转移瘤中的实用价值（附100例分析）

对１００例骨转移瘤进行了分析，阳性率６３．７％，以胸部受累最多。讨论了其它方法报告不同的原因是检查时机、灵敏度、范围和方法不同所致。核素骨显像灵敏度高，检查范围大，是早期寻找骨转移、划分病期、引导病理活检和判断疗效的理想方法。随着（１５３）钐的应用，给骨转移瘤的治疗开辟了一个新途径。确认核素骨显像对转移性骨肿瘤的早期诊断和治疗均有较大的临床价值。