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51.
Jerrold Scott Petrofsky Gurinder Bains Chinna Raju Everett Lohman Lee Berk Michelle Prowse Shashi Gunda Piyush Madani Jennifer Batt 《Archives of dermatological research》2009,301(8):581-585
Numerous studies have examined the effect of local and global heating of the body on skin blood flow. However, the effect
of the moisture content of the heat source on the skin blood flow response has not been examined. Thirty-three subjects, without
diabetes or cardiovascular disease, between the ages of 22 and 32 were examined to determine the relationship between the
effects of dry vs. moist heat applied for the same length of time and with the skin clamped at the same skin temperature on
the blood flow response of the skin. The skin, heated with an infrared heat lamp (skin temperature monitored with a thermocouple)
to 40°C for 15 min, was either kept moist with wet towels or, in a separate experiment, kept dry with Drierite (a desiccant)
between the towels to remove any moisture. Before and after heat exposure of the forearm, blood pressure, heart rate, skin
moisture content, skin temperature, and skin blood flow were recorded. The results of the experiment showed that there was
no change in skin moisture after 15 min exposure to dry heat at 40°C. However, with moist heat, skin moisture increased by
43.7%, a significant increase (P < 0.05). With dry heat, blood flow increased from the resting value by 282.3% whereas with moist heat, blood flow increased
by 386% over rest, a significant increase over dry heat (P < 0.05). Thus, with a set increase in skin temperature, moist heat was a better heating modality than dry heat. The reason
may be linked to moisture sensitivity in calcium channels in the vascular endothelial cell. 相似文献
52.
Gomez EL Gun SC Somnath SD D'Souza B Lim AL Chinna K Radhakrishnan AK 《International journal of rheumatic diseases》2011,14(1):12-17
Aim: The purpose of this study is to compare the prevalence of rheumatoid factor (RF) isotypes and second generation anti‐cyclic citrullinated peptides (anti‐CCP) in Malaysian rheumatoid arthritis (RA) patients. Methods: In this cross‐sectional study, 147 established RA patients from three ethnic groups were recruited from a major rheumatology clinic in Malaysia. Enzyme‐linked immunosorbent assays (ELISA) for serum RF isotypes IgA, IgG and IgM as well as second‐generation anti‐CCP were performed and the prevalence of each auto‐antibody was compared in the three ethnic groups. Results: The anti‐CCP was the most prevalent auto‐antibody in each of the ethnic groups, followed closely by RF IgM and RF IgG. Rheumatoid factor IgA was the least prevalent across all three ethnic groups. The anti‐CCP–RF IgM combination provided the best test sensitivity. Seroprevalence of anti‐CCP was strongly associated with the presence of each of the RF isotypes. The seroprevalence of RF and anti‐CCP did not increase or decrease with advancing age, age at onset and disease duration. Conclusion: When used alone, anti‐CCP provides a diagnostic advantage over RF IgM on the basis of test sensitivity. Considering the high cost of the anti‐CCP assay, step‐wise serum testing with IgM RF followed by anti‐CCP may provide a more economically sensible option to optimize test sensitivity for RA. 相似文献
53.
Samuel J. Offor Chinna N. Orish Eze Chidi Eze Chiara Frazzoli Orish E. Orisakwe 《Transfusion and apheresis science》2021,60(2):103067
Long term health effects of heavy metal exposure from both occupational and environmental settings involve multi-organ toxicities including but not limited to disturbances of neurological, cognitive, and metabolic processes, immune system dysregulation, carcinogenesis and sometimes permanent disabilities. Humans are exposed to toxic metals through various sources and routes of entry. The risk of heavy metal poisoning from donor blood has been the subject of many scientific investigations. In this review we highlight how the access to a safe and adequate blood transfusion with minimal risk of toxic metals to recipients is a public health challenge, especially in developing nations. For quality assurance purposes, blood donors are screened for various blood-borne pathogens, but screening for toxic metal levels is not routine. Evidence from scientific studies used in this review lends credence to the risk of heavy metal poisoning from donors with high blood concentrations of these heavy metals. The risk of toxicity is exceptionally high in vulnerable populations such as neonates and preterm infants, as well as in pregnant women and other individuals with conditions requiring multiple blood transfusions. This is worse in developing countries where some members of the population engage in illegal refining and artisanal mining activities. In order to reduce toxic metal exposure in vulnerable populations, blood meant for transfusion in vulnerable subjects, e.g. children, should be routinely screened for heavy metal concentrations. Patients receiving multiple blood transfusions should also be monitored for iron overload and its attendant toxicities. 相似文献
54.
Elder Abuse and Chronic Pain: Cross‐Sectional and Longitudinal Results from the Preventing Elder Abuse and Neglect Initiative 下载免费PDF全文
Raudah M Yunus MPH Noran N Hairi PhD Wan Y Choo PhD Maw P Tan PhD Farizah Hairi PhD Rajini Sooryanarayana DrPH Norliana Ismail DrPH Shatanapriya Kandiben BSc Devi Peramalah BSc Zainudin M Ali MPH Sharifah N Ahmad MD Inayah A Razak MD Sajaratulnisah Othman PhD Fadzilah HM Mydin MD Karuthan Chinna PhD Awang Bulgiba PhD 《Journal of the American Geriatrics Society》2018,66(6):1165-1171
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Lugova Halyna Andoy-Galvan Jo Ann Patil Sapna S. Wong Yin How Baloch Gul M. Suleiman Adlina Nordin Rusli Chinna Karuthan 《Community mental health journal》2021,57(8):1489-1498
Community Mental Health Journal - Growing prevalence of mental illnesses and the role they play in the global disease burden is an emerging public health issue. The prevalence of depression and... 相似文献
60.
Su Im Ee Karuthan Chinna Mary J. Marret 《Physical & occupational therapy in pediatrics》2016,36(2):117-130
Aims: To translate, culturally adapt, and examine psychometric properties of the Malay version Short Sensory Profile (SSP-M). Methods: Pretesting (n = 30) of the original English SSP established its applicability for use with Malaysian children aged 3–10 years. This was followed by the translation and cross-cultural adaptation of the SSP-M. Two forward and two back translations were compared and reviewed by a committee of 10 experts who validated the content of the SSP-M, before pilot testing (n = 30). The final SSP-M questionnaire was completed by 419 parents of typically developing children aged 3–10 years. Results: Cronbach's alpha of each section of the SSP-M ranged from 0.73 to 0.93 and the intraclass correlation coefficient (ICC) indicated good reliability (0.62–0.93). The seven factor model of the SSP-M had an adequate fit with evidence of convergent and discriminant validity. Conclusions: We conclude that the SSP-M is a valid and reliable screening tool for use in Malaysia with Malay-speaking parents of children aged 3–10 years. The SSP-M enables Malay-speaking parents to answer the questionnaire with better reliability, and provides occupational therapists with a valid tool to screen for sensory processing difficulties. 相似文献