全文获取类型
收费全文 | 19789篇 |
免费 | 1193篇 |
国内免费 | 59篇 |
专业分类
耳鼻咽喉 | 218篇 |
儿科学 | 384篇 |
妇产科学 | 496篇 |
基础医学 | 3363篇 |
口腔科学 | 439篇 |
临床医学 | 1938篇 |
内科学 | 3707篇 |
皮肤病学 | 367篇 |
神经病学 | 1948篇 |
特种医学 | 958篇 |
外科学 | 2972篇 |
综合类 | 143篇 |
一般理论 | 3篇 |
预防医学 | 1051篇 |
眼科学 | 586篇 |
药学 | 1338篇 |
中国医学 | 57篇 |
肿瘤学 | 1073篇 |
出版年
2023年 | 78篇 |
2022年 | 144篇 |
2021年 | 309篇 |
2020年 | 181篇 |
2019年 | 323篇 |
2018年 | 370篇 |
2017年 | 311篇 |
2016年 | 383篇 |
2015年 | 407篇 |
2014年 | 548篇 |
2013年 | 801篇 |
2012年 | 1130篇 |
2011年 | 1088篇 |
2010年 | 751篇 |
2009年 | 688篇 |
2008年 | 1097篇 |
2007年 | 1133篇 |
2006年 | 1158篇 |
2005年 | 1174篇 |
2004年 | 974篇 |
2003年 | 965篇 |
2002年 | 926篇 |
2001年 | 258篇 |
2000年 | 210篇 |
1999年 | 230篇 |
1998年 | 213篇 |
1997年 | 162篇 |
1996年 | 157篇 |
1995年 | 171篇 |
1994年 | 126篇 |
1993年 | 129篇 |
1992年 | 126篇 |
1991年 | 116篇 |
1990年 | 126篇 |
1989年 | 89篇 |
1988年 | 100篇 |
1987年 | 100篇 |
1986年 | 86篇 |
1985年 | 99篇 |
1984年 | 110篇 |
1983年 | 90篇 |
1982年 | 94篇 |
1981年 | 94篇 |
1933年 | 97篇 |
1932年 | 93篇 |
1931年 | 81篇 |
1930年 | 83篇 |
1928年 | 79篇 |
1926年 | 80篇 |
1924年 | 77篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
61.
Urea, a small molecular solute, is the candidate molecule commonly used to understand solute kinetics in both peritoneal dialysis (PD) and hemodialysis. Serum urea or serum urea nitrogen levels are used to calculate measures of dialysis adequacy and nutritional status in patients on dialysis. The kinetic behavior of this molecule is different for a continuous therapy such as PD compared with an intermittent therapy such as hemodialysis. This article presents a simplified approach to understanding urea kinetics on PD. 相似文献
62.
Rechtsanwalt Professor Dr. iur. Karl Otto Bergmann Rechtsanwältin Dr. iur. Carolin Wever 《MedR Medizinrecht》2007,25(5):296-297
Ohne Zusammenfassung 相似文献
63.
64.
65.
Rechtsanwalt Professor Dr. iur. Karl Otto Bergmann Rechtsanwältin Dr. iur. Carolin Wever 《MedR Medizinrecht》2007,25(4):229-230
Ohne Zusammenfassung 相似文献
66.
67.
Maurizio Fava Michael E Thase Charles DeBattista Karl Doghramji Sanjay Arora Rod J Hughes 《Annals of clinical psychiatry》2007,19(3):153-159
BACKGROUND: Partial response, no response, or residual symptoms following antidepressant therapy is common in clinical psychiatry. This study evaluated modafinil in patients with major depressive disorder (MDD) who were partial responders to adequate selective serotonin reuptake inhibitor (SSRI) therapy and excessive sleepiness and fatigue. METHODS: This retrospective analysis pooled the data of patients (18-65 yrs) who participated in two randomized, double-blind, placebo-controlled studies of modafinil (6-week, flexible-dose study of 100-400 mg/day or 8-week, fixed-dose study of 200 mg/day) plus SSRI therapy. Patients (n=348) met criteria for several residual symptoms (Epworth Sleepiness Scale [ESS] score>or=10; 17-item Hamilton Depression Scale [HAM-D] score between 4 and 25; and Fatigue Severity Scale [FSS] score>or=4). RESULTS: Compared to placebo, modafinil augmentation rapidly (within 1 week) and significantly improved overall clinical condition (Clinical Global Impression-Improvement), wakefulness (ESS), depressive symptoms (17-item HAM-D), and fatigue (FSS) (p<.01 for all). At final visit, patients receiving modafinil augmentation experienced statistically significant improvements in overall clinical condition, wakefulness, and depressive symptoms. Modafinil was well tolerated in combination with SSRI. CONCLUSIONS: Results of this pooled analysis provide further evidence suggesting that modafinil is an effective and well-tolerated augmentation therapy for partial responders to SSRI therapy, particularly when patients continue to experience fatigue and excessive sleepiness. 相似文献
68.
Robert W. Mendicino DPM FACFAS Alan R. Catanzariti DPM FACFAS Karl R. Saltrick DPM FACFAS Michael F. Dombek DPM Brandon L. Tullis DPM Trenton K. Statler DPM Brandi M. Johnson DPM 《The Journal of foot and ankle surgery》2004,43(2):82-86
Nineteen patients (20 feet) with severe hindfoot and ankle deformity underwent tibiotalocalcaneal fusion with a retrograde locked intramedullary nail as a limb-salvage procedure. The purpose of this study was to compare the complication rates of this procedure in diabetic versus nondiabetic patients. There were 8 men and 11 women with preoperative diagnoses including Charcot neuroarthropathy, primary osteoarthritis, rheumatoid arthritis, equinocavovarus, posttraumatic osteoarthritis, gouty arthritis, and ankle malunion. Ten of 20 procedures were performed in patients with diabetes. The average patient age was 56 years, and the average postoperative follow-up was 19.8 months. Nineteen of 20 ankles (95%) achieved successful fusion with an average time of 4.1 months. Four patients (21%) required either a fracture brace or an ankle foot orthosis at final follow-up. Five patients (25%) had major complications and 11 patients had minor complications. Major complications included osteomyelitis (n = 2), Charcot arthropathy (n = 2), failure of fixation (n =1), soft-tissue necrosis (n = 1), cardiac arrest (n = 1), cerebral vascular accident (n = 1), and fatal pulmonary embolus (n = 1). All patients with major complications were diabetic, and 14 of 20 combined major and minor complications occurred in patients with diabetes. The complication rate was found to be high in diabetic patients with end-stage deformity undergoing a limb salvage 相似文献
69.
Heinrich Schulze Mönking Wilhelm P. Hornung Karl Stricker Gerhard Buchkremer 《European archives of psychiatry and clinical neuroscience》1997,247(1):31-34
This study examines the correlation between development of expressed emotion (EE) in relatives and course of illness of 99
DSM-III schizophrenic patients. Patients whose relatives were high EE at baseline and at the 2nd CFI approximately 20 months
later had a poor prognosis at the very outset of the study and an unfavourable course of illness. They had a higher rehospitalisation
rate, more symptoms, lower psychosocial assessment, and a poorer 2-year and even 8-year outcome. Patients from families with
a fluctuating EE or a consistently low EE had better courses. Expessed emotion is therefore a valid predictor not only of
symptomatic relapses, but also of other important aspects of schizophrenia. The connection between EE index and course of
illness seerns not to be simply reactive or causal, but complex and non-uniform. 相似文献
70.
Favorable results of coronary artery bypass grafting in patients older than 75 years 总被引:2,自引:0,他引:2
K A Horvath V J DiSesa P S Peigh G S Couper J J Collins L H Cohn 《The Journal of thoracic and cardiovascular surgery》1990,99(1):92-5; discussion 95-6
There is controversy whether the short-term and long-term results of coronary artery bypass grafting in elderly patients justify performing the procedure. Between January 1977 and December 1986, 4580 patients underwent coronary artery bypass grafting, of whom 222 (4.9%) were 75 years old or older (mean 77 years). There were 143 men and 79 women and 139 (63%) were in New York Heart Association class IV. One hundred forty-six patients (66%) had had at least one preoperative myocardial infarction. Myocardial revascularization was performed under emergency conditions in 17 patients (18%). The mammary artery was used in 43%, 96% of the patients received two or more grafts. The mean number of bypass grafts was 3.1 per patient. The overall hospital mortality rate was 10.8% (24/222), 3.6% for elective procedures, 14.9% in urgent cases, and 35% in emergencies. In contrast, the overall early mortality rate was 3.1% in 4358 patients less than 75 years old. Complications occurred in 83 patients (37%). Of the patients discharged from the hospital, 198 were followed up for a mean of 48 months (1 to 130). Actuarial probability of survival was 75% at 48 months. Postoperatively 70% were in New York Heart Association class I or II and only 21% were rehospitalized for cardiac problems. During the follow-up period 77% of the patients were free from angina, and of those experiencing angina the mean time from operation to the first episode was 75 months. Although elderly patients have a somewhat increased operative mortality rate, particularly if operated on urgently or emergently, long-term survival and freedom from angina are excellent and justify continued performance of coronary bypass grafting in selected patients over 75 years of age. 相似文献