全文获取类型
收费全文 | 5502篇 |
免费 | 410篇 |
国内免费 | 48篇 |
专业分类
耳鼻咽喉 | 28篇 |
儿科学 | 123篇 |
妇产科学 | 128篇 |
基础医学 | 636篇 |
口腔科学 | 92篇 |
临床医学 | 602篇 |
内科学 | 1176篇 |
皮肤病学 | 67篇 |
神经病学 | 317篇 |
特种医学 | 306篇 |
外国民族医学 | 1篇 |
外科学 | 1074篇 |
综合类 | 210篇 |
一般理论 | 2篇 |
预防医学 | 318篇 |
眼科学 | 137篇 |
药学 | 346篇 |
1篇 | |
中国医学 | 13篇 |
肿瘤学 | 383篇 |
出版年
2023年 | 49篇 |
2022年 | 107篇 |
2021年 | 197篇 |
2020年 | 98篇 |
2019年 | 158篇 |
2018年 | 181篇 |
2017年 | 158篇 |
2016年 | 148篇 |
2015年 | 169篇 |
2014年 | 238篇 |
2013年 | 272篇 |
2012年 | 446篇 |
2011年 | 415篇 |
2010年 | 231篇 |
2009年 | 210篇 |
2008年 | 289篇 |
2007年 | 293篇 |
2006年 | 288篇 |
2005年 | 269篇 |
2004年 | 224篇 |
2003年 | 234篇 |
2002年 | 194篇 |
2001年 | 76篇 |
2000年 | 67篇 |
1999年 | 59篇 |
1998年 | 76篇 |
1997年 | 58篇 |
1996年 | 59篇 |
1995年 | 43篇 |
1994年 | 33篇 |
1993年 | 33篇 |
1992年 | 40篇 |
1991年 | 35篇 |
1990年 | 30篇 |
1989年 | 45篇 |
1988年 | 35篇 |
1987年 | 28篇 |
1986年 | 34篇 |
1985年 | 29篇 |
1984年 | 21篇 |
1983年 | 19篇 |
1982年 | 30篇 |
1981年 | 18篇 |
1980年 | 20篇 |
1978年 | 15篇 |
1977年 | 19篇 |
1976年 | 23篇 |
1975年 | 17篇 |
1972年 | 22篇 |
1971年 | 21篇 |
排序方式: 共有5960条查询结果,搜索用时 0 毫秒
11.
12.
13.
14.
Q Abdool Karim S S Abdool Karim E Preston-Whyte 《Suid-Afrikaanse tydskrif vir geneeskunde》1992,82(5):360-362
This study assessed the ability and preparedness of staff at family planning clinics in Durban to assist in AIDS prevention by promoting condom use among teenagers. Staff at 12 randomly selected clinics were interviewed to assess their attitudes towards teenagers seeking condoms, the information imparted on AIDS and condom use, constraints faced in delivering services, and their perceived role in controlling the spread of AIDS. Despite their awareness of AIDS, those interviewed perceived their role to be that of promoting contraception. Condoms were perceived as a poor choice of contraceptive and their use was discouraged. The pamphlets dispensed along with condoms were thought to provide adequate information about condom use. Information on AIDS was given only if the clinic attender initiated discussion on the subject. Most of the clinic staff were keen to discuss other issues during their consultations, but felt constrained by the large numbers of people they had to attend to and the lack of adequate facilities. If family planning services are to play a role in controlling the spread of AIDS, the first step must be to make this function part of the overall policy. For there to be effective counselling on AIDS prevention, in-service training of current staff is required, as well as more staff and improvements in facilities to ensure greater privacy. 相似文献
15.
16.
Inhibition of allergic airways inflammation and airway hyperresponsiveness in mice by dexamethasone: role of eosinophils,IL-5, eotaxin,and IL-13 总被引:4,自引:0,他引:4
Eum SY Maghni K Hamid Q Eidelman DH Campbell H Isogai S Martin JG 《The Journal of allergy and clinical immunology》2003,111(5):1049-1061
BACKGROUND: Glucocorticoids inhibit allergen-induced airway eosinophilia and airway hyperresponsiveness (AHR). Whether glucocorticoids mediate their effects on AHR by inhibiting eotaxin and IL-5, 2 of the principal mediators of eosinophilia, or through IL-13, an important mediator of AHR, has not been established. OBJECTIVE: We sought to investigate the effects of glucocorticoids on airway eosinophilia and the expression of IL-5, eotaxin, and IL-13 in relation to the induction of AHR in a murine model of allergic asthma. METHODS: Dexamethasone (4 mg/kg) and mAbs against eotaxin (80 micro g/kg) and IL-5 (100 micro g/kg) singly and in combination were administered to immunized mice before antigen challenge. Airway responsiveness to methacholine was measured in anesthetized and mechanically ventilated animals. Eotaxin, IL-5, and IL-13 in bronchoalveolar lavage fluid (BALF), lung homogenates, or both were measured by means of ELISA. RESULTS: A single antigen challenge induced AHR that lasted at least 10 days. Eotaxin protein and mRNA levels increased in lung tissue but not in BALF after challenge. IL-5 protein and mRNA levels increased both in BALF and in lung tissue. Dexamethasone reduced airway eosinophilia, AHR, and protein and mRNA for eotaxin and IL-5. Anti-murine eotaxin and anti-IL-5 antibodies alone and in combination reduced the ovalbumin-induced airway eosinophilia significantly but failed to inhibit AHR. Both dexa-methasone and anti-IL-5/anti-eotaxin inhibited the increases in lung IL-13 levels after ovalbumin challenge to a similar extent. CONCLUSION: These findings suggest that the inhibition of AHR by the glucocorticoid dexamethasone does not appear to be explained by effects on eosinophilia, eotaxin, IL-5, or IL-13. 相似文献
17.
18.
19.
A. NÆSS 《Scandinavian journal of immunology》1976,5(1-2):165-168
Cerebrospinal fluid (CSF) was allowed to drop straight into Hanks's balanced salt solution. After centrifugation the pellet was resuspended and mixed with sheep erythrocytes. The mixture was further handled as in the E-rosette test with peripheral blood lymphocytes. CSF from 20 individuals were investigated, and rosette-forming cells (RFC) were found in all. Six patients with normal fluid had between 46% and 83% RFC. Four patients with multiple sclerosis had increased numbers of RFC (94%-96%). Low numbers of RFC were found in one patient with cerebellar ataxia and in one of two patients with acute viral meningitis. With this technique RFC can be counted even in normal CSF with a 3-ml sample. 相似文献
20.