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101.
E Sadeghi MR Kadivar AK Ghadimi Moghadam GR Pooladfar N Sadeghi 《Iranian Red Crescent Medical Journal》2011,13(1):47-51
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare inflammatory bone disease. It is a diagnosis of exclusion based on the clinical, radiological and pathological criteria. The awareness of the corresponding feature can help avoid of unnecessary diagnostic procedures and prolonged antibiotic therapy. We present a case of 4.5 year old girl, diagnosed with CRMO who were followed for 6 months as a case of chronic bacterial osteomyelitis and received long course of antibiotic therapy. 相似文献
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Strongyloides stercoralis is an intestinal nematode, endemic in tropical countries. The parasite has a complex life cycle, causing a long-lived auto infection in hosts. It may remain asymptomatic or with minor symptoms; the dormant carrier state of the illness may persist for a long period of time. Inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC), commonly treated with immunosuppressive drugs is a well-known condition predisposing individuals to various infections. The condition is more prevalent among immunocompromised patients; the diagnosis of which, however, is troublesome in such individuals. The present article reports a 45- year-old female with gastric strongyloides stercoralis infection while receiving the treatment for her underlying UC. Strongyloides stercoralis can easily be missed especially in IBD patients in the absence of accompanying diarrhea or any symptom of lower GI discomfort because it presents with various manifestations including multiple GI symptoms, multiple stool exams and special attention to peripheral eosinophilia are specially important but not so sensitive or specific. 相似文献
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106.
Ferrante G Baldissera S Moghadam PF Carrozzi G Trinito MO Salmaso S 《European journal of epidemiology》2011,26(3):211-219
Monitoring perceptions, knowledge, attitudes and behaviors of populations during pandemic flu outbreaks is important as it
allows communication strategies to be adjusted to meet emerging needs and assessment to be made of the effects of recommendations
for prevention. The ongoing Italian Behavioral Risk Factor Surveillance System (PASSI) offered the setting for investigating
people’s opinions and behaviors regarding the A/H1N1 pandemic. PASSI surveillance is carried out in 126/148 Italian Local
Health Units (LHU) through monthly telephone interviews administered by public health staff to a random sample of the resident
population 18–69 years. In fall 2009 additional questions exploring issues related to the A/H1N1 flu were added to the standard
questionnaire. The pandemic module was administered on a voluntary basis by the 70 participating LHUs from November 2nd, 2009
to February 7th, 2010; 4 047 interviews were collected. Overall 33% of respondents considered it likely that they would catch
flu, 26% stated they were worried, 16% reported having limited some daily activities out of home and 22% said they would accept
vaccination if offered. All these indicators showed a decreasing trend across the four-month period of observation. The most
trusted sources of information were family doctors (81%). Willingness to be vaccinated was associated with worry about pandemic,
age, sex, having a chronic disease and timing of the interview. The surveillance allowed us to gather relevant information,
crucial for devising appropriate public health interventions. In future disease outbreaks, systems monitoring people’s perceptions
and behaviors should be included in the preparedness and response plans. 相似文献
107.
Changes in cerebrospinal fluid nerve growth factor levels during chick embryonic development 总被引:1,自引:0,他引:1
Farhad Mashayekhi Majid Azari Lotfali Masomi Moghadam Meysam Yazdankhah Mohammad Naji Zivar Salehi 《Journal of clinical neuroscience》2009,16(10):1334-1337
In the early stages of brain development, cells within the ependymal lining of the neural tube are thought to secrete cerebrospinal fluid (CSF), the so-called neural tube fluid (NTF), whereas before fusion of the neural folds, the neuroepithelium that lines the inside of the neural tube is in contact with amniotic fluid. As the neural tube closes, a membrane formed from these cells invaginates to form the specialized choroid plexus. The choroid plexus is a highly vascularized epithelial cell structure that secretes proteins, including growth factors, into the CSF. Embryonic CSF (e-CSF) contains high concentrations of proteins compared to adult CSF. CSF has been reported to contain nerve growth factor (NGF) and other neurotrophic factors. In this study, total protein concentration and NGF level in e-CSF samples from chick embryos were measured using a dye-based protein assay, enzyme-linked immunosorbent assay (ELISA) and Western blot. The total protein concentration and NGF levels in the CSF decreased from days E10 to E16. There was a rapid increase in total protein content on days E17 and E18, and thereafter the levels decreased from day E19 to day E21. Days E17 and E18 coincide with the onset of neuron migration, proliferation and organization of the cytoarchitecture of the developing cerebral cortex. After that time the total protein concentration and NGF levels decrease until hatching. Since CSF is in contact with the cerebral cortical germinal epithelium, changes in the protein concentration in the CSF could affect neuroepithelial cell proliferation, survival and migration. It is concluded that NGF is not only a constant component of CSF during chick embryogenesis but it might also be involved in cerebral cortical development. 相似文献
108.
Non–small cell lung cancer clinical trials requiring biopsies with biomarker‐specific results for enrollment provide unique challenges
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Marshall L. Spiegel JD Jonathan W. Goldman MD Brian R. Wolf BS Danielle J. Nameth BS Tristan R. Grogan MS Aaron E. Lisberg MD Deborah J. L. Wong MD PhD Blanca A. Ledezma MSN Melody A. Mendenhall MSN Scott J. Genshaft MD Antonio J. Gutierrez MD Fereidoun Abtin MD W.Dean Wallace MD Carlos R. Adame BS Jordan R. McKenzie RN Phillip A. Abarca BS Alice J. Li BS Jennifer L. Strunck BS Sina Famenini BS James M. Carroll BS D. Andrew Tucker BA Lauren M. Sauer BA Nima M. Moghadam MD David A. Elashoff PhD Christina D. Abaya BA Meghan B. Brennan PhD Edward B. Garon MD 《Cancer》2017,123(24):4800-4807
109.
Siamak Rimaz Anoush Dehnadi Moghadam Mohammadreza Mobayen Mehdi Mohammadi Nasab Sheyda Rimaz Roghayeh Aghebati Zakiyeh Jafaryparvar Enayatollah Homaie Rad 《Burns : journal of the International Society for Burn Injuries》2019,45(8):1864-1870
BackgroundThe second most abundant mineral in the body, phosphorus (P), is absorbed in the small intestine after ingestion enhanced by 1,25-dihydroxy vitamin D, and its excretion is exclusively regulated by the kidney. It is clinically significant, aside from its disturbance in burn ICU patient’s P mechanism. The increasing rate of morbidity and mortality among the patients can be associated with severe hypophosphatemia. The current study aimed at investigating the changes in serum P levels in the early period after burns, the relationship between serum P level and TBSA (total body surface area) of burn, and the impact of hypophosphatemia on patients’ clinical outcomes.Material and methodsThe current prospective, observational study was conducted on 137 patients hospitalized in the burn intensive unit (BICU) of Velayat Sub-specialty Burn and Plastic Surgery Center from December 2015 to May 2017. According to the TBSA percentage, the patients were divided into three groups. The level of serum P was determined in the 1st, 3rd, 5th, 7th, and 9th days of hospital stay and before discharge. To evaluate the trend of P changes in the sixtime-points, the average changes along with 95% confidence intervals (CI) were used for multivariate analysis of variance with repeated measures (repeated measures ANOVA). A P-value of 0.05 or less was considered statistically significant. The analyses were performed using SPSS software, version 19 (SPSS Inc.).ResultsTotally, 137 patients (70% male, mean age 32 ± 21years, and TBSA 32.6 ± 14%) were included in the study. The overall incidence of hypophosphatemia was 75.1%. Hypophosphatemia developed as early as 1.66 ± 0.136 (95%CI: 1.4–1.9) days after injury. The highest decrease in the serum P level was observed on the 3rd and 5th days after burn as 2.78 mg/dL and 2.85 mg/dL, respectively (P-value = 0.001). A correlation was observed between TBSA and serum P level. The mean serum P level decreased with increasing the percentage of burns. There was a correlation between serum P level and mortality; therefore, a decrease in serum P level increased the patient's mortality rate (P < 0.05).ConclusionThe current study highlighted that hypophosphatemia is often observed in patients with burn injuries during their hospitalization. It is potentially beneficial to identify patients at risk of hypophosphatemia. Therefore, it is suggested that P level be assessed regularly in patients with burn injuries for the timely initiation of P replacement therapy. 相似文献
110.
Ezatollah Fazeli Moghadam Artashes Tadevosyan Ebrahim Fallahi Reza Goodarzi 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2017,11(1):7-11