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71.
Objective : To describe the obstetric and perinatal factors, in particular the method of delivery, associated with development of a subgaleal haematoma (SGH) and to determine the outcome of survivors with this type of birth trauma. Methodology : Perinatal and obstetric data were retrospectively reviewed for 37 infants admitted to the neonatal unit of the sole tertiary paediatric referral hospital in Western Australia with an SGH, over a 24 year period from 1970 to 1993. These data were compared to data for all Western Australian births. The long-term outcome was obtained through medical and private paediatric records for 26 of these infants. Results : All except one of the neonates had instrumental deliveries; 89% had a vacuum extractor applied to the head at some stage of delivery compared to 10% of the general population of births in Western Australia. There was also a significantly increased risk of failure of attempted vacuum extraction. Of the cases where a vacuum extraction was attempted, 45% also had forceps applied to the head. Coagulopathy was associated with the severity of the SGH. There was also a high frequency of occurrence (40%) of associated head trauma such as intracranial haemorrhage, skull fracture and cerebral oedema, as well as neonatal encephalopathy (73%). The occurrence of these associated features did not correlate significantly with the severity of SGH. Minor complications of SGH included jaundice and facial bruising. There was an excess mortality associated with SGH; however, the long-term outcome for neonatal survivors with this disorder was good. None of the cases studied subsequently developed cerebral palsy or intellectual disability, and minor neurological sequelae only were documented in four infants. Conclusions : SGH is an uncommon type of birth trauma, and is associated with delivery or attempted delivery by vacuum extraction. The most commonly associated clinical problems were hypovolaemia and coagulopathy. The long-term outcome for neonates with this condition is good. 相似文献
72.
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74.
Dorresteijn LD Kappelle AC Scholz NM Munneke M Scholma JT Balm AJ Bartelink H Boogerd W 《European journal of cancer (Oxford, England : 1990)》2005,41(7):1026-1030
Patients treated for head and neck tumours with local radiotherapy (RT) on the neck harbour an increased risk of stroke. This may be due to accelerated atherosclerotic changes within the RT-field; however, the real impact of local RT on the carotid artery remains debatable. The aim of the present study was to assess the difference in carotid wall thickness (intima-media thickness) in 42 unilaterally irradiated parotid tumour patients by performing B-mode ultrasonography. A mean difference in intima-media thickness (IMT) of the irradiated compared with the non-irradiated carotid artery of 0.30 mm (P=0.031) was found. A significant correlation was established with a longer post-RT interval (P=0.008). RT on the neck is associated with increased thickening of carotid IMT. Screening and treatment of additional cerebrovascular risk factors which contribute to further IMT thickening and stroke development is recommended, especially in radiotherapy patients with a favourable prognosis. 相似文献
75.
A 9-year-old girl presented with an acute right-sided hemiparesis. Initially, the clinical presentation and stable vasculopathic abnormalities on MR and conventional angiography were suspicious of a so-called "transient cerebral arteriopathy". Mild but persistent pleocytosis and an elevated CSF IgG index led to an extensive search for infectious and immunological causes of cerebral vasculitis, eventually revealing neuroborreliosis. Although rare, infectious and potentially treatable causes of arterial ischemic stroke should be considered in every child with a documented cerebral arteriopathy. 相似文献
76.
77.
Early depressive symptoms after stroke: neuropsychological correlates and lesion characteristics 总被引:28,自引:0,他引:28
Nys GM van Zandvoort MJ van der Worp HB de Haan EH de Kort PL Kappelle LJ 《Journal of the neurological sciences》2005,228(1):27-33
OBJECTIVE: To examine the relation between depressive symptoms and specific cognitive functions in patients with a recent stroke and to examine associations with lesion characteristics. METHODS: We studied 126 of 183 consecutive patients within 3 weeks after a first-ever symptomatic stroke (mean interval, 8.3+/-4.3 days). Presence and severity of depressive symptoms was assessed with the Montgomery Asberg Depression Rating Scale. Neuropsychological functioning was examined by means of a detailed neuropsychological examination covering six cognitive domains. We included a healthy control group (N=75) to obtain normative data for the neuropsychological examination. Functional impairment was measured with the modified Barthel Index and the modified Rankin Scale. Symptomatic and preexistent lesion characteristics were determined on CT or MRI. RESULTS: Of the included patients, 40% demonstrated mild and 12% moderate to severe depressive symptoms. Severity of depressive symptoms was related to lesion volume (p=0.008), functional impairment (all p<0.004), and degree of overall cognitive impairment (p=0.005). After adjustment for lesion size, a specific neuropsychological profile emerged in patients with moderate to severe depressive symptoms, affecting primarily memory, visual perception, and language (all p<0.05). No association was found between severity of depressive symptoms and lesion location, presence of preexistent lesions (white matter lesions and silent infarcts), and demographic factors (age, education, and gender). CONCLUSIONS: Moderate or severe symptoms of depression in the early stage poststroke are associated with a specific pattern of cognitive impairment, lesion size, and functional status. We suggest that depressive symptoms early after stroke are, at least in part, a reactive phenomenon secondary to severe cognitive and functional deficits. 相似文献
78.
Kappelle LJ 《Nederlands tijdschrift voor geneeskunde》2004,148(40):1953-1955
Headache and transient neurological deficits can occur both in patients with migraine and in patients suffering a transient ischaemic attack (TIA). Consequently differentiating between these two disorders may be difficult. Recently, silent cerebral infarcts and ischaemic lesions in the subcortical white matter were found to be associated with migraine and in particular, with migraine with aura. The predominance of cerebellar infarcts in these patients is difficult to understand. Whether ischaemic damage in the brain of patients with migraine should be managed in a manner similar to that of patients with TIAs, should be the subject of future research. 相似文献
79.
Treatment or prevention of complications of acute ischemic stroke 总被引:11,自引:0,他引:11
Both neurologic and medical complications influence outcome after stroke. Space-occupying supratentorial infarcts can cause
transtentorial or uncal herniation, which leads to death. Treatments aimed at reducing intracranial pressure in patients with
such infarcts are of unproven value. Mass-producing cerebellar infarction may lead to brainstem compression and obstructive
hydrocephalus. These lesions often are treated surgically. Although anticonvulsants are not indicated for prophylaxis, the
occurrence of epileptic seizures mandates treatment to prevent recurrences. Depression is common in the acute stage of stroke,
but is probably not more prevalent after stroke than after myocardial infarction. Although dysphagia is common, it usually
is a transient problem. Patients with a decrease of consciousness or brainstem dysfunction usually need tube feeding for a
certain period of time. Medical complications, such as fever, infections, hyperglycemia, cardiac disorders, pressure sores,
and deep venous thrombosis, are associated with a poor prognosis and should be treated as early as possible. Measures to prevent
these complications are part of general care. Hypertension is very common during the week after stroke and should be treated
only in case of extremely high values or malignant hypertension. A multidisciplinary approach in the stroke unit is necessary
to prevent and manage complications in the acute phase of stroke. 相似文献
80.
AIM: To study the experience of, training in, and confidence in the transportation of critically ill neonates amongst paediatric trainees in one UK region. DESIGN: An anonymized questionnaire was sent to all middle grades with paediatrics National Training Numbers from the Trent region. RESULTS: The response rate was 78%. Less than half (45%) of the respondents reported receiving any training in the transportation of neonates, either in the UK or abroad; 45% (30/66) of the trainees reported having performed 10 or fewer neonatal transfers. The self-perceived confidence for transporting neonates was scored on a 10-point scale, to produce a "confidence score", the median score being 7 (IQ range 5, 8). Both as a group and individually, the trainee paediatricians were more confident in transporting neonates than older infants or children (p < 0.0001). Using multiple analysis of covariance, it was found that the most important and significant variables affecting the "confidence scores" for the inter-hospital transportation of critically ill neonates were receipt of any relevant transport training, and the current frequency of transports performed. CONCLUSIONS: Many training-grade paediatricians lack both the experience and training in transporting critically ill neonates, factors that were found to affect their confidence in transferring sick neonates. As the overwhelming majority of neonatal transports in the UK are still arranged by individual units and performed by training-grade paediatricians, concerns regarding both the safety and effectiveness of the current service provision for the inter-hospital transfer of critically ill neonates remain valid. 相似文献