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41.
Duman EN Kesim M Kadioglu M Ulku C Kalyoncu NI Yaris E 《Progress in neuro-psychopharmacology & biological psychiatry》2006,30(2):292-296
PURPOSE: Many studies have reported both a gender difference in the rates of depression and its treatment by using any of the widely used antidepressant drug groups. Some studies suggest that females respond more poorly to tricyclic antidepressants than males and appear to respond better to selective serotonin reuptake inhibitors (SSRI). There is no study investigating the analgesic/antinociceptive effects of antidepressant drugs on the basis of gender difference. In this study, we aimed to investigate the antinociceptive effect of paroxetine on the basis of gender difference. METHODS: The antinociceptive effect of paroxetine was tested using hot plate test in Balb/c mice (30-40 g). The animals were divided into eight groups on the basis of gender. FINDINGS: While paroxetine did not induce an antinociceptive effect in both sex at a dose of 1 mg kg(-1), it showed significant antinociceptive effects in both sex at a dose of 5 or 10 mg kg(-1). None of the doses of paroxetine revealed a gender difference in its antinociceptive action. CONCLUSION: There are several studies showing positive or negative evidence on the gender difference of paroxetine's antidepressant effect, but in the literature there is no study about the gender difference of paroxetine's or any other SSRI drug's antinociceptive effect. In conclusion, our results do not show any gender difference in antinociceptive effect of paroxetine that may be important especially when it would be used as an adjuvant agent in some painful conditions. 相似文献
42.
Serhat Celikel Sacide Rana Isik Ahmet Ugur Demir Gul Karakaya Ali Fuat Kalyoncu 《The Journal of asthma》2013,50(8):710-714
Background. Rhinitis and asthma are common comorbidities. The aim of this study was to determine the risk factors for asthma and other allergic diseases in seasonal rhinitis (SR) patients. Methods. Records of 922 patients diagnosed as SR between 1991 and 2005 were evaluated retrospectively. Patients were grouped according to the results of our standard skin prick tests as follows: I-No sensitization: no sensitization to any allergen; II-Mono-pollen sensitization: sensitization to only one pollen allergen; III-Poly-pollen sensitization: sensitization to more than one pollen allergen; IV-Mite sensitization: sensitization to mite with or without any other allergen sensitization. Results. The mean age of the patients was 29.5 ± 9.6 and 587 patients (63.2%) were females. Age at onset of SR was median 21 years (16–29 years). Of the 922 patients, 99 had no sensitization, 335 had poly-pollen sensitization, 346 had mono-pollen sensitization, and 142 had mite sensitization. The most prevalent allergens were P. pratense (85.3%) and O. europae (31.5%). No sensitization group as compared to poly-pollen sensitization group had significantly higher prevalence of asthma as a single accompanying disease (14.1%, p < 0.05). Mono-pollen sensitization was significantly associated with lower risk of any accompanying allergic disease (OR: 0.7, 95% CI 0,5–0,9) while no sensitization group (OR: 2.8, 95% CI 1.3–5.9) and mite sensitization were associated with asthma (OR: 2.3, 95% CI 1.2–4.4). Conclusion. SR is a condition that presents with different phenotypes. The group with no sensitization and mite sensitization has the highest prevalence of asthma while SR patients with mono-pollen sensitization are unlikely to have an accompanying allergic disease, including asthma. 相似文献
43.
Bilgin Emre Hayran Mutlu Erden Abdulsamet Armağan Berkan Sarı Alper Kılıç Levent Akdoğan Ali Karadağ Ömer Bilgen Şule Apraş Kiraz Sedat Ertenli İhsan Kalyoncu Umut 《Clinical rheumatology》2019,38(6):1699-1706
Clinical Rheumatology - To identify several clinical and/or laboratory parameters which can differentiate adult-onset Still’s disease (AOSD) from other causes of fever of unknown origin (FUO)... 相似文献
44.
45.
Sevim Bavbek Seçil Kepil Özdemir Beyza Doğanay Erdoğan Işıl Karaboğa Suna Büyüköztürk Aslı Gelincik İnsu Yılmaz Özlem Göksel Adile Berna Dursun Gül Karakaya Ali Fuat Kalyoncu Ferhan Özşeker Gülden Paşaoğlu Karakış Ferda Öner Erkekol Gözde Köycü Metin Keren Ilaria Baiardini Antonino Romano 《Quality of life research》2016,25(1):101-109
46.
Asthma phenotypes in Turkey: a multicenter cross‐sectional study in adult asthmatics; PHENOTURK study
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47.
Korcan Aysun Gonen Zeynep Yazici Gokhan Gokalp Ayse Kalyoncu Ucar 《Pediatric radiology》2013,43(2):189-195
Background
Rickets is a complication of infantile osteopetrosis and pre-treatment recognition of this complication is important.Objective
To describe four children with infantile osteopetrosis complicated by rickets (osteopetrorickets) and review the relevant literature.Materials and methods
Retrospective chart analysis of four infants with osteopetrorickets and a systematic review of the relevant literature.Results
We saw five children with infantile osteopetrosis, of whom four had superimposed rickets, for a period of 12 years. The review of the literature (including the current four children), yielded 20 children with infantile osteopetrorickets. The children ranged in age from 2 months to 12 months. In all children, hepatosplenomegaly was found. Sixteen (80%) children had visual impairments and eight (40%) children had hearing impairments. Serum calcium-phosphorus product was less than 30 in 18 children (90%). Twelve children (60%) were hypocalcemic and 18 (90%) were hypophosphatemic. In all children, the radiological examination demonstrated diffuse bony sclerosis and metaphyseal splaying and fraying of long bones. Five children (25%) had pathological fracture of extremities and 15 (75%) had rachitic rosary.Conclusion
Rickets as a complication to infantile osteopetrosis is not uncommon. Skeletal roentgenograms are of critical importance in the diagnosis of both osteopetrosis and superimposed rickets. 相似文献48.
49.
Emel Kurt Selma Metintas Ilknur Basyigit Ismet Bulut Evsen Coskun Sennur Dabak Figen Deveci Fatma Fidan Hasan Kaynar Esra Kunt Uzaslan Kevser Onbasi Sibel Ozkurt Gulden Pasaoglu Sami Sahan Unal Sahin Kivilcim Oguzulgen Fusun Yildiz Dilsad Mungan Arzu Yorgancioglu Bilun Gemicioglu A. Fuat Kalyoncu for the PARFAIT Study of Turkish Thoracic Society Asthma-Allergy Working Group 《Pediatric allergy and immunology》2007,18(7):566-574
The Prevalence And Risk Factors of Allergies in Turkey (PARFAIT) study was planned to evaluate prevalence and risk factors of asthma and allergic diseases and also to find out which geographical variables and/or climatic conditions play a role determining the prevalence of allergic diseases in Turkish school children. Study was planned as cross-sectional questionnaire-based. About 25,843 questionnaires from 14 centers were appropriate for analysis. Parental history of allergy, having an atopic sibling and other atopic disease in index case was significant risk factors for all allergic diseases. Breast feeding decreased the risk of current asthma (OR: 0.92, CI: 0.86-0.99) and wheezing (OR: 0.93, CI: 0.87-0.99) but not allergic rhinitis and eczema. Respiratory infection in the past was an important risk factor for the occurrence of allergic diseases especially for asthma which was increased 4.53-fold. Children exposed to household smoke were significantly at higher risk of asthma, wheezing, and allergic rhinitis (OR: 1.20, CI: 1.08-1.33; OR: 1.21, CI: 1.09-1.34; and OR: 1.32, CI: 1.21-1.43, respectively). All allergic diseases were increased in those children living in areas which have altitude of below 1000 m and mean yearly atmospheric pressure above 1000 mb. The study has suggested that household and country-specific environmental factors are associated with asthma, wheezing, allergic rhinitis, and eczema risk during childhood in Turkey. 相似文献
50.