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71.
Parathyroid adenomas evaluated by Tl-201/Tc-99m pertechnetate subtraction scintigraphy and high-resolution ultrasonography 总被引:2,自引:0,他引:2
Winzelberg GG; Hydovitz JD; O'Hara KR; Anderson KM; Turbiner E; Danowski TS; Lippe RD; Melada GA; Harrison AM 《Radiology》1985,155(1):231-235
Thallium-201/technetium-99m pertechnetate subtraction scintigraphy of the parathyroid glands was performed in a prospective study of 33 patients who had undergone bilateral neck exploration for elevated serum calcium and serum parathyroid hormone levels. In 31 cases, the Tl-201/Tc-99m subtraction technique yielded an overall sensitivity of 81%, specificity of 99%, and accuracy of 94% for identifying solitary parathyroid adenomas. Tl-201/Tc-99m subtraction scintigraphy correctly identified 73% of parathyroid adenomas weighing less than 499 mg, 79% of those weighing 500-1,499 mg, and 100% of adenomas weighing more than 1,500 mg. In a subgroup of 24 patients with solitary parathyroid adenomas who underwent both scintigraphy and high-resolution sonography, the sensitivity, specificity, and accuracy of both procedures were similar. 相似文献
72.
Computed tomographic appearance of the bulging annulus 总被引:6,自引:0,他引:6
73.
Thoracic wall involvement by Hodgkin disease and non-Hodgkin lymphoma: CT evaluation 总被引:6,自引:0,他引:6
Thoracic computed tomographic (CT) scans of 250 patients with newly diagnosed or recurrent lymphoma revealed thoracic wall involvement in 24 patients (11 with Hodgkin disease, 13 with non-Hodgkin lymphoma). Thoracic wall involvement occurred without contiguous mediastinal or parenchymal involvement in 17 patients. Of these, 13 patients had masses beneath the pectoralis muscles or within the breast, and four had masses arising from the ribs. Five additional patients had mediastinal masses with thymic involvement and parasternal extension through the thoracic wall. Pulmonary parenchymal lymphoma with thoracic wall invasion was noted in the remaining two patients. In five of nine patients receiving radiation therapy, treatment plans were modified by CT demonstration of thoracic wall lymphoma. 相似文献
74.
75.
Makras P Papadogias D Samara C Zetos A Kaltsas G Piaditis G Chu AC 《Hormones (Athens, Greece)》2004,3(1):59-64
We describe a 57-year old female with the diagnosis of skull and meningeal Langerhans' cell histiocytosis who was treated with the combination of azathioprine and methotrexate. Although the skull lesions improved considerably on this regimen, the patient developed diabetes insipidus while the anterior pituitary function remained intact. 相似文献
76.
The value of the low-dose dexamethasone suppression test in the differential diagnosis of hyperandrogenism in women 总被引:6,自引:0,他引:6
Kaltsas GA Isidori AM Kola BP Skelly RH Chew SL Jenkins PJ Monson JP Grossman AB Besser GM 《The Journal of clinical endocrinology and metabolism》2003,88(6):2634-2643
We studied 211 hyperandrogenic women with respect to clinical presentation, basal androgen levels, and the degree of cortisol and androgen suppression during a 48-h low-dose (2 mg) dexamethasone-suppression test (LDDST) to exclude ovarian and adrenal tumors. In 42 women with elevated testosterone levels, 21 of whom failed to suppress testosterone during the LDDST, the response of serum androgen levels during a 4-wk administration of 7.5 mg prednisolone in a reverse circadian regimen was also assessed. These results were compared with an additional 17 patients with histologically proven androgen-secreting tumors. Clinical presentation alone was suggestive of a virilizing tumor in 70% of patients with tumors. Serum testosterone, although occasionally only marginally elevated, was the sole androgen that was elevated in every patient with a tumor. After the LDDST, none of the patients with tumors obtained either a greater than 40% reduction or normalization of the previously elevated testosterone levels, whereas 88% of patients with nontumorous hyperandrogenism showed either normalization or suppression of more than 40%. With one exception, all of the patients with nontumorous hyperandrogenism who showed inadequate suppression of testosterone during the LDDST, and were treated with prednisolone, normalized the previously elevated androgens after 1 month of administration. In summary, in women presenting with hyperandrogenism, lack of testosterone suppression during the LDDST is associated with 100% sensitivity and 88% specificity in distinguishing patients with ovarian and adrenal androgen-secreting tumors from patients with nontumorous hyperandrogenism in this small series. The LDDST is an easy to perform screening test that can also identify causes of hyperandrogenism due to altered glucocorticoid secretion. 相似文献
77.
刑事警察心理健康调查分析 总被引:2,自引:0,他引:2
①目的了解刑事警察的心理健康状况,为心理干预提供依据。②方法对济宁市刑警队员进行症状自评量表(Symptom Checklist 90.SCL-90)、焦虑自评量表(Self—rating Anxiety state,SAS)、抑郁自评量表(Self—rating Depression scale,SDS)评定。③结果济宁市刑警队员的SCL-90、SAS、SDS量表评分与全国常模相比存在显著性差异。④结论。刑事警察职业是一种特殊职业,该职业对队员的心理健康有显著的影响,这种影响随着从事刑警工作时间的不同而改变。 相似文献
78.
目的探讨黄芪注射液抗肝纤维化及对TGF-β1、Col-Ⅰ表达的影响。方法将35只SD大鼠随机分为正常对照组、CCl4诱导肝纤维化模型组和黄芪干预组。至造模第10周,处死所有大鼠,采用PV免疫组化方法检测Col-Ⅰ在各组肝组织中的表达,ELISA法检测TGF-β1在各组血清中的表达。结果经CCl4诱导成功建立大鼠肝纤维化模型,随着肝纤维化程度的进展,肝组织中Col-Ⅰ和血清中TGF-β1表达明显增强。在正常对照组、黄芪干预组和肝纤维化模型组肝组织中Col-Ⅰ表达的平均光密度值分别为0.298、0.315、0.503,模型组与前两组比较差异均有显著性(P〈0.01),而黄芪干预组与正常组肝组织比较差异无统计学意义(P〉0.05)。在正常对照组、黄芪干预组和肝纤维化模型组大鼠血清中TGF-β1表达含量分别为491.29pg/L、629.91pg/L、959.09pg/L,呈递增趋势。模型组与前两组比较差异均有显著性(P〈0.01),黄芪干预组与正常组比较其表达含量无显著差异(P〉0.05)。结论黄芪注射液可以显著抑制实验性肝纤维化大鼠模型的肝纤维化,这种抑制作用可能与抑制I型胶原蛋白及TGF-β1的表达有关。 相似文献
79.
80.
Intracranial abnormalities in infants treated with extracorporeal membrane oxygenation: imaging with US and CT 总被引:1,自引:0,他引:1
Findings at neuroimaging in 100 consecutive infants treated with extracorporeal membrane oxygenation (ECMO) are presented. Imaging in these infants consisted of pretreatment cranial ultrasonography (US), daily US studies while on ECMO, and follow-up cranial computed tomography (CT) after treatment. There were findings of abnormalities in 43 patients. Thirty had intracranial bleeding, often of unusual extent and distribution. Thirteen additional infants had nonhemorrhagic abnormalities alone. Bleeding considered to be major was seen in 12% of infants. Large parenchymal hemorrhages and infarcts, cerebellar hemorrhages, and diffuse edema were the most significant abnormalities, with a 50% mortality (eight of 16 patients). No lateralization was noted with respect to distribution of bleeding sites or areas of nonhemorrhagic abnormalities. US was a sensitive but imperfect screening tool for intracranial abnormalities. Abnormalities missed with US included peripheral and small parenchymal lesions, subarachnoid hemorrhage, cerebral atrophy, and sagittal sinus thrombosis. 相似文献