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排序方式: 共有4792条查询结果,搜索用时 18 毫秒
201.
Yoshida H Mamada Y Taniai N Mizuguchi Y Kakinuma D Ishikawa Y Kanda T Matsumoto S Bando K Akimaru K Tajiri T 《Journal of Hepato-Biliary-Pancreatic Surgery》2008,15(2):178-182
Background/Purpose According to the General rules for the clinical and pathological study of primary liver cancer, compiled by the Liver Cancer Study Group of Japan, ruptured hepatocellular carcinoma (HCC) is classified as stage 4, even
if the tumor is small and solitary. We examined the long-term results of elective hepatectomy for the treatment of ruptured
HCC.
Methods A first hepatectomy was performed without operative death in 193 patients with HCC. Ten patients had ruptured HCC (ruptured
group) and 183 patients had nonruptured HCC (nonruptured group). The extension of HCC was macroscopically classified as stage
1 in 23 patients, stage 2 in 71, stage 3 in 53, and stage 4 in 46.
Results Cumulative survival rates in the ruptured group at 1, 5, and 10 years were 90.0%, 67.5%, and 20.3%, respectively. The cumulative
survival rate was lower in patients with stage 4 disease in the nonruptured group than that in patients in the ruptured group
(P < 0.05). Cumulative survival rates did not differ significantly between patients in the ruptured group and those with stage
2 or stage 3 disease.
Conclusions Survival rates after elective hepatectomy in patients with ruptured HCC are good, even if the disease is classified as stage
4. 相似文献
202.
Tetsuaki Ban Shin-ichiro Fujiwara Rui Murahashi Hirotomo Nakajima Takashi Ikeda Sae Matsuoka Yumiko Toda Shin-ichiro Kawaguchi Shoko Ito Takashi Nagayama Kento Umino Daisuke Minakata Hirofumi Nakano Kaoru Morita Masahiro Ashizawa Chihiro Yamamoto Kaoru Hatano Kazuya Sato Ken Ohmine Yoshinobu Kanda 《Internal medicine (Tokyo, Japan)》2022,61(7):989
Objective Peripherally inserted central catheters (PICCs) are widely used in patients with hematologic malignancies. However, the risks of PICC-related complications during chemotherapy for acute myeloid leukemia (AML) are not fully understood. Methods We conducted a retrospective review of 128 adult patients with AML who received induction therapy by way of PICC insertion between 2012 and 2019. Results The median duration of PICC insertion was 30 days. The incidence rate of catheter-related bloodstream infection (CRBSI) was 2.4% at 30 days, and women were more likely to suffer from CRBSI than men. Local reactions at the insertion site were observed in 56 patients; however, these events did not predict CRBSI. The incidence rates of catheter-related thrombosis (CRT) were 1.6% at 30 days. Obesity put patients at an increased risk for CRT. Unexpected PICC removal occurred in 59 patients, and women were at a higher risk of catheter removal than men. Conclusion Low PICC-related complication rates, possibly associated with high rates of catheter removal, were observed during intensive chemotherapy for AML. Women and obese patients require careful monitoring of their PICC. Procedures to achieve appropriate PICC removal without increasing the complication rate need to be considered. 相似文献
203.
Hideaki Miyake Junya Furukawa Iori Sakai Mototsugu Muramaki Masuo Yamashita Taka-aki Inoue Masato Fujisawa 《Urologic oncology》2013,31(7):1155-1160
ObjectivesTo compare the clinical outcomes of sigmoid and ileal neobladders (NBs) created following radical cystectomy.Materials and methodsThis study included 90 and 144 Japanese patients undergoing radical cystectomy and orthotopic NB reconstruction with a sigmoid and ileal segment, respectively. Postoperative clinical outcomes between the sigmoid and ileal NB groups (SNBG and INBG) were compared.ResultsIn this series, 110 early and 51 late complications occurred in 71 and 41 patients, respectively; however, there was no significant difference in the incidence of complications between SNBG and INBG. At 1 year postoperatively, there were no significant differences in the proportion of spontaneous voiders and the continence status between these 2 groups; however, despite the lack of significant differences in the maximal flow rate and voided volume, the post-void residual in SNBG was significantly smaller than that in INBG. Voiding functional outcomes at 5 years postoperatively were also obtained from 28 and 49 in SNBG and INBG, respectively. Although there were no significant changes in the functional outcomes in SNBG, the proportion of spontaneous voiders and post-void residual in INBG at 5 years postoperatively were significantly poorer than those at 1 year postoperatively. Furthermore, the postoperative health-related quality of life assessed by a Short-Form 36 survey did not show any significant differences in all 8 scores between these 2 groups.ConclusionsBoth types of NB reconstruction resulted in comparatively satisfactory outcomes; however, the voiding function, particularly that on long-term follow-up, in SNBG appeared to be more favorable than that in INBG. 相似文献
204.
Junya Nuta Naoki Shingaki Yoshiyuki Ida Ryo Shimizu Shinya Hayami Masaki Ueno Kazuhiro Fukatsu Masahiro Itonaga Takeichi Yoshida Yoshimasa Maeda Kosaku Moribata Hisanobu Deguchi Takao Maekita Mikitaka Iguchi Jun Kato Hiroki Yamaue Hideyuki Tamai 《Ultrasound in medicine & biology》2017,43(9):1829-1836
The present study aimed to elucidate the association between post-vascular–phase (Kupffer-phase) images from contrast-enhanced ultrasonography (CEUS) with perfluorobutane microbubbles and metastatic recurrences after the resection of hepatocellular carcinoma (HCC). The study examined 73 patients with solitary HCC ≤5 cm in diameter who underwent CEUS before resection. HCC was defined as irregular type (including an irregular defect on Kupffer-phase images) or non-irregular type. Intrahepatic metastatic recurrence was defined as >3 intrahepatic recurrences. Metastatic recurrence included both extrahepatic and intrahepatic recurrences. Frequencies of microscopic portal invasion and intrahepatic metastasis were significantly higher in the irregular group than in the non-irregular group. Cumulative 5-y metastatic recurrence rates in the irregular and non-irregular groups were 43% and 7% (p = 0.028), respectively. Multivariate analyses identified Kupffer-phase findings as a factor significantly related to metastatic recurrence. In conclusion, HCCs with an irregular defect during Kupffer-phase CEUS are characterized by more frequent microscopic vascular invasion and intrahepatic metastasis and are significantly associated with metastatic recurrence after resection. 相似文献
205.
206.
Yoshiyuki Ikeda Shin-ichi Kosugi Ken Nishikura Manabu Ohashi Tatsuo Kanda Takashi Kobayashi Katsuyoshi Hatakeyama 《Gastric cancer》2007,10(1):63-68
Gastric carcinosarcoma often presents with an elevated lesion or increased thickness of the stomach wall. Histological diagnosis
is achieved using conventional hematoxylin and eosin staining to confirm the coexistence of both epithelial and mesenchymal
elements. We report a case of gastric carcinosarcoma presenting as a large mass in the epigastric region. Specimens obtained
by endoscopic biopsy and surgical excision showed diffuse proliferation of atypical cells in sheet formation. No mucus production
or glandular structures were apparent, but immunoreactivity for both epithelial and mesenchymal markers was noted. These findings
led to a definitive diagnosis of gastric carcinosarcoma. Immunohistochemical analysis is useful for the early diagnosis and
treatment of gastric carcinosarcoma. 相似文献
207.
目的:观察冰黄肤乐软膏联合奥深软膏治疗寻常型银屑病的疗效及安全性.方法:选择84例寻常型银屑病患者,随机分入治疗组和对照组,治疗组36例用冰黄肤乐软膏联合奥深软膏,每日2次,对照组48例仅外涂冰黄肤乐软膏,每日3次或奥深软膏,每日2次,疗程均为14天.结果:用药1个疗程,三组疗效无显著性差异.用药2个疗程后治疗组显效率为83.33%,冰黄肤乐对照组有效率为50.00%,奥深软膏对照组显效率为53.85%,三组比较差异有显著性(P<0.05),均无严重不良反应发生.结论:冰黄肤乐软膏联合奥深软膏治疗寻常型银屑病疗效好,患者依从性强. 相似文献
208.
Hiroshi Soda M. Oka Masaaki Fukuda Akitoshi Kinoshita Akira Sakamoto J. Araki Satoru Fujino Naomi Itoh Koichi Watanabe Tetsuro Kanda Masamoto Nakano Kohei Hara 《Cancer chemotherapy and pharmacology》1996,38(1):9-12
A prospective randomized study was conducted to determine the optimal schedule of rhG-CSF (recombinant human granulocyte
colony-stimulating factor). A group of 33 lung cancer patients treated with MVP therapy (mitomycin, vindesine, and cisplatin)
were randomly assigned to three groups: an early prophylaxis group in which rhG-CSF was initiated on day 2 of the MVP cycle;
a late prophylaxis group in which rhG-CSF was initiated on day 8; and a therapeutic group in which rhG-CFS was initiated after
the onset of neutropenia. Ten patients who had received MVP therapy without rhG-CSF were also analyzed as a no-support group.
The incidence of neutropenia was 80% (16/20 courses) in the early prophylaxis group, 44% (8/18) in the late prophylaxis group,
94% (17/18) in the therapeutic group, and 94% (16/17) in the no-support group. The incidence of neutropenia in the late prophylaxis
group was less than in the early prophylaxis group (P<0.05), the therapeutic group (P<0.01), and the no-support group (P<0.01). The late prophylactic rhG-CSF schedule was therefore more effective in countering neutropenia than either the early
prophylactic or therapeutic schedule.
Received: 13 January 1995 / Accepted: 11 August 1995 相似文献
209.
Takatoshi Ogino M.D. Yasushi Kanda M.D. Akira Kawakita M.D. Nobuyuki Yamagrchi M.D. Masahide Futamura M.D. Haruo Goto M.D. 《Pediatrics international》1988,30(1):89-93
The ultrasonographic findings in periventricular leukomalacia (PVL) in the newborn are described, and the relationship between PVL and group B streptococcal (GBS) infection is discussed. Two newborn infants (one preterm and one term) suffered from early onset GBS sepsis with shock; they showed increased echogenicity in the periventricular regions; one of them developed cystic changes. These findings might be due to decreased perfusion of the periventricular end arterial zone. It is suggested that serial ultrasonography should be performed in neonates who suffer hypoxic-ischemic brain injury. 相似文献
210.
Katoh Takayuki Ishige Toshiyuki Kasai Hazimu Naitoh Junya Kaneko Toshio Kitamura Takeshi Nagao Koichi Matsuzaki Osamu 《European archives of oto-rhino-laryngology》1984,240(2):139-144
Summary During the last three decades, 586 cases of parotid gland tumor have been extirpated in our clinic. The tumors were malignant in 170 cases and, of these, facial nerve paralysis was observed at first examination in 59 patients. This paper deals with the retrospective study of these cases and is chiefly concerned with the histological types and facial nerve paralysis. 相似文献