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81.
Focal acute bacterial nephritis is a localized bacterial infection of the kidney presenting as an inflammatory mass not containing drainable pus. The further distinction between acute focal bacterial nephritis and other renal masses is aided by the appropriate use of renal sonography and computed tomography. We report 4 cases with this entity. 相似文献
82.
Extrinsic allergic alveolitis: inhibitory effects of pentoxifylline on cytokine production by alveolar macrophages. 总被引:1,自引:0,他引:1
Zhaohui Tong Baomin Chen Huaping Dai Peter C Bauer Josune Guzman Ulrich Costabel 《Annals of allergy, asthma & immunology》2004,92(2):234-239
BACKGROUND: Pentoxifylline is a well-established drug with hemorheologic properties. Various evidence suggests an additional therapeutic potential in regard to inflammation and immunomodulation. Extrinsic allergic alveolitis (EAA) is a granulomatous disease that is driven by T-cell and alveolar macrophage (AM)-derived cytokines. OBJECTIVE: To investigate the effects of pentoxifylline on the production of tumor necrosis factor (TNF) alpha, interleukin (IL) 1beta, IL-6, IL-8, IL-10, and the soluble TNF receptors (sTNFR1 and sTNFR2) from AMs in EAA compared with dexamethasone. METHODS: The AMs from 9 patients with EAA were cultured for 24 hours with RPMI medium alone or lipopolysaccharide (LPS) (100 ng/mL) and with pentoxifylline at concentrations of 0.01, 0.1, and 1 mmol/L or 0.1-mmol/L dexamethasone. Cytokines in the culture supernatants were analyzed by enzyme-linked immunosorbent assay. RESULTS: Pentoxifylline induced a dose-dependent suppression of spontaneous TNF-alpha and IL-10 release from AMs in EAA. The spontaneous production of other cytokines was unaffected by pentoxifylline at all tested concentrations. Dexamethasone inhibited significantly only the spontaneous release of TNF-alpha. Pentoxifylline and dexamethasone also inhibited the LPS-stimulated production of all cytokines except IL-1beta and sTNFR1. CONCLUSION: Our results may be the basis for clinical trials to evaluate the role of pentoxifylline as an immunotherapeutic agent in the treatment of EAA. 相似文献
83.
Congenital anomalies associated with trisomy 18 or trisomy 13: A registry‐based study in 16 european countries, 2000–2011
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Anna Springett Diana Wellesley Ruth Greenlees Maria Loane Marie‐Claude Addor Larraitz Arriola Jorieke Bergman Clara Cavero‐Carbonell Melinda Csaky‐Szunyogh Elizabeth S. Draper Ester Garne Miriam Gatt Martin Haeusler Babak Khoshnood Kari Klungsoyr Catherine Lynch Carlos Matias Dias Robert McDonnell Vera Nelen Mary O'Mahony Anna Pierini Annette Queisser‐Luft Judith Rankin Anke Rissmann Catherine Rounding Sylvia Stoianova David Tuckerz Natalya Zymak‐Zakutnia Joan K. Morris 《American journal of medical genetics. Part A》2015,167(12):3062-3069
84.
Bellomio V Spindler A Lucero E Berman A Santana M Moreno C Hidalgo RP Paira S Graf C Maldonado Cocco JA Citera G Arriola MS Gómez G Barreira JC Messina O Asnal C Carrillo D Gervilla A García L Máscolo M De la Sota M D Rosso G Somma LF Sosa RF Rillo O Caracciolo JA Lancioni G Gómez A 《Lupus》2000,9(5):377-381
OBJECTIVE: To analyze the factors associated with mortality, survival and causes of death in patients with systemic lupus erythematosus (SLE) in Argentina. PATIENTS AND METHOD: A series of 366 patients with SLE (45 men and 321 women), mean age 29 y (range 11-70 y) and mean disease duration 6 y, was evaluated from 1990 to 1998. A total of 57 clinical, serological and therapeutic variables were studied. RESULTS: Five- and 10-year survival was 91% and 85% respectively. Forty four patients died (12%): 54% due to sepsis and 32% due to active SLE. Mortality risk factors included heart involvement CRR 3.82), hyperlipidemia (RR 2.72), renal damage (RR 2. 62), infections (RR 2.44), lung disease (RR 2.20) and myositis (RR 2. 07). High-dose prednisone (RR 3.4) or cyclophosphamide (RR 9.19) treatments increased the risk of sepsis (P=0.003) as a cause of death. However, corticosteroids, antimalarial agents and accumulated cyclophosphamide doses proved to be protective factors in overall mortality figures (RR <1). CONCLUSIONS: The main risk factors of death in SLE were heart involvement, hyperlipidemia and renal damage. Treatment with steroids, antimalarial agents and cyclophosphamide improved survival. High-dose corticosteroids and cyclophosphamide were associated with sepsis as a cause of death. 相似文献
85.
Solá Dalenz V Pardo Schanz J Ricci Arriola P Guiloff Fische E 《Actas urologicas espa?olas》2005,29(10):977-980
ObjectiveWe presented our experience in the concomitant correction of cystocele and rectocele with polypropylene monofilament mesh (Gynemesh PS), with transvaginal free tension technique.MethodDuring 2004 correction was made in 7 patients, Urogynecologic and Vaginal Surgery Unit of Gynecology and Obstetrics Department, Las Condes Clinic. Medium age 54 years old, weight 64 kgs. In four patients we used a third mesh for correction of urinary incontinence by TVT-O.ResultsThey don’t present intraoperative complications, neither in immediate or delayed postoperative time. We not observed hematoma, infection, erosion or exposition mesh. Cure of cystocele and rectocele was in the 100% of patients. Complications have not appeared, 4 cases completed three months of observation, 2 cases two months and 1 case one month.DiscussionThe use of protesic polypropylene multifilament macropore mesh in the concomitant correction of cistocele and rectocele, by transvaginal route with tension free technique seems to be a safe and effective surgery procedure. 相似文献
86.
Bronchoalveolar lavage in drug-induced lung disease 总被引:3,自引:0,他引:3
Given the varying histologic reactions and differ-ent mechanisms of action, it is not surprising that no uniform constellation of BAL changes is seen in drug-induced lung disease. BAL findings are not specific for any drug-induced lung disease and the definitive diagnosis cannot rely solely on the BAL findings. BAL findings can, however, contribute to the expected clinicopathologic pattern of a given drug-induced lung disease. BAL also is helpful in the differential diagnosis, primarily in the exclusion of an infective cause and of involvement of the lungs by the underlying disease (eg, metastatic cancer or malignant lymphoma). 相似文献
87.
88.
Xavier Muñoz Pilar Amiano David Celorrio Miren Dorronsoro María‐José Sánchez José M. Huerta Aurelio Barricarte Larraitz Arriola Carmen Navarro Esther Molina‐Montes M. Dolores Chirlaque Eva Ardanaz Laudina Rodriguez Eric J. Duell Elizabeth Hijona Marta Herreros‐Villanueva Núria Sala Luis Bujanda 《Addiction (Abingdon, England)》2012,107(12):2117-2127
89.
Tyler M. Sharp Nicole M. Roth Jomil Torres Kyle R. Ryff Nicole M. Pérez Rodríguez Chanis Mercado Maria del Pilar Diaz Padró Maria Ramos Raina Phillips Matthew Lozier Carmen S. Arriola Michael Johansson Elizabeth Hunsperger Jorge L. Mu?oz-Jordán Harold S. Margolis Brenda Rivera García 《MMWR. Morbidity and mortality weekly report》2014,63(48):1121-1128