全文获取类型
收费全文 | 45189篇 |
免费 | 4936篇 |
国内免费 | 124篇 |
专业分类
耳鼻咽喉 | 632篇 |
儿科学 | 1262篇 |
妇产科学 | 1261篇 |
基础医学 | 7011篇 |
口腔科学 | 1051篇 |
临床医学 | 6137篇 |
内科学 | 8397篇 |
皮肤病学 | 594篇 |
神经病学 | 3630篇 |
特种医学 | 1507篇 |
外国民族医学 | 1篇 |
外科学 | 6037篇 |
综合类 | 919篇 |
一般理论 | 29篇 |
预防医学 | 4675篇 |
眼科学 | 676篇 |
药学 | 3678篇 |
中国医学 | 61篇 |
肿瘤学 | 2691篇 |
出版年
2021年 | 617篇 |
2020年 | 409篇 |
2019年 | 703篇 |
2018年 | 802篇 |
2017年 | 578篇 |
2016年 | 719篇 |
2015年 | 753篇 |
2014年 | 1034篇 |
2013年 | 1583篇 |
2012年 | 2100篇 |
2011年 | 2164篇 |
2010年 | 1217篇 |
2009年 | 1090篇 |
2008年 | 1884篇 |
2007年 | 1994篇 |
2006年 | 1918篇 |
2005年 | 1885篇 |
2004年 | 1793篇 |
2003年 | 1746篇 |
2002年 | 1775篇 |
2001年 | 1563篇 |
2000年 | 1600篇 |
1999年 | 1385篇 |
1998年 | 628篇 |
1997年 | 523篇 |
1996年 | 446篇 |
1995年 | 482篇 |
1994年 | 440篇 |
1993年 | 410篇 |
1992年 | 1120篇 |
1991年 | 1057篇 |
1990年 | 1035篇 |
1989年 | 961篇 |
1988年 | 881篇 |
1987年 | 905篇 |
1986年 | 869篇 |
1985年 | 886篇 |
1984年 | 707篇 |
1983年 | 602篇 |
1982年 | 427篇 |
1981年 | 348篇 |
1980年 | 364篇 |
1979年 | 578篇 |
1978年 | 442篇 |
1977年 | 366篇 |
1976年 | 369篇 |
1974年 | 379篇 |
1973年 | 334篇 |
1972年 | 338篇 |
1971年 | 304篇 |
排序方式: 共有10000条查询结果,搜索用时 9 毫秒
991.
992.
Wayne E. Jones Jr. Jasper Chiguma Edwin Johnson Ashok Pachamuthu Daryl Santos 《Materials》2010,3(2):1478-1496
Nanocomposites made up of polymer matrices and carbon nanotubes are a class of advanced materials with great application potential in electronics packaging. Nanocomposites with carbon nanotubes as fillers have been designed with the aim of exploiting the high thermal, electrical and mechanical properties characteristic of carbon nanotubes. Heat dissipation in electronic devices requires interface materials with high thermal conductivity. Here, current developments and challenges in the application of nanotubes as fillers in polymer matrices are explored. The blending together of nanotubes and polymers result in what are known as nanocomposites. Among the most pressing current issues related to nanocomposite fabrication are (i) dispersion of carbon nanotubes in the polymer host, (ii) carbon nanotube-polymer interaction and the nature of the interface, and (iii) alignment of carbon nanotubes in a polymer matrix. These issues are believed to be directly related to the electrical and thermal performance of nanocomposites. The recent progress in the fabrication of nanocomposites with carbon nanotubes as fillers and their potential application in electronics packaging as thermal interface materials is also reported. 相似文献
993.
994.
J. Ravindran C. Cavill C. Balakrishnan S. M. Jones E. Korendowych N. J. McHugh 《Arthritis care & research》2010,62(1):86-91
Objective
To use a modified Sharp score (MSS) to measure radiologic progression and to assess its relationship to other radiologic features, peripheral joint disease, and physical function in psoriatic arthritis (PsA).Methods
Two sets of hand radiographs (median interval 5.75 years) in 139 patients with established PsA were scored using an MSS. Seventy‐four patients had standardized clinical joint and Health Assessment Questionnaire (HAQ) scores and other radiologic features of PsA documented at baseline and followup (median interval 5 years).Results
Radiologic damage was present in 58% of patients at baseline and 74% at followup. The median MSS and its components, erosion score and joint space abnormality score, were significantly greater at followup (P < 0.001). The median MSS progression was +1.08 units/year. There was strong correlation between MSS and clinical joint scores at baseline and followup (r = 0.72 and r = 0.81, respectively). There was weak correlation between MSS and HAQ at baseline (r = 0.29), but stronger correlation at followup (r = 0.48). There was a strong association between MSS and other characteristic radiologic features of PsA (bony proliferation, periostitis, bony ankylosis) at baseline and followup (P < 0.001). However, the presence of soft‐tissue swelling on radiographs at baseline was the only radiologic parameter associated with an increased rate of change of MSS (corrected P < 0.006).Conclusion
The MSS shows good construct validity with measures of peripheral joint involvement such as clinical joint scores and other radiologic features of PsA, and is able to demonstrate that radiologic damage is progressive beyond early disease. 相似文献995.
James F. X. Jones 《The Journal of physiology》2009,587(12):2715-2715
996.
997.
998.
BACKGROUND: Measuring blood pressure with mercury-independent alternatives is rapidly gaining attention. Mercury will be phased out of clinical use as a result of environmental, health and safety concerns and it is of vital importance that any alternative to mercury has to be of a recognized standard. We assessed the accuracy of the Maxi Stabil 3 aneroid device in an adult population according to a modified British Hypertension Society protocol (with the low systolic category changed from less than 90 mmHg to less than 100 mmHg). POPULATION: Eighty-five subjects were recruited from among staff and patients at Guy's and St Thomas' Hospitals, London, UK. METHODS: The aneroid device was connected in parallel to two mercury sphygmomanometers. Nine sequential same-arm measurements were taken from each subject by two trained observers, alternating between mercury sphygmomanometry and the aneroid device. Simultaneous mercury readings were also recorded for additional analysis. RESULTS: The device achieved an A grade for both systolic and diastolic pressures and fulfilled the requirements of the Association for the Advancement of Medical Instrumentation. The mean and standard deviation for systolic and diastolic pressures respectively were -0.6 (4.6) mmHg and -1.3 (3.5) mmHg in sequential analysis, and -1.3 (2.2) mmHg and -1.9 (2.7) mmHg in simultaneous analysis. CONCLUSION: The Maxi Stabil aneroid device can be recommended for use in an adult population. 相似文献
999.
Din-Dzietham R Couper D Evans G Arnett DK Jones DW 《American journal of hypertension》2004,17(4):304-313
BACKGROUND: Impairment of arterial dilation is thought to occur earlier than arterial wall thickening in the atherosclerotic process. In comparison with whites, African Americans reportedly have a generalized attenuation of their vasodilation mechanisms. We set out to evaluate arterial stiffness and its correlates by ethnicity, hypothesizing that African Americans would have stiffer common carotid arteries (ie, lower arterial distension for a given systolic pressure) than their white counterparts. METHODS: The study population included 268 African Americans and 2459 whites, who were aged 45 to 64 years at baseline examination in 1986 to 1989, free of coronary heart disease and stroke/transient ischemic attack, from Forsyth County, North Carolina. The beta stiffness index and pulsatile arterial diameter change were derived from brachial blood pressure and from echo-tracked systolic and diastolic carotid arterial diameters. RESULTS: African Americans had stiffer carotid arteries than their white counterparts, with a right shift of the beta stiffness index distribution. After adjustment for selected cardiovascular risk factors, the mean beta stiffness index was 9% higher for African Americans (mean +/- SEM: 11.3 +/- 0.3) than for whites (mean +/- SEM: 10.3 +/- 0.1) among participants not taking antihypertensive medication. Socioeconomic status and comorbidities were differentially associated with arterial stiffness by ethnicity. Specifically, the association between these correlates and beta stiffness index was stronger in African Americans than in whites. CONCLUSIONS: This report on arterial mechanics in African Americans suggests that large artery stiffening either occurs earlier, or is more accelerated in African Americans than in whites in our sample, perhaps as a result of earlier exposure to multiple risk factors. This finding may have implications for hypertension prevention, as arterial stiffness is associated with the development of hypertension. 相似文献
1000.
Francis C White Percy J Russell Muhammad Ashraf Paul Wolf Lyall Higginson David Jones Colin M Bloor 《American heart journal》1981,102(4):686-697
Coronary artery narrowing (CAN), which reduced resting coronary blood flow (BF) by 50%, was induced in 10 conscious dogs and was maintained for 4 hours. Five additional dogs (group 1) with complete coronary artery occlusion were compared to the dogs with CAN. serum isoenzymes of creatine phosphokinase (CK) and latate dehydrogenase (LD) were monitored hourly in all groups. After 36 hours, samples were obtained for regional myocardial BF, quantitative histology, and quantitative ultrastructural (EM) morphology. Six dogs with CAN had small infarcts (MI) of less than 1 gm and persistent myocardial cell injury (group 2). The other four dogs with CAN had only persistent myocardial cell injury by ultrastructural criteria (group 3). Peak serum CK activities in groups 2 and 3 were similar, as were MI sizes calculated from serum CK and myocardial depletion. MB CK was of diagnostic value in group 1 but not in groups 2 and 3. The ratio of had diagnostic value in all three groups. MI size by enzyme estimates was consistently higher than planimetered MI size at autopsy in both groups 1 and 2. All three groups had significant amounts of ultrastructural damage outside of histologically demonstrated MI. These findings suggest that (1) gross and histologic MI size determination of 36 hours after ischemia underestimate extent of damage, and (2) ultrastructural cell changes cause significant release of CK and LD in coronary disease (CAD). 相似文献