全文获取类型
收费全文 | 80061篇 |
免费 | 3827篇 |
国内免费 | 326篇 |
专业分类
耳鼻咽喉 | 1036篇 |
儿科学 | 2146篇 |
妇产科学 | 1985篇 |
基础医学 | 10590篇 |
口腔科学 | 2957篇 |
临床医学 | 5811篇 |
内科学 | 19708篇 |
皮肤病学 | 1653篇 |
神经病学 | 6841篇 |
特种医学 | 2439篇 |
外国民族医学 | 6篇 |
外科学 | 9484篇 |
综合类 | 425篇 |
一般理论 | 28篇 |
预防医学 | 8412篇 |
眼科学 | 1306篇 |
药学 | 5347篇 |
中国医学 | 303篇 |
肿瘤学 | 3737篇 |
出版年
2023年 | 541篇 |
2022年 | 1006篇 |
2021年 | 2189篇 |
2020年 | 1171篇 |
2019年 | 1875篇 |
2018年 | 3917篇 |
2017年 | 2400篇 |
2016年 | 1791篇 |
2015年 | 1897篇 |
2014年 | 2616篇 |
2013年 | 3470篇 |
2012年 | 5325篇 |
2011年 | 5670篇 |
2010年 | 3053篇 |
2009年 | 2547篇 |
2008年 | 4568篇 |
2007年 | 4706篇 |
2006年 | 4356篇 |
2005年 | 4361篇 |
2004年 | 3963篇 |
2003年 | 3708篇 |
2002年 | 3467篇 |
2001年 | 1845篇 |
2000年 | 1958篇 |
1999年 | 1597篇 |
1998年 | 586篇 |
1997年 | 386篇 |
1996年 | 376篇 |
1995年 | 328篇 |
1994年 | 270篇 |
1993年 | 277篇 |
1992年 | 811篇 |
1991年 | 641篇 |
1990年 | 615篇 |
1989年 | 529篇 |
1988年 | 471篇 |
1987年 | 495篇 |
1986年 | 426篇 |
1985年 | 374篇 |
1984年 | 277篇 |
1983年 | 239篇 |
1979年 | 199篇 |
1978年 | 173篇 |
1977年 | 150篇 |
1975年 | 176篇 |
1974年 | 181篇 |
1973年 | 170篇 |
1972年 | 168篇 |
1971年 | 163篇 |
1968年 | 150篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
31.
Spread of an Enterococcus faecalis sequence type 6 (CC2) clone in patients undergoing selective decontamination of the digestive tract 下载免费PDF全文
Izaskun Muruzábal‐Lecumberri Cecilia Girbau Andrés Canut Rodrigo Alonso Aurora Fernández‐Astorga 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2015,123(3):245-251
Enterococcus faecalis (E. faecalis) is a common cause of nosocomial infection in immunocompromised patients. The presence and dissemination of high‐risk clonal complexes, such as CC2, is an ongoing problem in hospitals. The aim of this work was to characterize 24 E. faecalis isolates from ICU patients undergoing selective decontamination of the digestive tract (SDD) by phenotypical (antimicrobial susceptibility) and genotypical (presence of virulence genes, RAPD‐PCR and MLST) methods. Our results showed high prevalence of the ST6 E. faecalis clone (91.6%), especially adapted to the hospital environment, with a multidrug resistance pattern and a multitude of putative virulence genes. In addition, ST179 (4.2%) and ST191 (4.2%) were detected. By RAPD–PCR analysis, the 22 isolates identified as ST6 showed six different DNA patterns, while the two remaining isolates, ST179 and ST191, showed two additional profiles. CC2 is a known clonal complex with high adaptability to hospital environment and worldwide distribution. The high prevalence of the ST6 clone in the studied population could be related to the presence of gentamicin in the SDD mixture since most strains were gentamicin resistant. Consequently, strict surveillance should be applied for rapid detection and control of this clone to prevent future spread outside the ICU. 相似文献
32.
Thaís dos Santos Fontes Pereira Carolina Cavalieri Gomes Peter A Brennan Felipe Paiva Fonseca Ricardo Santiago Gomez 《Journal of oral pathology & medicine》2019,48(1):3-9
Fibrous dysplasia is a non‐neoplastic developmental process that affects the craniofacial bones, characterized by painless enlargement as a result of bone substitution by abnormal fibrous tissue. Postzygotic somatic activating mutations in the GNAS1 gene cause fibrous dysplasia and have been extensively investigated, as well as being helpful in the differential diagnosis of the disease. Fibrous dysplasia may involve one (monostotic) or multiple bones (polyostotic), sporadically or in association with McCune‐Albright syndrome, Jeffe‐Lichenstein syndrome, or Mazabreud syndrome. This review summarizes the current knowledge on fibrous dysplasia, emphasizing the value of integrating the understanding of its molecular pathogenesis with the clinical, radiological, and histopathological features. In addition, we address important aspects related to the differential diagnosis and patient management. 相似文献
33.
34.
35.
A. Prado Rodríguez R. Mato Búa L. Mera Mujico J. Arca Suárez M. López Sánchez L. Sampayo Rodríguez P. Rama-Maceiras 《Revista espa?ola de anestesiología y reanimación》2021,68(6):361-366
Serum lactate is a non-specific marker of tissue hypoperfusion. Elevated serum lactate is used in the differential diagnosis of acute intestinal ischemia. Although this practice is controversial, in the absence of other validated markers lactate is still used because of its high sensitivity.We present the cases of two patients who developed acute mesenteric ischemia as a post-surgical complication. The patients reported moderate abdominal pain —a non-specific symptom in the postoperative context— and tests showed progressively increasing serum lactate levels, which facilitated suspicion and subsequent diagnostic confirmation through an imaging test.These cases highlight the physiopathological importance of lactate elevation in the perioperative context and of performing a differential diagnosis of its possible causes, including mesenteric ischemia. Although the outcome was negative in the first case, early suspicion allowed us to make an effective diagnosis and administer appropriate treatment in the second patient. 相似文献
36.
37.
38.
39.
40.