全文获取类型
收费全文 | 826936篇 |
免费 | 38358篇 |
国内免费 | 1096篇 |
专业分类
耳鼻咽喉 | 9383篇 |
儿科学 | 26606篇 |
妇产科学 | 17763篇 |
基础医学 | 124885篇 |
口腔科学 | 16647篇 |
临床医学 | 73033篇 |
内科学 | 151185篇 |
皮肤病学 | 14190篇 |
神经病学 | 61324篇 |
特种医学 | 33447篇 |
外国民族医学 | 53篇 |
外科学 | 126660篇 |
综合类 | 11749篇 |
现状与发展 | 3篇 |
一般理论 | 279篇 |
预防医学 | 67799篇 |
眼科学 | 17297篇 |
药学 | 59647篇 |
3篇 | |
中国医学 | 1913篇 |
肿瘤学 | 52524篇 |
出版年
2021年 | 6349篇 |
2019年 | 6189篇 |
2018年 | 29577篇 |
2017年 | 22781篇 |
2016年 | 25712篇 |
2015年 | 8795篇 |
2014年 | 11696篇 |
2013年 | 17015篇 |
2012年 | 30617篇 |
2011年 | 46535篇 |
2010年 | 32916篇 |
2009年 | 24500篇 |
2008年 | 42409篇 |
2007年 | 46786篇 |
2006年 | 25588篇 |
2005年 | 26645篇 |
2004年 | 27130篇 |
2003年 | 26906篇 |
2002年 | 24512篇 |
2001年 | 23923篇 |
2000年 | 24358篇 |
1999年 | 20410篇 |
1998年 | 6987篇 |
1997年 | 5825篇 |
1996年 | 5679篇 |
1995年 | 5402篇 |
1992年 | 15269篇 |
1991年 | 16746篇 |
1990年 | 16802篇 |
1989年 | 16427篇 |
1988年 | 15102篇 |
1987年 | 14973篇 |
1986年 | 13951篇 |
1985年 | 13543篇 |
1984年 | 10305篇 |
1983年 | 8867篇 |
1982年 | 5295篇 |
1981年 | 4951篇 |
1979年 | 9558篇 |
1978年 | 7056篇 |
1977年 | 5744篇 |
1976年 | 6038篇 |
1975年 | 7095篇 |
1974年 | 7912篇 |
1973年 | 7599篇 |
1972年 | 6896篇 |
1971年 | 6618篇 |
1970年 | 6167篇 |
1969年 | 5689篇 |
1968年 | 5356篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
991.
992.
Summary The psychophysiological action of beta-erythroidin hydrochloride has been presented together with a brief survey of the development of the drug and its therapeutic utilization in the modification of the metrazol convulsion. The problem of idiosyncrasy to this drug has been discussed and the use of prostigmin as an antidote described. The writers wish to stress the fact that the use of this drug, with the above facts well in mind, can be considered a safe procedure.Supplies of the drug were prepared and obtained through the cooperation of Merck and Company, Rahway, N. J. 相似文献
993.
Fady K. Balaa T. Clark Gamblin Allan Tsung J. Wallis Marsh David A. Geller 《Journal of gastrointestinal surgery》2008,12(2):338-343
Background Application of linear stapling devices for extrahepatic vascular control in liver surgery has been well-established. However,
the technique for use of stapling devices in hepatic parenchymal transection is not well defined.
Purpose To describe the safety and efficacy of our technique for use of vascular stapling devices in hepatic parenchymal transection
during open right hepatic lobectomy is the purpose of this study.
Methodology We reviewed our experience with 101 consecutive open right hepatic lobectomies performed by a single surgeon between January
2003 and July 2006, in which vascular staplers were utilized for the parenchymal transection phase.
Results Of the 101 patients who underwent resection, 53 (52%) were female. The mean age was 58 years. Malignant disease was the indication
for resection in the majority of patients (88%). Of those with cancer, 78% (69 of 89) had metastatic colorectal cancer, 6%
(5 of 89) had metastatic neuroendocrine tumor, 4% (4 of 89) had hepatocellular carcinoma, 4% (4 of 89) had cholangiocarcinoma,
and the remaining 8% were other metastatic cancers. Twelve patients (12%) underwent resection for hepatic adenoma or symptomatic
benign disease (FNH or hemangioma). Forty-eight patients (48%) underwent a major ancillary procedure at the time of hepatic
resection. Thirty-nine patients (39%) had a nonanatomic wedge resection of a left lobe lesion, 27 patients (27%) had one or
more lesions treated with radiofrequency ablation (RFA), and 6 patients (6%) were treated with a synchronous bowel resection.
The median total operative time was 336 min (range 155–620 min). A Pringle maneuver for temporary vascular inflow occlusion
was utilized in all cases, with a median time of 9 min (range 4–17 min). Ten patients (10%) required blood transfusion during
surgery or in the postoperative period. The maximum transfusion was 2 U of packed red blood cells (PRBC) in seven patients
and 1 U of PRBC in three patients. The mean nadir postoperative hematocrit was 28.2. All patients with malignant disease had
tumor-free margins at the completion of the procedure. The average hospital length of stay was 6.0 days. One patient (1%)
developed a clinically significant bile leak requiring a postoperative endoscopic retrograde cholangiography (ERCP). No patient
required reoperation. The 30 and 60-day postoperative survival was 100%.
Conclusion These findings indicate that application of vascular stapling devices for parenchymal transection in major hepatic resection
is a safe technique, with low transfusion requirements and minimal postoperative bile leak. The technique allows for rapid
transection of the entire right hepatic lobe in under 10 min. Short video clips of the technique will be demonstrated.
Presented at the 2007 American Hepato–Pancreato–Biliary Association, Las Vegas, Nevada, April 19–22, 2007 (oral presentation/video
presentation). 相似文献
994.
Kyu-Won Shim Tae-Gon Kim Chang-Ok Suh Jae-Ho Cho Chul-Joo Yoo Joong-Uhn Choi Jung-Hee Kim Dong-Seok Kim 《Child's nervous system》2007,23(10):1155-1161
Object A radiation dose of 40–50 Gy is able to produce a cure rate of more than 90% in intracranial pure germinoma. However, many
attempts have been made to reduce the dose and volume of radiation without compromising the disease control rate because of
the toxicity of irradiation. This retrospective study is intended to provide the physician with an appropriate therapeutic
strategy.
Materials and methods We reviewed a series of 10 recurrent germinomas among 117 germinomas diagnosed histologically or clinically between 1979 and
2002. These patients involved underwent three different treatment modalities; radiation alone (N = 71), chemotherapy alone (N = 9), and combined therapy (N = 37). The 10-year overall and relapse-free survival rates were 97 and 93% in the radiation alone group, 89 and 67% in the
chemotherapy alone group, and 92 and 92% in the combined therapy group, respectively. As expected, both radiation therapy
and combined therapy were effective in controlling the disease. Tumor recurrence was closely related to the volume of radiation
but not to the dose of radiation. If the tumor bed and craniospinal axis were fully covered, the radiation dose might be reduced.
Chemotherapy alone showed earlier recurrence and a higher tumor recurrence rate. In the case of combined therapy, chemotherapy
was useful in reducing the radiation dose but revealed some toxicity (death of two patients).
Conclusions The investigation of a possible further dose reduction seems worthwhile. Radiation therapy alone with a dose of less than
40 Gy should be compared with ongoing chemotherapeutic protocols combined with low-dose irradiation. 相似文献
995.
V Caverni M Rastrelli R Aufieri R Agostino 《The journal of maternal-fetal & neonatal medicine》2004,15(2):126-128
OBJECTIVE: To assess whether dedicated ambulances would improve the efficiency of the neonatal emergency transport service (NETS). METHODS: The efficiency of NETS was investigated in the Lazio region, Italy, by comparing data collected during the first 6 months of 1997 (from 1 January to 30 June), with those collected during the same months of 2000, using NETS availability and time investment as indicators. The data yielded by the study were reported as number and percentage, and were analyzed by SPSS 10.1 software; chi2 analysis with Pearson's correction was used to assess the statistical significance of the differences between the two groups; p < 0.05 was considered statistically significant. RESULTS: Our investigation showed a reduced availability of the service in 2000, compared to 1997 (90.4% vs. 95%; p < 0.03). We also noted that in 2000 all dedicated ambulances remained off duty for 26 days, owing to engine failure. The response time and the total transfer time where much longer in 2000 than in 1997 (response time > 30 min in 8% vs. 3%, p < 0.008; total transfer time > 120 min in 37% vs. 30%, p < 0.04). CONCLUSIONS: The reduced efficiency in 2000 was mainly due to the lack of ambulances used to replace the dedicated ambulances. However, the type of ambulance that may provide the best replacement for NETS remains an unsolved question. 相似文献
996.
Alfred Philip James Lake BSc MBBS FFARCS ; Kathiravelpillai Puvanachandra MBBS DO FRCS FRCOphth 《Pain practice》2004,4(2):130-131
Abstract: Stellate ganglion block is commonly used to treat the sympathetically maintained pain which may occur in one‐third of patients with complex regional pain syndrome type 1. A complication that followed a single block and presented a diagnostic dilemma for the ophthalmologist is reported. 相似文献
997.
Yi-Hwa Liu 《Journal of nuclear cardiology》2007,14(4):483-491
Conclusion Quantification of nuclear cardiac images provides a secondary support in reading myocardial perfusion images and improves
the reproducibility in the diagnosis of cardiovascular diseases. The technology for the remote Web reading of nuclear cardiac
images and the quantitative data allows for an easy and secured access to patient studies without the limitations of time
and space. The recent increasing interests and applications in molecular targeted imaging have opened a new field in nuclear
cardiology, and absolute image quantification of the focal tracer uptake in the myocardium is exceedingly critical for the
quantitative analysis of molecular targeted images. 相似文献
998.
999.
CASE REPORT: A 12-year-old boy who had a history of Kawasaki disease 9 years ago experienced a subarachnoid hemorrhage by ruptured right posterior cerebral artery aneurysm. On day 1 operation, as the aneurysm was very fragile and bled easily, two intraoperative ruptures, including a very premature rupture, were encountered. As a result, a left hemiparesis especially severe in the left hand was caused by the right anterior thalamic infarction due to the occlusion of a thalamo-perforating artery arising near the neck of the aneurysm. DISCUSSION: The histopathological examination of the intraoperative excised aneurysmal dome disclosed the thickening of the endothelial inner due to the endothelial hypertrophy and the invasion of inflammatory cells. This finding of the aneurysm was partially mimicking the finding of the coronary artery of the patients with Kawasaki disease. The combination of cerebral aneurysm and Kawasaki disease has never been reported until now, and the etiology of the aneurysm of this patient is unclear. 相似文献
1000.
B. S. Sharma Sumit Sinha V. S. Mehta A. Suri Aditya Gupta A. K. Mahapatra 《Child's nervous system》2007,23(3):327-333
Object Intracranial aneurysms are rare in children and have different epidemiological, clinical, and morphological characteristics
and outcome from those in adults.
Materials and methods We analyzed demographic, clinical, radiologic features, treatment, and outcome in 55 patients <18 years of age, treated from
Jan 1995 through December 2005.
Results Intracranial aneurysms in children below 18 years constituted 4% of all intracranial aneurysms. Internal Carotid artery (ICA)
bifurcation was the commonest location. About half of the aneurysms were complex. Three-fourth of the patients required surgical
treatment. Two patients died, constituting 5% mortality. Two patients (5%) had poor outcome, whereas the majority (90%) had
a favorable outcome.
Conclusions Pediatric aneurysms have male predominance, higher incidence of clinical features of mass effect or seizures, high incidence
of large, traumatic/mycotic aneurysms, associated illnesses and ICH/IVH and hydrocephalus, better Hunt and Hess grades at
presentation, ICA bifurcation as the commonest site, and better outcome than their adult counterparts. 相似文献