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排序方式: 共有4301条查询结果,搜索用时 15 毫秒
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Yong Tao Byunghak Kang Daniel A. Petkovich Yuba R. Bhandari Julie In Genevieve Stein-OBrien Xiangqian Kong Wenbing Xie Nicholas Zachos Shinji Maegawa Himani Vaidya Stephen Brown Ray-Whay Chiu Yen Xiaojian Shao Jai Thakor Zhihao Lu Yi Cai Yuezheng Zhang Hariharan Easwaran 《Cancer cell》2019,35(2):315-328.e6
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Multiple sclerosis is commonly associated with bladder dysfunction, which is frequently reported to be the worst aspect of
the disease. Patients may experience bothersome bladder symptoms early in the course, and this should be explored. If necessary,
a formal evaluation of the lower urinary tract should be offered. The type of bladder dysfunction may also change with time,
which highlights the need for continual follow-up assessments. Anticipated problems are incomplete bladder emptying and disorders
with urine storage, which may occur simultaneously. This may lead to symptoms of overactive bladder and recurrent urinary
tract infections. Conservative measures for management should be used initially while other sinister pathology is excluded.
Newer treatments such as botulinum toxin A and neural stimulation techniques are replacing more invasive surgical procedures.
Treatment approaches have been described and should be offered by teams who are familiar with patients having uro-neurological
complaints. 相似文献
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Sudha Vidyasagar Nataraj Muralidhar Varma C. K. Prashanth Yeshwanth Rao B. Kavitha 《International journal of diabetes in developing countries.》2011,31(3):161-165
Data from UKPDS study suggests that the onset of ß cell dysfunction in diabetes occurs well before the development of hyperglycemia. To study the concept of secondary OHA failure in type 2 diabetes patients of more than 10 years duration in a tertiary care hospital. A retrospective analysis of all the cases of type 2 diabetes mellitus of more than 10 years duration from 2002 to 2003 was done and the data was divided into three groups: oral hypoglycemic agents (OHA) only, Insulin only, OHA + insulin. ANOVA/Students t test was the primary statistical test used. Odds ratio and 95% CI were calculated to compare risks of other diseases and drug use. 62.35% were on only OHAs, 8.82% on only insulin and 28.82% on both insulin and OHAs. This confirms good efficacy of OHAs. Diabetic population in our study tends to have a preserved beta cell function and secondary OHA failure is a late feature. 相似文献
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