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11.
SUMMARY A young patient presenting with splenomegaly and hypersplenism was inadvertently found to have selective IgA deficiency. There were no symptoms of immunodeficiency and the patient responded well to splenectomy, with return of blood counts to normal without adverse effects. No other cause for the hypersplenism was found. We postulate selective IgA deficiency as a cause of splenomegaly and hypersplenism. 相似文献
12.
Horst J. Jaeger Klaus D. Mathias Udo Kempkes 《Cardiovascular and interventional radiology》1994,17(6):328-332
A 66-year-old man presented with bilateral subclavian steal syndrome (SSS) due to proximal subclavian artery occlusions. He was treated by percutaneous transluminal balloon angioplasty (PTA) and stent implantation in the left subclavian artery and by PTA alone in the right subclavian artery. We could demonstrate that interventional treatment of symptomatic bilateral SSS is possible. If PTA alone is insufficient, stent implantation should be considered. 相似文献
13.
14.
CA Schroeter† L Kaas† JJ Waterval† PM Bos‡ HAM Neumann§ 《Journal of the European Academy of Dermatology and Venereology》2007,21(9):1170-1174
AIM: The aim of this pilot study was an investigation on photodynamic therapy (PDT) whether it is a good alternative for treating periungual and subungual warts of the hands. STUDY DESIGN: Twenty patients (mean age: 30.5 years) with a total of 40 periungual and subungual warts were treated with PDT. A photosensitizer, 20%delta-aminolevulinic acid was applied on the warts. After a mean incubation time of 4.6 h (SD: 1.2), the warts were irradiated with the VersaLight for 5-30 min (15.2 +/- 4.3 min). RESULTS: After a mean of 4.5 treatments a mean clearance of 100% was achieved in 90% of the patients. One patient (5%) showed a clearance of 50% and another showed no improvement. The subungual or periungual location of the wart had no influence on the number of treatments or end result (P > 0.05). There were two recurrences during the mean follow-up period of 5.9 months (SD: 7.6). Besides mainly pain and hyperpigmentation, most treatments had no side-effects. CONCLUSION: PDT can offer a good alternative for treating periungual warts of the hands. Larger studies are indicated. 相似文献
15.
Claus Neurohr Patrick Huppmann Hanno Leuchte Martin Schwaiblmair Iris Bittmann Gundula Jaeger Rudolf Hatz Lorenz Frey Peter Überfuhr Bruno Reichart Jürgen Behr for the Munich Lung Transplant Group 《American journal of transplantation》2005,5(12):2982-2991
Bronchiolitis obliterans syndrome (BOS) is the limiting factor to long-term survival after lung transplantation. Previous studies suggested respiratory viral tract infections are associated with the development of BOS. To identify the impact of virus detection in bronchoalveolar lavage (BAL) fluid, we analyzed BAL samples from 87 consecutive lung transplant recipients for human herpesvirus (HHV)-6, Epstein-Barr virus, Herpes simplex virus 1/2, Cytomegalovirus, respiratory syncytical virus and adenovirus by PCR. Acute rejection, BOS and death were recorded for a mean follow-up time of 3.27 +/- 0.47 years. Results of PCR analysis and other potential risk factors were entered into a Cox regression analysis of BOS predictors and death. Only acute rejection was a distinct risk factor for BOS of all stages, death and death from BOS. HHV-6 was detected in 20 patients. Univariate and multivariate analysis revealed that HHV-6 was associated with an increased risk to develop BOS > orb = stage 1 and death, separate from the risk attributable to acute rejection. Identification of HHV-6 DNA in BAL fluid is a potential risk factor for BOS. Our results warrant further studies to elucidate a possible causal link between HHV-6 and BOS. 相似文献
16.
Hess B; Hasler-Strub U; Ackermann D; Jaeger P 《Nephrology, dialysis, transplantation》1997,12(7):1362-1368
BACKGROUND: Metabolic evaluation in recurrent idiopathic calcium renal
stone-formers (RCSF) was analysed with respect to the following questions:
(1) do three 24-h urines provide more diagnostic accuracy in the metabolic
evaluation of RCSF than 1 or 2 urines?; (2) does time after stone event
influence the diagnostic yield?; (3) is urine composition at weekends
different from that at mid-week?; (4) what are the prevalences of the most
important risk factors (RF) of idiopathic calcium nephrolithiasis, i.e. low
volume (LV), hypercalciuria (HC), hyperoxaluria (HO), hyperuricosuria (HU),
hypocitraturia (Hypo-Cit), and hypomagnesiuria (Hypo-Mg)?; and (5) do male
RCSF differ from females with respect to urinary RFs? METHODS: Seventy-five
RCSF (59 men, 16 women) collected three 24-h urines (U1-3) while on
free-choice diet. To account for possible variations in lifestyle and diet,
U1 and U3 had to be collected midweek and U2 at a weekend. RESULTS: When
considering all three urines together (U1 + U2 + U3), the number of RF
abnormalities/patient was 2.8 +/- 0.1, higher than numbers of any
combination of two urines or of any single urine (P = 0.0001 for all
comparisons). The number of RF abnormalities also rose with time after
stone event, from 0.8 +/- 0.1 (range 0-4) in U1 to 1.1 +/- 0.1 (range 0- 4)
in U3 (P = 0.011 vs U1). Whereas all other RF did not change between
collections, urine volume was lower in U2 (1793 +/- 90 ml) than in U1 (2071
+/- 97 ml, P = 0.0001 vs U2) and U3 (1946 +/- 97 ml, P = 0.046 vs U2). At
least 1 abnormality was found in 85.3% of all RCSF, and multiple
abnormalities occurred in 47%. The most frequent RF was HC (39%), followed
by HO and LV (32% each), Hypo-Cit (29%), HU (23%) and Hypo-Mg (19%). Males
more often had Hypo-Cit (P < 0.001) and Hypo-Mg (P < 0.01) than
females, whereas HO was more frequent in female RCSF (P < 0.025 vs
males). CONCLUSIONS: Diagnostic accuracy of metabolic evaluation in RCSF
increases both with the number of urines collected and the time passing
after a stone event. Urines collected at weekends differ from those of the
week only by their lower volumes. Abnormalities of RF for calcium
nephrolithiasis can be detected in 85.3% of RCSF, and HC is the most common
RF both in male and female RCSF.
相似文献
17.
JJ Piccininni 《The Journal of the Canadian Chiropractic Association》1994,38(4):223-226
This paper examines various devices used in strength building exercise programs. These include free weights, pulley machines, variable resistance weight machines, isokinetic units and elastic tubing and banding. Advantages and disadvantages of each are discussed and examined from the view point of the health care provider and the suitability of each type of device for prescribed progressive resistance exercise programs for patients. In addition to such practical aspects such as cost and maintenance, biomechanical factors, types of contraction elicited, ease of patient instruction and proprioception benefits are also compared in order to assist the clinician in selecting the most appropriate equipment for each individual patient. 相似文献
18.
H Saxenhofer J Scheidegger C Descoeudres P Jaeger F F Horber 《Clinical nephrology》1992,38(4):219-223
Loss of muscle mass and altered body fat distribution (i.e. increased central fat stores in the presence of normal peripheral fat stores) have been reported in patients on hemodialysis (HD), when compared to normal volunteers. Whether treatment of end-stage renal disease (ESRD) with continuous ambulatory peritoneal dialysis (CAPD) would alter body composition in a different manner than HD is unknown. To answer this question, two groups (n = 11 each) of male patients with ESRD (matched for age, residual renal function, body weight and body height as well as physical activity) were studied. Muscle mass and body fat distribution were assessed using computed tomography. Mid-thigh muscle area, peripheral and central fat stores were similar between the two groups of dialysis patients. In both patient groups muscle mass and fat stores were independent of duration of dialysis, age, daily protein intake and residual renal function. In CAPD-patients mid-thigh muscle area was correlated with plasma albumin (r = 0.56, p < 0.05), while serum cholesterol level was correlated with mediastinal fat area (r = 0.81, p < 0.01). The present results indicate that both treatment modalities of ESRD (HD vs CAPD) result in similar changes of body composition. Despite continuous glucose loading in CAPD-patients, neither central nor peripheral fat stores are increased in these subjects compared with HD treated patients. 相似文献
19.
20.
Intraluminal cyclosporine A reduces capsular thickness around silicone implants in rats 总被引:4,自引:0,他引:4
One theory of the cause of connective tissue capsule formation around silicone mammary prostheses is based on an immunological interaction. In an in vitro pilot study, it is shown that intraluminal cyclosporine A, a potent T-lymphocyte-specific immunosuppressive agent, can diffuse slowly through the outer shell of a standard double-lumen silicone breast implant. Round silicone tissue expanders containing 50 mg of cyclosporine A were implanted subcutaneously in 10 rats. Ten animals served as controls. Evaluation was performed after three months. A significant decrease in collagen capsular thickness of 21.6 +/- 5.4 microns (mean +/- standard deviation was measured histomorphometrically in the treated group compared with 39.6 +/- 8.6 microns in the control group (p less than 0.001). 相似文献